Search Results - "COOLEY, Margaret"

Structure of a mitochondrial cytochrome c conformer competent for peroxidase activity by McClelland, Levi J., Mou, Tung-Chung, Jeakins-Cooley, Margaret E., Sprang, Stephen R., Bowler, Bruce E.

“…At the onset of apoptosis, the peroxidation of cardiolipin at the inner mitochondrial membrane by cytochrome c requires an open coordination site on the heme…”
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High peripheral blood th17 percent associated with poor lung function in cystic fibrosis by Mulcahy, Emily M, Hudson, Jo B, Beggs, Sean A, Reid, David W, Roddam, Louise F, Cooley, Margaret A

“…People with cystic fibrosis (CF) have been reported to make lung T cell responses that are biased towards T helper (Th) 2 or Th17. We hypothesized that…”
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Expression of PPARγ and paraoxonase 2 correlated with Pseudomonas aeruginosa infection in cystic fibrosis by Griffin, Phoebe E, Roddam, Louise F, Belessis, Yvonne C, Strachan, Roxanne, Beggs, Sean, Jaffe, Adam, Cooley, Margaret A

“…The Pseudomonas aeruginosa quorum sensing signal molecule N-3-oxododecanoyl-l-homoserine lactone (3OC(12)HSL) can inhibit function of the mammalian…”
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Pseudomonas signal molecule 3-oxo-C12-homoserine lactone interferes with binding of rosiglitazone to human PPARγ by Cooley, Margaret A., Whittall, Christine, Rolph, Michael S.

“…Peroxisome proliferator activated receptor (PPARγ) has been suggested as a target for anti-inflammatory therapy in chronic lung disease, including infection…”
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Disruption of a hydrogen bond network in human versus spider monkey cytochrome c affects heme crevice stability by Goldes, Matthew E., Jeakins-Cooley, Margaret E., McClelland, Levi J., Mou, Tung-Chung, Bowler, Bruce E.

“…The hypothesis that the recent rapid evolution of primate cytochromes c, which primarily involves residues in the least stable Ω-loop (Ω-loop C, residues…”
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A quadruple knockout of lasIR and rhlIR of Pseudomonas aeruginosa PAO1 that retains wild-type twitching motility has equivalent infectivity and persistence to PAO1 in a mouse model of lung infection by Lazenby, James J, Griffin, Phoebe E, Kyd, Jennelle, Whitchurch, Cynthia B, Cooley, Margaret A

“…It has been widely reported that quorum-sensing incapable strains of Pseudomonas aeruginosa are less virulent than wild type strains. However, quorum sensing…”
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Widespread alterations in the peripheral blood innate immune cell profile in cystic fibrosis reflect lung pathology by Mulcahy, Emily M, Cooley, Margaret A, McGuire, Helen, Asad, Suzanne, Fazekas de St Groth, Barbara, Beggs, Sean A, Roddam, Louise F

“…Cystic fibrosis (CF) is caused by mutations to the CF transmembrane conductance regulator (CFTR) gene. CFTR is known to be expressed on multiple immune cell…”
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Impaired Insulin Secretion in the Turner Metabolic Syndrome by Bakalov, Vladimir K., Cooley, Margaret M., Quon, Michael J., Luo, Mei Lin, Yanovski, Jack A., Nelson, Lawrence M., Sullivan, Gail, Bondy, Carolyn A.

