Search Results - "COULON, Christine"

Improved Automated Radiosynthesis of [18F]Dolutegravir: Toward Clinical Applications by Huvelle, Steve, Pinon, Antoine, Coulon, Christine, Bonasera, Thomas, Chapon, Catherine, Naninck, Thibaut, Le Grand, Roger, Parry, Chris M., Kuhnast, Bertrand, Caillé, Fabien

“…Positron emission tomography imaging using radiolabeled dolutegravir (DTG) is an interesting approach to understand the biodistribution of this antiretroviral…”
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Quantification of cerebral nicotinic acetylcholine receptors by PET using 2-[ F]fluoro-A-85380 and the multiinjection approach by Gallezot, Jean-Dominique, Bottlaender, Michel A, Delforge, Jacques, Valette, Héric, Saba, Wadad, Dollé, Frédéric, Coulon, Christine M, Ottaviani, Michèle P, Hinnen, Françoise, Syrota, André, Grégoire, Marie-Claude

“…The multiinjection approach was used to study in vivo interactions between α4β2* nicotinic acetylcholine receptors and 2-[18F]fluoro-A-85380 in baboons. The…”
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Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography Ligand for Nicotinic Receptors by Dollé, Frédéric, Dolci, Lilian, Valette, Héric, Hinnen, Françoise, Vaufrey, Françoise, Guenther, Ilonka, Fuseau, Chantal, Coulon, Christine, Bottlaender, Michel, Crouzel, Christian

“…The lead compound of a new series of 3-pyridyl ethers, the azetidine derivative A-85380 (3-[(S)-2-azetidinylmethoxy]pyridine), is a potent and selective ligand…”
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Synthesis, radiosynthesis and in vivo evaluation of 5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1,3-dihydrobenzoimidazol-2-[11C]one, as a potent NR1A/2B subtype selective NMDA PET radiotracer by ROGER, Gaëlle, LAGNEL, Béatrice, BESRET, Laurent, BRAMOULLE, Yann, COULON, Christine, OTTAVIANI, Michelle, KASSIOU, Michael, BOTTLAENDER, Michel, VALETTE, Heric, DOLLE, Frédéric

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Synthesis and in vivo imaging properties of [ 11C]befloxatone: A novel highly potent positron emission tomography ligand for mono-amine oxidase-A by Dolle, Frédéric, Valette, Héric, Bramoulle, Yann, Guenther, Ilonka, Fuseau, Chantal, Coulon, Christine, Lartizien, Carole, Jegham, Samir, George, Pascal, Curet, Olivier, Pinquier, Jean-Louis, Bottlaender, Michel

“…Befloxatone ( 1, (5 R)-5-(methoxymethyl)-3-[4-[(3 R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl]-2-oxazolidinone) is an oxazolidinone derivative belonging to a new…”
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Acute inhibition of cardiac monoamine oxidase A after tobacco smoke inhalation: validation study of [11C]befloxatone in rats followed by a positron emission tomography application in baboons by Valette, Héric, Bottlaender, Michel, Dollé, Frédéric, Coulon, Christine, Ottaviani, Michèle, Syrota, André

“…The in vivo characteristics of [11C]befloxatone were assessed in myocardium of rats and monkeys. A complete multicompartmental model was developed to quantify…”
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Synthesis of high-specific-radioactivity 4- and 6-[ 18F]fluorometaraminol- PET tracers for the adrenergic nervous system of the heart by Langer, Oliver, Dollé, Frédéric, Valette, Héric, Halldin, Christer, Vaufrey, Françoise, Fuseau, Chantal, Coulon, Christine, Ottaviani, Michéle, Någren, Kjell, Bottlaender, Michel, Maziére, Bernard, Crouzel, Christian

“…Fluorine-18- ( t 1/2 109.8 min) and carbon-11 ( t 1/2 20.4 min)-labeled norepinephrine analogues have been found previously to be useful…”
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Radiosynthesis and in vivo evaluation of [11C]Ro-647312: a novel NR1/2B subtype selective NMDA receptor radioligand by Dollé, Frédéric, Valette, Héric, Demphel, Stéphane, Coulon, Christine, Ottaviani, Michelle, Bottlaender, Michel, Kassiou, Michael

“…[2‐(3,4‐Dihydro‐1H‐isoquinolin‐2‐yl)‐pyridin‐4‐yl]‐dimethylamine, Ro‐647312 (1) represents a new novel class of NR1/2B subtype selective NMDA ligand. Ro‐647312…”
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Automated two-step manufacturing of [11C]glyburide radiopharmaceutical for PET imaging in humans by Caillé, Fabien, Gervais, Philippe, Auvity, Sylvain, Coulon, Christine, Marie, Solène, Tournier, Nicolas, Kuhnast, Bertrand

“…Introduction: Glyburide is an approved anti-diabetes drug binding to the sulfonylurea receptors-1 (SUR-1) and substrate of solute carrier (SLC) transporters,…”
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Automated two-step manufacturing of [11C]glyburide radiopharmaceutical for PET imaging in humans by Caillé, Fabien, Gervais, Philippe, Auvity, Sylvain, Coulon, Christine, Marie, Solène, Tournier, Nicolas, Kuhnast, Bertrand

