Search Results - "COOPER, C. D"

DAT isn’t all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling by Northcutt, A L, Hutchinson, M R, Wang, X, Baratta, M V, Hiranita, T, Cochran, T A, Pomrenze, M B, Galer, E L, Kopajtic, T A, Li, C M, Amat, J, Larson, G, Cooper, D C, Huang, Y, O'Neill, C E, Yin, H, Zahniser, N R, Katz, J L, Rice, K C, Maier, S F, Bachtell, R K, Watkins, L R

“…The initial reinforcing properties of drugs of abuse, such as cocaine, are largely attributed to their ability to activate the mesolimbic dopamine system…”
Get full text

Statistical Analysis of APXS‐Derived Chemistry of the Clay‐Bearing Glen Torridon Region and Mount Sharp Group, Gale Crater, Mars by O’Connell‐Cooper, C. D., Thompson, L. M., Spray, J. G., Berger, J. A., Gellert, R., McCraig, M., VanBommel, S. J., Yen, A.

“…The Glen Torridon stratigraphic sequence marks the transition from the low energy lacustrine‐dominated Murray formation (Mf) (Jura member: Jm) to the more…”
Get full text

Formation of Tridymite and Evidence for a Hydrothermal History at Gale Crater, Mars by Yen, A. S., Morris, R. V., Ming, D. W., Schwenzer, S. P., Sutter, B., Vaniman, D. T., Treiman, A. H., Gellert, R., Achilles, C. N., Berger, J. A., Blake, D. F., Boyd, N. I., Bristow, T. F., Chipera, S., Clark, B. C., Craig, P. I., Downs, R. T., Franz, H. B., Gabriel, T., McAdam, A. C., Morrison, S. M., O’Connell‐Cooper, C. D., Rampe, E. B., Schmidt, M. E., Thompson, L. M., VanBommel, S. J.

“…In August 2015, the Curiosity Mars rover discovered tridymite, a high‐temperature silica polymorph, in Gale crater. The existing model for its occurrence…”
Get full text

APXS‐Derived Compositional Characteristics of Vera Rubin Ridge and Murray Formation, Gale Crater, Mars: Geochemical Implications for the Origin of the Ridge by Thompson, L. M., Berger, J. A., Spray, J. G., Fraeman, A. A., McCraig, M. A., O'Connell‐Cooper, C. D., Schmidt, M. E., VanBommel, S., Gellert, R., Yen, A., Boyd, N. I.

“…The resistant ~50 m thick Vera Rubin ridge (VRR) situated near the base of Mount Sharp, Gale crater, Mars, has been deemed a high priority science target for…”
Get full text

MicroRNA expression in lymphocyte development and malignancy by Lawrie, C H, Saunders, N J, Soneji, S, Palazzo, S, Dunlop, H M, Cooper, C D O, Brown, P J, Troussard, X, Mossafa, H, Enver, T, Pezzella, F, Boultwood, J, Wainscoat, J S, Hatton, C S R

Get full text

Chemical Diversity of Sands Within the Linear and Barchan Dunes of the Bagnold Dunes, Gale Crater, as Revealed by APXS Onboard Curiosity by O'Connell‐Cooper, C. D., Thompson, L. M., Spray, J. G., Berger, J. A., VanBommel, S. J., Gellert, R., Boyd, N. I., DeSouza, E.

“…Alpha Particle X‐ray Spectrometer (APXS) results for Phase 2 of the Bagnold Dunes campaign, focusing on the linear dunes, complement those from Phase 1…”
Get full text

Manganese Mobility in Gale Crater, Mars: Leached Bedrock and Localized Enrichments by Berger, J. A., King, P. L., Gellert, R., Clark, B. C., Flood, V. A., McCraig, M. A., Ming, D. W., O’Connell‐Cooper, C. D., Schmidt, M. E., Thompson, L. M., VanBommel, S. J. V., Wilhelm, B., Yen, A. S.

“…In Gale crater on Mars, the rover Curiosity has discovered evidence of fluid mobilization of the redox‐sensitive element manganese. We present results for Mn…”
Get full text

APXS‐derived chemistry of the Bagnold dune sands: Comparisons with Gale Crater soils and the global Martian average by O'Connell‐Cooper, C. D., Spray, J. G., Thompson, L. M., Gellert, R., Berger, J. A., Boyd, N. I., Desouza, E. D., Perrett, G. M., Schmidt, M., VanBommel, S. J.

“…We present Alpha‐Particle X‐ray Spectrometer (APXS) data for the active Bagnold dune field within the Gale impact crater (Mars Science Laboratory (MSL)…”
Get full text

Metabolic aspects of pig-to-monkey (Macaca fascicularis) islet transplantation: implications for translation into clinical practice by Casu, A, Bottino, R, Balamurugan, A. N, Hara, H, van der Windt, D. J, Campanile, N, Smetanka, C, Cooper, D. K. C, Trucco, M

“…Aims/hypothesis Attempts to use an alternative source of islets to restore glucose homeostasis in diabetic patients require preclinical islet…”
Get full text

DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission by Fienberg, A. A., Hiroi, N., Mermelstein, P. G., W.-J. Song, Snyder, G. L., Nishi, A., Cheramy, A., O'Callaghan, J. P., Miller, D. B., Cole, D. G., Corbett, R., Haile, C. N., Cooper, D. C., Onn, S. P., Grace, A. A., Ouimet, C. C., White, F. J., Hyman, S. E., Surmeier, D. J., J.-A. Girault, Nestler, E. J., Greengard, P.