“…An increased prevalence of impaired glucose homeostasis (IGH) and diabetes mellitus is reported in monosomy X, or Turner syndrome (TS). To determine whether…”
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The immunomodulatory Pseudomonas aeruginosa signalling molecule N‐(3‐oxododecanoyl)‐l‐homoserine lactone enters mammalian cells in an unregulated fashion by Ritchie, Adam J, Whittall, Christine, Lazenby, James J, Chhabra, Siri Ram, Pritchard, David I, Cooley, Margaret A

“…The Pseudomonas aeruginosa quorum‐sensing signal molecule N‐3‐oxododecanoyl)‐l‐homoserine lactone (OdDHL) has been reported to affect the function of a wide…”
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Modification of In Vivo and In Vitro T- and B-Cell-Mediated Immune Responses by the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone by RITCHIE, Adam J, YAM, Andrew O. W, TANABE, Kara M, RICE, Scott A, COOLEY, Margaret A

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cyclophosphamide augments inflammation by reducing immunosuppression in a mouse model of allergic airway disease by Su, Yung-Chang, Rolph, Michael S., Cooley, Margaret A., Sewell, William A.

“…Allergic asthma is a T H2 cell–driven immunological disease, characterized by eosinophilic inflammation. The cytotoxic agent cyclophosphamide paradoxically…”
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In silico simulations suggest that Th‐cell development is regulated by both selective and instructive mechanisms by Jansson, Andreas, Fagerlind, Magnus, Karlsson, Diana, Nilsson, Patric, Cooley, Margaret

“…Th‐cell differentiation is highly influenced by the local cytokine environment. Although cytokines such as IL‐12 and IL‐4 are known to polarize the Th‐cell…”
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The prevalence of diabetes mellitus in the parents of women with Turner's syndrome by Bakalov, Vladimir K., Cooley, Margaret M., Troendle, James, Bondy, Carolyn A.

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N-Acylhomoserine Lactone-Mediated Quorum Sensing: A Twist in the Tail and a Blow for Host Immunity by Cooley, Margaret, Chhabra, Siri Ram, Williams, Paul

“…Communication through quorum sensing (QS) enables bacterial populations to coordinate their behavior. Recent work on N-acylhomoserine lactone-mediated QS has…”
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Major vascular anomalies in turner syndrome: Prevalence and magnetic resonance angiographic features by HO, Vincent B, BAKALOV, Vladimir K, COOLEY, Margaret, VAN, Phillip L, HOOD, Maureen N, BURKLOW, Thomas R, BONDY, Carolyn A

“…Turner syndrome (TS) is associated with aortic coarctation and dissection; hence, echocardiographic evaluation of all patients is currently recommended. X-ray…”
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Alternative Conformations of Yeast Iso-1-Cytochrome C: Effects of a Gatekeeping Residue on Heme Crevice Dynamics by McClelland, Levi J., Mou, Tung-Chung, Jeakins-Cooley, Margaret E., Cherney, Melisa M., Sprang, Stephen R., Bowler, Bruce E.

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Mast cells in the rat liver are phenotypically heterogeneous and exhibit features of immaturity by Chan, Antonio, Cooley, Margaret A, Collins, Andrew M

“…Gastrointestinal hypersensitivity to food allergens is a significant but relatively poorly understood allergic disease. Recent evidence from a rat model of…”
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How students from non-dominant cultures perceive their social and cultural experiences in relation to school success by Cooley, Margaret

“…This study explores the shared narratives of males who are African American, come from low-income families, struggled with school success, and may have been…”
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Expression of PPAR[gamma] and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis by Griffin, Phoebe E, Roddam, Louise F, Belessis, Yvonne C, Strachan, Roxanne, Beggs, Sean, Jaffe, Adam, Cooley, Margaret A

“…The Pseudomonas aeruginosa quorum sensing signal molecule N-3-oxododecanoyl-l-homoserine lactone (3OC.sub.12 HSL) can inhibit function of the mammalian…”
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Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation by Skindersoe, Mette E, Zeuthen, Louise H, Brix, Susanne, Fink, Lisbeth N, Lazenby, James, Whittall, Christine, Williams, Paul, Diggle, Stephen P, Froekiaer, Hanne, Cooley, Margaret, Givskov, Michael

“…Pseudomonas aeruginosa releases a wide array of toxins and tissue-degrading enzymes. Production of these malicious virulence factors is controlled by…”
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