Search Results - "COOK, WILLIAM J."

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    Crystal structure of Cryptosporidium parvum pyruvate kinase by Cook, William J, Senkovich, Olga, Aleem, Khadijah, Chattopadhyay, Debasish

    Published in PloS one (09-10-2012)
    “…Pyruvate kinase plays a critical role in cellular metabolism of glucose by serving as a major regulator of glycolysis. This tetrameric enzyme is allosterically…”
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    Structure of human desArg-C5a by Cook, William J., Galakatos, Nicholas, Boyar, William C., Walter, Richard L., Ealick, Steven E.

    “…The anaphylatoxin C5a is derived from the complement component C5 during activation of the complement cascade. It is an important component in the pathogenesis…”
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    Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling by Pawar, Pritish S, Micoli, Keith J, Ding, Haitao, Cook, William J, Kappes, John C, Chen, Yabing, McDonald, Jay M

    Published in Biochemical journal (15-06-2008)
    “…We and others have demonstrated that Fas-mediated apoptosis is a potential therapeutic target for cholangiocarcinoma. Previously, we reported that CaM…”
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    Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase by Cook, William J., Senkovich, Olga, Hernandez, Agustin, Speed, Haley, Chattopadhyay, Debasish

    “…The protozoan parasite Cryptosporidium parvum causes waterborne diseases worldwide. There is no effective therapy for C. parvum infection. The parasite depends…”
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    Bill Cook's Strategic Planning for America's Schools by Cook, William J., Jr

    Published 1988
    “…Leadership that plans strategically can initiate the changes most likely to improve public education. The first section of this book is an introduction…”
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    Brief communication : Glomerulonephritis in patients with hepatitis C cirrhosis undergoing liver transplantation by MCGUIRE, Brendan M, JULIAN, Bruce A, BYNON, J. Steve, COOK, William J, KING, Steven J, CURTIS, John J, ACCORTT, Neil A, ECKHOFF, Devin E, DIENSTAG, Jules L

    Published in Annals of internal medicine (16-05-2006)
    “…Patients infected with hepatitis C virus (HCV) frequently develop renal failure after liver transplantation. To describe renal histologic characteristics and…”
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    Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase by Pugmire, Matthew J, Cook, William J, Jasanoff, Alan, Walter, Mark R, Ealick, Steven E

    Published in Journal of molecular biology (14-08-1998)
    “…Two new crystal forms of Escherichia coli thymidine phosphorylase (EC 2.4.2.4) have been found; a monoclinic form (space group P2 1) and an orthorhombic form…”
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    Finding Real Roots of Polynomials Using Sturm Sequences by Bossé, Michael J., Cook, William J., Castonguay, Joseph M.

    “…Following a line of inquiry regarding the exact number of real roots of a real polynomial, this investigation considers: Descartes' Rule of Signs, the…”
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    Association of CD20+ Infiltrates with Poorer Clinical Outcomes in Acute Cellular Rejection of Renal Allografts by Hippen, Benjamin E., DeMattos, Angelo, Cook, William J., Kew, Clifton E., Gaston, Robert S.

    Published in American journal of transplantation (01-09-2005)
    “…We undertook a study to ascertain the relationship between the presence of CD20‐positive B‐lymphocytes in renal allografts undergoing acute cellular rejection…”
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    The correspondence of Thomas Dale (1700-1750): Botany in the transatlantic Republic of Letters by Cook, William J

    “…This paper seeks to provide a full account of the life and career of Dr. Thomas Dale (1700-1750), with particular reference to his botanical works and…”
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    An n-dimensional Pythagorean Theorem by Cook, William J.

    Published in The College mathematics journal (01-03-2013)
    “…An n-dimensional generalization of the standard cross product leads to an ndimensional generalization of the Pythagorean theorem…”
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    Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism by Senkovich, Olga, Cook, William J., Mirza, Shaper, Hollingshead, Susan K., Protasevich, Irina I., Briles, David E., Chattopadhyay, Debasish

    Published in Journal of molecular biology (20-07-2007)
    “…Human lactoferrin, a component of the innate immune system, kills a wide variety of microorganisms including the Gram positive bacteria Streptococcus…”
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    An unexpected phosphate binding site in glyceraldehyde 3-phosphate dehydrogenase: crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme by Cook, William J, Senkovich, Olga, Chattopadhyay, Debasish

    Published in BMC structural biology (25-02-2009)
    “…The structure, function and reaction mechanism of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) have been extensively studied. Based on these studies, three…”
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