Search Results - "COSTELLO, R"

Fore-Giving in Time: A Husserlian Reading of Genesis, Luke, and John by Costello, Peter R.

“…This paper attempts to perform a phenomenology of forgiveness by way of careful analysis of texts on time-consciousness and alterity by Edmund Husserl. It does…”
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Social Media and Substance Use: What Should We Be Recommending to Teens and Their Parents? by Costello, Caitlin R., M.D, Ramo, Danielle E., Ph.D

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'Everything was just getting worse and worse': deteriorating job quality as a driver of doctor emigration from Ireland by Humphries, N, McDermott, A M, Conway, E, Byrne, J-P, Prihodova, L, Costello, R, Matthews, A

“…Medicine is a high-status, high-skill occupation which has traditionally provided access to good quality jobs and relatively high salaries. In Ireland,…”
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ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment by Pérez-Alea, M, McGrail, K, Sánchez-Redondo, S, Ferrer, B, Fournet, G, Cortés, J, Muñoz, E, Hernandez-Losa, J, Tenbaum, S, Martin, G, Costello, R, Ceylan, I, Garcia-Patos, V, Recio, J A

“…Despite the promising targeted and immune-based interventions in melanoma treatment, long-lasting responses are limited. Melanoma cells present an aberrant…”
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Magnetic resonance imaging of tumor response to stroma-modifying pegvorhyaluronidase alpha (PEGPH20) therapy in early-phase clinical trials by Arias-Lorza, Andrés M., Costello, James R., Hingorani, Sunil R., Von Hoff, Daniel D., Korn, Ronald L., Raghunand, Natarajan

“…Pre-clinical and clinical studies have shown that PEGPH20 depletes intratumoral hyaluronic acid (HA), which is linked to high interstitial fluid pressures and…”
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Bridging cell-scale simulations and radiologic images to explain short-time intratumoral oxygen fluctuations by Kingsley, Jessica L, Costello, James R, Raghunand, Natarajan, Rejniak, Katarzyna A

“…Radiologic images provide a way to monitor tumor development and its response to therapies in a longitudinal and minimally invasive fashion. However, they…”
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Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the PRe-clinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort by Costello, R E, Humphreys, J H, Sergeant, J C, Haris, M, Stirling, F, Raza, K, van Schaardenburg, D, Bruce, Ian N

“…First-degree relatives (FDRs) of people with rheumatoid arthritis (RA) have a fourfold increased risk of developing RA. The Symptoms in Persons At Risk of…”
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Incidence and Risk Factors for Gadolinium-Based Contrast Agent Immediate Reactions by Costello, James R, Kalb, Bobby, Martin, Diego R

“…ABSTRACTSince their clinical introduction in 1988, gadolinium-based contrast agents (GBCAs) have demonstrated an excellent safety profile with a reported acute…”
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Paediatric quality-of-life following adenotonsillectomy: an evaluation of T14 paediatric throat disorder quality-of-life outcomes according to operative indication by Puttasiddaiah, P M, Morris, S, Costello, R C, Whittet, H B

“…Adenotonsillectomy is the most common surgical intervention for obstructive sleep apnoea (OSA) or recurrent tonsillitis. The Paediatric Throat Disorder Quality…”
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Deer on the lookout: how hunting, hiking and coyotes affect white‐tailed deer vigilance by Schuttler, S. G., Parsons, A. W., Forrester, T. D., Baker, M. C., McShea, W. J., Costello, R., Kays, R.

“…Predators affect prey directly by removing animals from the population and indirectly by modifying prey behavior. Humans have extirpated apex predators from…”
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Reactive oxygen species and aldehyde dehydrogenase 1A as prognosis and theragnostic biomarker in acute myeloid leukaemia patients by Venton, G., Colle, J., Tichadou, A., Quessada, J., Baier, C., Labiad, Y., Perez, M., De Lassus, L., Loosveld, M., Arnoux, I., Abbou, N., Ceylan, I., Martin, G., Costello, R.

