Search Results - "COSIMO, E"

Complement deficiencies limit CD20 monoclonal antibody treatment efficacy in CLL by Middleton, O, Cosimo, E, Dobbin, E, McCaig, A M, Clarke, C, Brant, A M, Leach, M T, Michie, A M, Wheadon, H

“…Monoclonal antibodies (MAbs) form a central part of chronic lymphocytic leukaemia (CLL) treatment. We therefore evaluated whether complement defects in CLL…”
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p21 -mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy by MCCARTHY, H. O, WORTHINGTON, J, BARRETT, E, COSIMO, E, BOYD, M, MAIRS, R. J, WARD, C, MCKEOWN, S. R, HIRST, D. G, ROBSON, T

“…Cancer gene therapy that utilizes toxic transgene products requires strict transcriptional targeting to prevent adverse normal tissue effects. We report on the…”
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Anti-GD2 monoclonal antibody immunotherapy: a promising strategy in the prevention of neuroblastoma relapse by Raffaghello, L., Marimpietri, D., Pagnan, G., Pastorino, F., Cosimo, E., Brignole, C., Ponzoni, M., Montaldo, P.G.

“…In spite of the satisfactory frequency of clinical response to first-line therapy in neuroblastoma (NB), complete eradication of NB cells is rarely achieved…”
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Immunoliposomal fenretinide: a novel antitumoral drug for human neuroblastoma by Raffaghello, L., Pagnan, G., Pastorino, F., Cosimo, E., Brignole, C., Marimpietri, D., Bogenmann, E., Ponzoni, M., Montaldo, P.G.

“…Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. In advanced disease stages, prognosis is poor and treatments have limited…”
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Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKC  subversion induces up-regulation of PKC II expression in B lymphocytes by Nakagawa, R., Vukovic, M., Tarafdar, A., Cosimo, E., Dunn, K., McCaig, A. M., Holroyd, A., McClanahan, F., Ramsay, A. G., Gribben, J. G., Michie, A. M.

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Targeted delivery system for antisense oligonucleotides: a novel experimental strategy for neuroblastoma treatment by Brignole, Chiara, Pagnan, Gabriella, Marimpietri, Danilo, Cosimo, Emilio, Allen, Theresa M., Ponzoni, Mirco, Pastorino, Fabio

“…Neuroblastoma (NB) is the most common neuroectoderma derived solid tumour of paediatric age. Since conventional treatments are often inefficient, novel…”
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Gaps in urinary incontinence rehabilitation after radical prostatectomy by Pelizzari, Laura, Lombardo, Riccardo, DE Cillis, Sabrina, Giammo, Alessandro, Li Marzi, Vincenzo, DE Nunzio, Cosimo

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Reelin expression in breast tumours is associated with increased survival and is controlled by promoter methylation by Stein, T, Cosimo, E, Smith, P, Simon, R, Price, K, Baird, L, Bell, AK, Sauter, G, Crook, T, Gusterson, BA

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In vitro and in vivo antitumor activity of liposomal fenretinide targeted to human neuroblastoma by Raffaghello, Lizzia, Pagnan, Gabriella, Pastorino, Fabio, Cosimo, Emilio, Brignole, Chiara, Marimpietri, Danilo, Montaldo, Paolo G., Gambini, Claudia, Allen, Theresa M., Bogenmann, Emil, Ponzoni, Mirco

“…Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. In advanced disease stages, prognosis is poor and treatments have limited…”
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Inhibition of neuroblastoma‐induced angiogenesis by fenretinide by Ribatti, Domenico, Alessandri, Giulio, Baronio, Manuela, Raffaghello, Lizzia, Cosimo, Emilio, Marimpietri, Danilo, Montaldo, Paolo Giuseppe, De Falco, Giuseppe, Caruso, Arnaldo, Vacca, Angelo, Ponzoni, Mirco

“…Retinoids are a class of natural or synthetic compounds that participate in the control of cell proliferation, differentiation and fetal development. The…”
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p21 super((WAF1))-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy by McCarthy, HO, Worthington, J, Barrett, E, Cosimo, E, Boyd, M, Mairs, R J, Ward, C, McKeown, SR, Hirst, D G, Robson, T

