Search Results - "COOKE, J. P"

Endogenous nitric oxide synthase inhibitor : A novel marker of atherosclerosis by MIYAZAKI, H, MATSUOKA, H, COOKE, J. P, USUI, M, UEDA, S, OKUDA, S, IMAIZUMI, T

“…Exposure to risk factors such as hypertension or hypercholesterolemia decreases the bioavailability of endothelium-derived nitric oxide (NO) and impairs…”
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Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes by Asagami, T., Abbasi, F., Stuelinger, M., Lamendola, C., McLaughlin, T., Cooke, J.P., Reaven, G.M., Tsao, P.S.

“…This study was initiated to see if plasma asymmetric dimethylarginine (ADMA) concentrations decreased in hyperglycemic patients with type 2 diabetes following…”
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Novel mechanism for endothelial dysfunction dysregulation of dimethylarginine dimethylaminohydrolase by ITO, A, TSAO, P. S, ADIMOOLAM, S, KIMOTO, M, OGAWA, T, COOKE, J. P

“…Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS). Plasma levels of ADMA are elevated in individuals with…”
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Asymmetric dimethylarginine (ADMA) : A novel risk factor for endothelial dysfunction : Its role in hypercholesterolemia by BÖGER, R. H, BODE-BÖGER, S. M, SZUBA, A, TSAO, P. S, CHAN, J. R, TANGPHAO, O, BLASCHKE, T. F, COOKE, J. P

“…Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthase. Because endothelial NO elaboration is impaired in…”
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Phytoestrogens and cardiovascular health by Wroblewski Lissin, Lynette, Cooke, John P

“…Coronary artery disease is the leading overall cause of mortality for women and increases dramatically after menopause. Estrogen has many beneficial…”
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Gene Therapy Inhibiting Neointimal Vascular Lesion: In vivo Transfer of Endothelial Cell Nitric Oxide Synthase Gene by von der Leyen, Heiko E., Gibbons, Gary H., Morishita, Ryuichi, Lewis, Neil P., Zhang, Lunan, Nakajima, Masatoshi, Kaneda, Yasufumi, Cooke, John P., Dzau, Victor J.

“…It is postulated that vascular disease involves a disturbance in the homeostatic balance of factors regulating vascular tone and structure. Recent developments…”
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Cardiovascular Effects of Exercise: Role of Endothelial Shear Stress by Niebauer, Josef, Cooke, John P.

“…Experimental, epidemiologic and clinical studies have provided strong evidence that physical exercise has beneficial effects on multiple physiological…”
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NITRIC OXIDE SYNTHASE: Role in the Genesis of Vascular Disease by Cooke, MD, John P, Dzau, MD, Victor J

“…The product of nitric oxide (NO) synthase is the most potent endogenous vasodilator known. NO not only is a potent vasodilator, it also inhibits platelet…”
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Nitric Oxide Induces the Synthesis of Vascular Endothelial Growth Factor by Rat Vascular Smooth Muscle Cells by Dulak, Józef, Józkowicz, Alicja, Dembinska-Kiec, Aldona, Guevara, Ibeth, Zdzienicka, Anna, Zmudzinska-Grochot, Danuta, Florek, Izabela, Wójtowicz, Anna, Szuba, Andrzej, Cooke, John P

“…ABSTRACTVascular endothelial growth factor (VEGF) is known to induce the release of nitric oxide (NO) from endothelial cells. However, the effect of NO on VEGF…”
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Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit by COOKE, J. P, SINGER, A. H, TSAO, P, ZERA, P, ROWAN, R. A, BILLINGHAM, M. E

“…The purpose of this study was to determine if chronic administration of L-arginine, the precursor of endothelium-derived relaxing factor (EDRF), normalizes…”
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Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine by TSAO, P. S, MCEVOY, L. M, DREXLER, H, BUTCHER, E. C, COOKE, J. P