“…Glyburide is an approved anti-diabetes drug binding to the sulfonylurea receptors-1 (SUR-1) and substrate of solute carrier (SLC) transporters, which can be…”
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Nalmefene alleviates the neuroimmune response to repeated binge‐like ethanol exposure: A TSPO PET imaging study in adolescent rats by Tournier, Nicolas, Pottier, Géraldine, Caillé, Fabien, Coulon, Christine, Goislard, Maud, Jégo, Benoit, Negroni, Julia, Leroy, Claire, Saba, Wadad

“…A large body of preclinical research has shown that neuroimmunity plays a key role in the deleterious effects of alcohol (ethanol) to the brain. Translational…”
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Improved Automated Radiosynthesis of 18FDolutegravir: Toward Clinical Applications by Huvelle, Steve, Pinon, Antoine, Coulon, Christine, Bonasera, Thomas, Chapon, Catherine, Naninck, Thibaut, Le Grand, Roger, Parry, Chris M, Kuhnast, Bertrand, Caillé, Fabien

“…Positron emission tomography imaging using radiolabeled dolutegravir (DTG) is an interesting approach to understand the biodistribution of this antiretroviral…”
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Imaging the neuroimmune response to alcohol exposure in adolescent baboons: a TSPO PET study using ^sup 18^F-DPA-714 by Saba, Wadad, Goutal, Sébastien, Auvity, Sylvain, Kuhnast, Bertrand, Coulon, Christine, Kouyoumdjian, Virginie, Buvat, Irene, Leroy, Claire, Tournier, Nicolas

“…Objectives: The effects of acute alcohol exposure to the central nervous system may not restrict to its interaction with neuronal pathways and may also involve…”
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High specific radioactivity (1R,2S)-4-[ 18F]fluorometaraminol: a PET radiotracer for mapping sympathetic nerves of the heart by Langer, Oliver, Valette, Héric, Dollé, Frédéric, Halldin, Christer, Loc’h, Christian, Fuseau, Chantal, Coulon, Christine, Ottaviani, Michèle, Bottlaender, Michel, Mazière, Bernard, Crouzel, Christian

“…The radiolabeled catecholamine analogue (1R,2S)-6-[ 18F]fluorometaraminol (6-[ 18F]FMR) is a substrate for the neuronal norepinephrine transporter. It has been…”
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[18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106—Selective radioligands for imaging TSPO 18kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls by Kuhnast, Bertrand, Damont, Annelaure, Hinnen, Françoise, Catarina, Tony, Demphel, Stéphane, Le Helleix, Stéphane, Coulon, Christine, Goutal, Sébastien, Gervais, Philippe, Dollé, Frédéric

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Imaging the neuroimmune response to alcohol exposure in adolescent baboons: a TSPO PET study using 18 F-DPA-714 by Saba, Wadad, Goutal, Sébastien, Auvity, Sylvain, Kuhnast, Bertrand, Coulon, Christine, Kouyoumdjian, Virginie, Buvat, Irène, Leroy, Claire, Tournier, Nicolas

“…The effects of acute alcohol exposure to the central nervous system are hypothesized to involve the innate immune system. The neuroimmune response to an…”
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Imaging the neuroimmune response to alcohol exposure in adolescent baboons: a TSPO PET study using [$^{18}$F]DPA-714 by Saba, Wadad, Goutal, Sébastien, Auvity, Sylvain, Kuhnast, Bertrand, Coulon, Christine, Kouyoumdjian, Virginie, Buvat, Irène, Leroy, Claire, Tournier, Nicolas

“…The effects of acute alcohol exposure to the central nervous system are hypothesized to involve the innate immune system. The neuroimmune response to an…”
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Imaging the neuroimmune response to alcohol exposure in adolescent baboons: a TSPO PET study using 18F‐DPA‐714 by Saba, Wadad, Goutal, Sébastien, Auvity, Sylvain, Kuhnast, Bertrand, Coulon, Christine, Kouyoumdjian, Virginie, Buvat, Irène, Leroy, Claire, Tournier, Nicolas

“…The effects of acute alcohol exposure to the central nervous system are hypothesized to involve the innate immune system. The neuroimmune response to an…”
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[ 18F]DPA-714, [ 18F]PBR111 and [ 18F]FEDAA1106—Selective radioligands for imaging TSPO 18 kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls by Kuhnast, Bertrand, Damont, Annelaure, Hinnen, Françoise, Catarina, Tony, Demphel, Stéphane, Le Helleix, Stéphane, Coulon, Christine, Goutal, Sébastien, Gervais, Philippe, Dollé, Frédéric

“…Imaging of TSPO 18 kDa with PET is more and more considered as a relevant biomarker of inflammation in numerous diseases. Development of new radiotracers for…”
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Intravenous infusion for the controlled exposure to the dual ABCB1 and ABCG2 inhibitor elacridar in nonhuman primates by Goutal, Sébastien, Langer, Oliver, Auvity, Sylvain, Andrieux, Karine, Coulon, Christine, Caillé, Fabien, Gervais, Philippe, Cisternino, Salvatore, Declèves, Xavier, Tournier, Nicolas

“…Elacridar (GF120918) is a highly potent inhibitor of both P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2), the main efflux transporters…”
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