“…Cancer gene therapy that utilizes toxic transgene products requires strict transcriptional targeting to prevent adverse normal tissue effects. We report on the…”
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Prostate cancer diagnostic pathway in men with lower urinary tract symptoms or performing opportunistic screening: The Italian Society of Urology (SIU) position paper by Ficarra, Vincenzo, Bartoletti, Riccardo, Borghesi, Marco, DE Nunzio, Cosimo, Falagario, Ugo G, Gandaglia, Giorgio, Giannarini, Gianluca, Minervini, Andrea, Mirone, Vincenzo, Porpiglia, Francesco, Rocco, Bernardo, Salonia, Andrea, Verze, Paolo, Carrieri, Giuseppe

“…Voluntary PCa screening frequently results in excessive use of unnecessary diagnostic tests and an increasing risk of detection of indolent PCa and…”
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Organized prostate cancer screening program: a proposal from the Italian Society of Urology (SIU) by Ficarra, Vincenzo, Bartoletti, Riccardo, Borghesi, Marco, Caffo, Orazio, DE Nunzio, Cosimo, Falagario, Ugo G, Gandaglia, Giorgio, Giannarini, Gianluca, Minervini, Andrea, Mirone, Vincenzo, Porpiglia, Francesco, Rocco, Bernardo, Salonia, Andrea, Verze, Paolo, Carrieri, Giuseppe

“…To contrast opportunistic PCa screening, the European Union Council suggested extending screening programs to PCa by recommending the implementation of a…”
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Ultrasound assessment of intravesical prostatic protrusion and detrusor wall thickness--new standards for noninvasive bladder outlet obstruction diagnosis? by Franco, Giorgio, De Nunzio, Cosimo, Leonardo, Costantino, Tubaro, Andrea, Ciccariello, Mauro, De Dominicis, Carlo, Miano, Lucio, Laurenti, Cesare

“…We evaluated the accuracy of detrusor wall thickness and intravesical prostatic protrusion, and the association of each test to diagnose bladder prostatic…”
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Postoperative urinary incontinence following BPH surgery: insights from a comprehensive national database analysis by Licari, Leslie C, Bologna, Eugenio, Manfredi, Celeste, Franco, Antonio, Ditonno, Francesco, DE Nunzio, Cosimo, Franco, Giorgio, Cindolo, Luca, Leonardo, Costantino, Adelstein, Sarah A, Fiori, Cristian, Cherullo, Edward E, Olweny, Ephrem O, Autorino, Riccardo

“…Postoperative urinary incontinence (UI) is a feared complication of BPH surgery. Our study aims to investigate the incidence of UI among patients undergoing…”
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Gene manipulation to enhance MIBG-targeted radionuclide therapy by Mairs, Robert J., Fullerton, Natasha E., Cosimo, Emilio, Boyd, Marie

“…The goal of targeted radionuclide therapy is the deposition in malignant cells of sterilizing doses of radiation without damaging normal tissue. The…”
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The function of alkaline phosphatase in the liver: Regulation of intrahepatic biliary epithelium secretory activities in the rat by Alvaro, Domenico, Benedetti, Antonio, Marucci, Luca, Delle Monache, Marco, Monterubbianesi, Rita, Di Cosimo, Emanuele, Perego, Lucia, Macarri, Giampiero, Glaser, Shannon, Le Sage, Gene, Alpini, Gianfranco

“…We studied the effects of alkaline phosphatase (AP) on the secretory processes of the rat intrahepatic biliary epithelium as well as the role of the…”
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Fenretinide as an anti-angiogenic agent in neuroblastoma by Ribatti, Domenico, Raffaghello, Lizzia, Marimpietri, Danilo, Cosimo, Emilio, Montaldo, P.Giuseppe, Nico, Beatrice, Vacca, Angelo, Ponzoni, Mirco

“…Angiogenesis is a critical event in the progression of human neuroblastoma. This mini-review summarizes our literature and experimental data concerning the use…”
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Immunoliposomal fenretinide: a novel antitumoral drug for human neuroblastoma: Neuroblastoma - Developmental and molecular biology meet therapy design by RAFFAGHELLO, L, PAGNAN, G, PASTORINO, F, COSIMO, E, BRIGNOLE, C, MARIMPIETRI, D, BOGENMANN, E, PONZONI, M, MONTALDO, P. G

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Anti-GD2 monoclonal antibody immunotherapy: a promising strategy in the prevention of neuroblastoma relapse: Neuroblastoma - Developmental and molecular biology meet therapy design by RAFLAGHELLO, L, MARIMPIETRI, D, PAGNAN, G, PASTORINO, F, COSIMO, E, BRIGNOLE, C, PONZONI, M, MONTALDO, P. G

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