Search Results - "COTE, Richard J"
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Adjuvant Chemotherapy for Invasive Bladder Cancer: A 2013 Updated Systematic Review and Meta-Analysis of Randomized Trials
Published in European urology (01-07-2014)“…Abstract Context The role of adjuvant chemotherapy remains poorly defined for the management of muscle-invasive bladder cancer (MIBC). The last meta-analysis…”
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Automatic detection of circulating tumor cells and cancer associated fibroblasts using deep learning
Published in Scientific reports (07-04-2023)“…Circulating tumor cells (CTCs) and cancer-associated fibroblasts (CAFs) from whole blood are emerging as important biomarkers that potentially aid in cancer…”
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Portable Filter-Based Microdevice for Detection and Characterization of Circulating Tumor Cells
Published in Clinical cancer research (15-10-2010)“…Sensitive detection and characterization of circulating tumor cells (CTC) could revolutionize the approach to patients with early-stage and metastatic cancer…”
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3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood
Published in Biomedical microdevices (01-02-2011)“…Detection of circulating tumor cells has emerged as a promising minimally invasive diagnostic and prognostic tool for patients with metastatic cancers. We…”
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Molecular pathogenesis and diagnostics of bladder cancer
Published in Annual review of pathology (01-02-2009)“…Despite elaborate characterization of the risk factors, bladder cancer is still a major epidemiological problem whose incidence continues to rise each year…”
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Molecular Pathways in Invasive Bladder Cancer: New Insights Into Mechanisms, Progression, and Target Identification
Published in Journal of clinical oncology (10-12-2006)“…Papillary and invasive cancers of the urinary bladder appear to evolve and progress through distinct molecular pathways. Invasion in bladder cancer forebodes a…”
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Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b-Mediated Malignant Progression
Published in Cancer research (Chicago, Ill.) (15-01-2016)“…Consequences of the obesity epidemic on cancer morbidity and mortality are not fully appreciated. Obesity is a risk factor for many cancers, but the mechanisms…”
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Phase III Study of Molecularly Targeted Adjuvant Therapy in Locally Advanced Urothelial Cancer of the Bladder Based on p53 Status
Published in Journal of clinical oncology (01-09-2011)“…Retrospective studies suggest that p53 alteration is prognostic for recurrence in patients with urothelial bladder cancer and predictive for benefit from…”
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Most Early Disseminated Cancer Cells Detected in Bone Marrow of Breast Cancer Patients Have a Putative Breast Cancer Stem Cell Phenotype
Published in Clinical cancer research (01-10-2006)“…Purpose: The presence of disseminated tumor cells (DTC) in the bone marrow of breast cancer patients is an acknowledged independent prognostic factor. The…”
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Length-scale study in deep learning prediction for non-small cell lung cancer brain metastasis
Published in Scientific reports (27-09-2024)“…Deep learning-assisted digital pathology has demonstrated the potential to profoundly impact clinical practice, even surpassing human pathologists in…”
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Highly Scalable, Uniform, and Sensitive Biosensors Based on Top-Down Indium Oxide Nanoribbons and Electronic Enzyme-Linked Immunosorbent Assay
Published in Nano letters (11-03-2015)“…Nanostructure field-effect transistor (FET) biosensors have shown great promise for ultra sensitive biomolecular detection. Top-down assembly of these sensors…”
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A Contemporary Update on Pathology Standards for Bladder Cancer: Transurethral Resection and Radical Cystectomy Specimens
Published in European urology (01-02-2013)“…Abstract Context Pathology standards for the diagnosis of bladder cancer (BCa) have recently evolved to better reflect patient diagnosis and clinical outcomes…”
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A Calibration Method for Nanowire Biosensors to Suppress Device-to-Device Variation
Published in ACS nano (22-12-2009)“…Nanowire/nanotube biosensors have stimulated significant interest; however, the inevitable device-to-device variation in the biosensor performance remains a…”
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Multiple biomarkers improve prediction of bladder cancer recurrence and mortality in patients undergoing cystectomy
Published in Cancer (15-01-2008)“…BACKGROUND. Tested was whether the assessment of 5 established bladder cancer biomarkers (p53, pRB, p21, p27, and cyclin E1) could improve the ability to…”
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Disseminated and circulating tumor cells: Role in effective cancer management
Published in Critical reviews in oncology/hematology (01-01-2011)“…Abstract Dissemination of tumor cells from primary tumors in the circulatory system is an early event in carcinogenesis. The presence of these single…”
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Occult Metastases in Lymph Nodes Predict Survival in Resectable Non–Small-Cell Lung Cancer: Report of the ACOSOG Z0040 Trial
Published in Journal of clinical oncology (10-11-2011)“…The survival of patients with non-small-cell lung cancer (NSCLC), even when resectable, remains poor. Several small studies suggest that occult metastases…”
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Importance of Controlling Nanotube Density for Highly Sensitive and Reliable Biosensors Functional in Physiological Conditions
Published in ACS nano (23-11-2010)“…Biosensors utilizing carbon nanotube field-effect transistors have a tremendous potential to serve as the basis for the next generation of diagnostic systems…”
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Bioassay of prostate-specific antigen (PSA) using microcantilevers
Published in Nature biotechnology (01-09-2001)“…Diagnosis and monitoring of complex diseases such as cancer require quantitative detection of multiple proteins. Recent work has shown that when specific…”
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Generation of a Concise Gene Panel for Outcome Prediction in Urinary Bladder Cancer
Published in Journal of clinical oncology (20-08-2009)“…This study sought to determine if alterations in molecular pathways could supplement TNM staging to more accurately predict clinical outcome in patients with…”
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Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival
Published in Human pathology (01-10-2007)“…Summary Chemotherapy resistance is a significant contributor to treatment failure and death in men with hormone-refractory prostate cancer. One unexplored…”
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