“…Dopaminergic neurons exert a major modulatory effect on the forebrain. Dopamine and adenosine 3′,5′-monophosphate-regulated phosphoprotein (32 kilodaltons)…”
Get full text

Evidence for recent climate change on Mars from the identification of youthful near-surface ground ice by Mustard, John F, Cooper, Christopher D, Rifkin, Moses K

“…Ground ice in the crust and soil may be one of the largest reservoirs of water on Mars. Near-surface ground ice is predicted to be stable at latitudes higher…”
Get full text

Predicting QT prolongation in humans during early drug development using hERG inhibition and an anaesthetized guinea‐pig model by Yao, X, Anderson, D L, Ross, S A, Lang, D G, Desai, B Z, Cooper, D C, Wheelan, P, McIntyre, M S, Bergquist, M L, MacKenzie, K I, Becherer, J D, Hashim, M A

“…Background and purpose: Drug‐induced prolongation of the QT interval can lead to torsade de pointes, a life‐threatening ventricular arrhythmia. Finding…”
Get full text

Xenotransplantation—the current status and prospects by Cooper, D K C, Gaston, R, Eckhoff, D, Ladowski, J, Yamamoto, T, Wang, L, Iwase, H, Hara, H, Tector, M, Tector, A J

“…Abstract Introduction There is a continuing worldwide shortage of organs from deceased human donors for transplantation into patients with end-stage organ…”
Get full text

Red Water Release in Drinking Water Distribution Systems by IMRAN, SYED A., DIETZ, JOHN D., MUTOTI, GINASIYO, TAYLOR, JAMES S., RANDALL, ANDREW A., COOPER, C.D.

“…The implementation of groundwater conservation measures has forced utilities with a historical reliance on groundwater sources to consider alternative sources…”
Get full text

Long‐Term Controlled Normoglycemia in Diabetic Non‐Human Primates After Transplantation with hCD46 Transgenic Porcine Islets by Van Der Windt, D. J., Bottino, R., Casu, A., Campanile, N., Smetanka, C., He, J., Murase, N., Hara, H., Ball, S., Loveland, B. E, Ayares, D., Lakkis, F. G., Cooper, D. K. C., Trucco, M.

“…Xenotransplantation of porcine islets into diabetic non‐human primates is characterized by (i) an initial massive graft loss possibly due to the instant…”
Get full text

Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft Recipients by Ezzelarab, M. B., Zhang, H., Guo, H., Lu, L., Zahorchak, A. F., Wiseman, R. W., Nalesnik, M. A., Bhama, J. K., Cooper, D. K. C., Thomson, A. W.

“…The ability of regulatory T cells (Treg) to prolong allograft survival and promote transplant tolerance in lymphodepleted rodents is well established. Few…”
Get full text

Regulatory Dendritic Cell Infusion Prolongs Kidney Allograft Survival in Nonhuman Primates by Ezzelarab, M. B., Zahorchak, A. F., Lu, L., Morelli, A. E., Chalasani, G., Demetris, A. J., Lakkis, F. G., Wijkstrom, M., Murase, N., Humar, A., Shapiro, R., Cooper, D. K. C., Thomson, A. W.

“…We examined the influence of regulatory dendritic cells (DCreg), generated from cytokine‐mobilized donor blood monocytes in vitamin D3 and IL‐10, on renal…”
Get full text

PASD1, a DLBCL-associated cancer testis antigen and candidate for lymphoma immunotherapy by COOPER, C. D. O, LIGGINS, A. P, AIT-TAHAR, K, RONCADOR, G, BANHAM, A. H, PULFORD, K

Get full text

Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen‐induced arthritis by Willis, V. C., Banda, N. K., Cordova, K. N., Chandra, P. E., Robinson, W. H., Cooper, D. C., Lugo, D., Mehta, G., Taylor, S., Tak, P. P., Prinjha, R. K., Lewis, H. D., Holers, V. M.

“…Summary Citrullination of joint proteins by the protein arginine deiminase (PAD) family of enzymes is recognized increasingly as a key process in the…”
Get full text

Recipient Tissue Factor Expression Is Associated With Consumptive Coagulopathy in Pig‐to‐Primate Kidney Xenotransplantation by Lin, C. C., Ezzelarab, M., Shapiro, R., Ekser, B., Long, C., Hara, H., Echeverri, G., Torres, C., Watanabe, H., Ayares, D., Dorling, A., Cooper, D. K. C.

“…Consumptive coagulopathy (CC) remains a challenge in pig‐to‐primate organ xenotransplantation (Tx). This study investigated the role of tissue factor (TF)…”
Get full text