“…We have shown that chronic administration of the nitric oxide (NO) precursor L-arginine normalizes NO-dependent vasodilation and markedly inhibits…”
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Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactions by Hopkins, P M, Cooke, P J, Clarke, R C, Guttormsen, A B, Platt, P R, Dewachter, P, Ebo, D G, Garcez, T, Garvey, L H, Hepner, D L, Khan, D A, Kolawole, H, Kopac, P, Krøigaard, M, Laguna, J J, Marshall, S D, Mertes, P M, Rose, M A, Sabato, V, Savic, L C, Savic, S, Takazawa, T, Volcheck, G W, Voltolini, S, Sadleir, P H M

“…Grading schemes for severity of suspected allergic reactions have been applied to the perioperative setting, but there is no scoring system that estimates the…”
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Fatal herpes simplex virus hepatitis following neoadjuvant chemoradiotherapy and anterior resection for rectal cancer by Toomey, D P, Dhadda, A S, Sanni, L A, Cooke, J P, Hartley, J E

“…We describe the case of a young patient who contracted fatal herpes simplex virus hepatitis following neoadjuvant chemoradiotherapy and anterior resection for…”
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Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans by CREAGER, M. A, COOKE, J. P, MENDELSOHN, M. E, GALLAGHER, S. J, COLEMAN, S. M, LOSCALZO, J, DZAU, V. J

“…The effect of hypercholesterolemia on vascular function was studied in humans. To eliminate the potential confounding effects of atherosclerosis, vascular…”
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Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator by COOKE, J. P, ROSSITCH, E. JR, ANDON, N. A, LOSCALZO, J, DZAU, V. J

“…Flow-mediated vasodilation is endothelium dependent. We hypothesized that flow activates a potassium channel on the endothelium, and that activation of this…”
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Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes by Beisswenger, P. J., Brown, W. V., Ceriello, A., Le, N. A., Goldberg, R. B., Cooke, J. P., Robbins, D. C., Sarwat, S., Yuan, H., Jones, C. A., Tan, M. H.

“…Diabet. Med. 28, 1088–1095 (2011) Aim  To determine if a regimen with prandial + basal insulin compared with basal insulin attenuates post‐meal inflammatory…”
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Shear stress elevates endothelial cGMP : role of a potassium channel and G protein coupling by OHNO, M, GIBBONS, G. H, DZAU, V. J, COOKE, J. P

“…The endothelium acts as the sensor of shear stress and as the mediator of flow-induced changes in vessel tone and structure. The purpose of this study was to…”
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Fluid flow inhibits endothelial adhesiveness : Nitric oxide and transcriptional regulation of VCAM-1 by TSAO, P. S, BUITRAGO, R, CHAN, J. R, COOKE, J. P

“…In the arterial tree, regions exposed to reduced shear stress (low and/or disturbed flow) are predisposed to atherogenesis. Fluid flow is a potent stimulus for…”
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Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations by Savic, L C, Khan, D A, Kopac, P, Clarke, R C, Cooke, P J, Dewachter, P, Ebo, D G, Garcez, T, Garvey, L H, Guttormsen, A B, Hopkins, P M, Hepner, D L, Kolawole, H, Krøigaard, M, Laguna, J J, Marshall, S D, Mertes, P M, Platt, P R, Rose, M A, Sabato, V, Sadleir, P H M, Savic, S, Takazawa, T, Voltolini, S, Volcheck, G W

“…Unsubstantiated penicillin-allergy labels are common in surgical patients, and can lead to significant harm through avoidance of best first-line prophylaxis of…”
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History of oceanic front development in the New Zealand sector of the Southern Ocean during the Cenozoic-a synthesis by Nelson, Campbell S., Cooke, Penelope J.

“…The New Zealand sector of the Southern Ocean (NZSSO) has opened about the Indian-Pacific spreading ridge throughout the Cenozoic. Today the NZSSO is…”
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