“…Acute myeloid leukaemia (AML) remains a major unmet medical, despite recent progress in targeted molecular therapies. One aspect of leukaemic cell resistance…”
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Correction to: Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the Preclinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort by Costello, R E, Humphreys, J H, Sergeant, J C, Haris, M, Stirling, F, Raza, K, van Schaardenburg, D, Bruce, Ian N

“…An amendment to this paper has been published and can be accessed via the original article…”
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Racial disparities in the prevalence of monoclonal gammopathies: a population-based study of 12 482 persons from the National Health and Nutritional Examination Survey by Landgren, O, Graubard, B I, Katzmann, J A, Kyle, R A, Ahmadizadeh, I, Clark, R, Kumar, S K, Dispenzieri, A, Greenberg, A J, Therneau, T M, Melton, L J, Caporaso, N, Korde, N, Roschewski, M, Costello, R, McQuillan, G M, Rajkumar, S V

“…Multiple myeloma (MM) incidence is markedly higher in blacks compared with whites, which may be related to a higher prevalence of monoclonal gammopathy of…”
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Aldehyde dehydrogenases inhibition eradicates leukemia stem cells while sparing normal progenitors by Venton, G, Pérez-Alea, M, Baier, C, Fournet, G, Quash, G, Labiad, Y, Martin, G, Sanderson, F, Poullin, P, Suchon, P, Farnault, L, Nguyen, C, Brunet, C, Ceylan, I, Costello, R T

“…The vast majority of patients with acute myeloid leukemia (AML) achieve complete remission (CR) after standard induction chemotherapy. However, the majority…”
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Multivariate genetic architecture of the Anolis dewlap reveals both shared and sex‐specific features of a sexually dimorphic ornament by Cox, R. M., Costello, R. A., Camber, B. E., McGlothlin, J. W.

“…Darwin viewed the ornamentation of females as an indirect consequence of sexual selection on males and the transmission of male phenotypes to females via the…”
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Inhibition of DNMT1 methyltransferase activity via glucose-regulated O -GlcNAcylation alters the epigenome by Shin, Heon, Leung, Amy, Costello, Kevin R, Senapati, Parijat, Kato, Hiroyuki, Moore, Roger E, Lee, Michael, Lin, Dimitri, Tang, Xiaofang, Pirrotte, Patrick, Bouman Chen, Zhen, Schones, Dustin E

“…The DNA methyltransferase activity of DNMT1 is vital for genomic maintenance of DNA methylation. We report here that DNMT1 function is regulated by…”
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High incidence of CDA deficiency in patients with hematological malignancies: perspectives and therapeutic implications by Donnette, M., Ciccolini, J., Pissier, C., Costello, R., Duffaud, F., Salas, S., Farnault, L., Tichadou, A., Arcani, R., Jarrot, P.A., Ouafik, L.H., Venton, G., Fanciullino, R.

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Screening for lung cancer using low dose CT scanning by MacRedmond, R, Logan, P M, Lee, M, Kenny, D, Foley, C, Costello, R W

“…Background: Lung cancer is the most common cause of cancer related death in Ireland. The majority of lung cancers are inoperable at the time of diagnosis and…”
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The impact of change of renal replacement therapy modality on sleep quality in patients with end-stage renal disease: a systematic review and meta-analysis by Kennedy, C., Ryan, S. A., Kane, T., Costello, R. W., Conlon, P. J.

“…Background Sleep disorders are common and multi-factorial in patients with advanced chronic kidney disease and end-stage renal disease (ESRD). Sleep disorders…”
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Sequence features of retrotransposons allow for epigenetic variability by Costello, Kevin R, Leung, Amy, Trac, Candi, Lee, Michael, Basam, Mudaser, Pospisilik, J Andrew, Schones, Dustin E

“…Transposable elements (TEs) are mobile genetic elements that make up a large fraction of mammalian genomes. While select TEs have been co-opted in host genomes…”
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