Search Results - "COPPEDE, Fabio"

One-carbon epigenetics and redox biology of neurodegeneration by Coppedè, Fabio

“…One-carbon metabolism provides the methyl groups for both DNA and histone tail methylation reactions, two of the main epigenetic processes that tightly…”
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Mitochondrial DNA Methylation and Human Diseases by Stoccoro, Andrea, Coppedè, Fabio

“…Epigenetic modifications of the nuclear genome, including DNA methylation, histone modifications and non-coding RNA post-transcriptional regulation, are…”
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Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics by Migliore, Lucia, Coppedè, Fabio

“…With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex aetiology that is likely to involve multiple susceptibility genes and…”
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Risk factors for Down syndrome by Coppede, Fabio

“…Down syndrome (DS) originates, in most of the cases (95 %), from a full trisomy of chromosome 21. The remaining cases are due to either mosaicism for…”
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DNA methylation in amyotrophic lateral sclerosis: where do we stand and what is next? by Coppedè, Fabio

“…Genes involved in immune response, inflammation and metabolism are among those most likely affected by changes in DNA methylation (DNAm) and expression levels…”
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Genetic and epigenetic biomarkers for diagnosis, prognosis and treatment of colorectal cancer by Fabio Coppedè Angela Lopomo Roberto Spisni Lucia Migliore

“…Colorectal cancer(CRC)is one of the most common cancer worldwide and results from the accumulation of mutations and epimutations in colonic mucosa cells…”
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Genes and the Environment in Cancer: Focus on Environmentally Induced DNA Methylation Changes by Coppedè, Fabio

“…Cancer has traditionally been viewed as a genetic disorder resulting from the accumulation of gene mutations, chromosomal rearrangements, and aneuploidies in…”
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Cancer Epigenetic Biomarkers by Coppedè, Fabio

“…This series of nine articles (six original articles, three reviews) is presented by international experts in cancer epigenetics [...]…”
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Epigenetics of neuromuscular disorders by Coppedè, Fabio

“…Neuromuscular disorders are a heterogeneous group of conditions affecting the neuromuscular system. The aim of this article is to review the major epigenetic…”
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25 Years of Current Genomics by Fabio Coppedè

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DNA methylation as a powerful tool to investigate the biology and pathology of aging by Coppedè, Fabio

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Mitochondrial DNA methylation and mitochondria-related epigenetics in neurodegeneration by Coppedè, Fabio

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Special Issue “Genetics and Epigenetics of Neuromuscular Diseases” by Coppedè, Fabio

“…Neuromuscular disorders (NMDs) include several hereditary or acquired conditions that impair the neuromuscular system and muscle function [...]…”
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The diagnostic potential of the epigenome in autism spectrum disorders by Coppedè, Fabio

“…The diagnostic application of genome-wide methylation signatures is increasing in various syndromic forms of autism, but further studies are warranted to…”
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Targeting the epigenome to treat neurodegenerative diseases or delay their onset: a perspective by Coppede, Fabio

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Mitoepigenetics and Neurodegenerative Diseases by Coppedè, Fabio, Stoccoro, Andrea

“…Mitochondrial impairment and increased oxidative stress are common features in neurodegenerative disorders, leading researchers to speculate that epigenetic…”
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Epigenetic biomarkers of colorectal cancer: Focus on DNA methylation by Coppedè, Fabio

“…Abstract The original theory of the multi-step process of colorectal cancer (CRC), suggesting that the disease resulted from the accumulation of mutations in…”
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DNA damage in neurodegenerative diseases by Coppedè, Fabio, Migliore, Lucia

“…Following the observation of increased oxidative DNA damage in nuclear and mitochondrial DNA extracted from post-mortem brain regions of patients affected by…”
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Genetics and Epigenetics of Parkinson's Disease by Coppede, Fabio

“…In 1997 a mutation in the a-synuclein (SNCA) gene was associated with familial autosomal dominant Parkinson’s disease (PD). Since then, several loci (PARK1-15)…”
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Epigenetics and Autoimmune Thyroid Diseases by Coppedè, Fabio

“…Increasing evidence suggests that epigenetic modifications, including changes in DNA methylation, covalent modifications of histone tails, and gene silencing…”
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