Search Results - "CONZEN, P. F"

Sevoflurane preserves the endothelial glycocalyx against ischaemia–reperfusion injury by Annecke, T., Chappell, D., Chen, C., Jacob, M., Welsch, U., Sommerhoff, C.P., Rehm, M., Conzen, P.F., Becker, B.F.

“…Healthy vascular endothelium is coated by the glycocalyx, important in multiple endothelial functions, but destroyed by ischaemia–reperfusion. The impact of…”
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Effects of sevoflurane and propofol on ischaemia–reperfusion injury after thoracic-aortic occlusion in pigs by Annecke, T., Kubitz, J.C., Kahr, S., Hilberath, J.M., Langer, K., Kemming, G.I., Rehm, M., Bittmann, I., Conzen, P.F.

“…Thoraco-abdominal-aneurysm surgery predicts high mortality. Propofol and sevoflurane are commonly used anaesthetics for this procedure. Halogenated…”
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Lung injury following thoracic aortic occlusion: comparison of sevoflurane and propofol anaesthesia by ANNECKE, T., KUBITZ, J. C., LANGER, K., HILBERATH, J. M., KAHR, S., KROMBACH, F., BITTMANN, I., REHM, M., KEMMING, G. I., CONZEN, P. F.

“…Background: Halogenated anaesthetics have been shown to reduce ischaemia–reperfusion injuries in various organs due to pre‐ and post‐conditioning mechanisms…”
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Renal Function and Serum Fluoride Concentrations in Patients with Stable Renal Insufficiency After Anesthesia with Sevoflurane or Enflurane by Conzen, Peter F., Nuscheler, Manfred, Melotte, Anne, Verhaegen, Marleen, Leupolt, Thorsten, Van Aken, Hugo, Peter, Klaus

“…Sevoflurane is metabolized to hexa-fluoro-isopropanol and inorganic fluoride by the human liver. Its use as an anesthetic may lead to peak plasma fluoride…”
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Sevoflurane and isoflurane protect the reperfused guinea pig heart by reducing postischemic adhesion of polymorphonuclear neutrophils by HEINDL, B, REICHLE, F. M, ZAHLER, S, CONZEN, P. F, BECKER, B. F

“…Polymorphonuclear neutrophils (PMNs) contribute to reperfusion injury. Because volatile anesthetics can reduce PMN adhesion in the reperfused, nonworking…”
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Inhibition of neutrophil activation by volatile anesthetics decreases adhesion to cultured human endothelial cells by MÖBERT, J, ZAHIER, S, BECKER, B. F, CONZEN, P. F

“…Polymorphonuclear leukocytes (neutrophils, PMNs) have been shown to mediate vascular and tissue injury, leading to so-called systemic inflammatory response…”
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The effects of sevoflurane, halothane, enflurane, and isoflurane on hepatic blood flow and oxygenation in chronically instrumented greyhound dogs by FRINK, E. J, MORGAN, S. E, COETZEE, A, CONZEN, P. F, BROWN, B. R

“…Inhalational anesthetics produce differential effects on hepatic blood flow and oxygenation that may impact hepatocellular function and drug clearance. In this…”
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Systemic and Regional Hemodynamics of Isoflurane and Sevoflurane in Rats by Conzen, Peter F., Vollmar, Brigitte, Habazettl, Helmut, Frink, Edward J., Peter, Klaus, Messmer, Konrad

“…The authors studied the effects of sevoflurane and isoflurane on systemic hemodynamics and regional blood flow distribution (microsphere technique) in 15 rats…”
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Halothane, isoflurane, and sevoflurane reduce postischemic adhesion of neutrophils in the coronary system by KOWALSKI, C, ZAHLER, S, BECKER, B. F, FLAUCHER, A, CONZEN, P. F, GERLACH, E, PETER, K

“…Polymorphonuclear neutrophils (PMNs) contribute to postischemic reperfusion damage in many organs and tissues, a prerequisite being adhesion of PMNs to…”
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Volatile anaesthetics reduce adhesion of blood platelets under low-flow conditions in the coronary system of isolated guinea pig hearts by Heindl, B., Becker, B. F., Zahler, S., Conzen, P. F.

“…Background: Inhibitory effects of volatile anaesthetics on platelet aggregation have been demonstrated in several studies. However, the influence of volatile…”
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S(+)-ketamine, but not R(-)-ketamine, reduces postischemic adherence of neutrophils in the coronary system of isolated guinea pig hearts by SZEKELY, A, HEINDL, B, ZAHLER, S, CONZEN, P. F, BECKER, B. F

“…Polymorphonuclear neutrophils (PMN) play a crucial role in the initiation of reperfusion injury. In a previous study, we found that ketamine reduced the…”
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Heterogeneous microvascular coronary vasodilation by adenosine and nitroglycerin in dogs by Habazettl, H, Vollmar, B, Christ, M, Baier, H, Conzen, P F, Peter, K

“…We investigated the effects of adenosine and nitroglycerin (NTG) on coronary microvessel diameters (intravital fluorescence microscopy) and coronary perfusion…”
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The volatile anesthetic sevoflurane mitigates cardiodepressive effects of platelets in reperfused hearts by Heindl, B, Conzen, P F, Becker, B F

“…Adherent platelets in the coronary system can impair cardiac pump function. The volatile anesthetics sevoflurane, halothane, and isoflurane have been shown to…”
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Blood Flow and Tissue Oxygen Pressures of Liver and Pancreas in Rats: Effects of Volatile Anesthetics and of Hemorrhage by Vollmar, Brigitte, Conzen, Peter F., Kerner, Thomas, Habazettl, Helmut, Vierl, Martin, Waldner, Helmut, Peter, Klaus

“…The object of this investigation was to compare the effects of volatile anesthetics and of hemorrhage at comparable arterial blood pressures on splanchnic…”
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Coronary microcirculation during halothane, enflurane, isoflurane, and adenosine in dogs by CONZEN, P. F, HABAZETTL, H, VOLLMAR, B, CHRIST, M, BAIER, H, PETER, K

“…We investigated the effects of clinically administered volatile anesthetics and of adenosine on the microvasculature of the in situ beating canine heart…”
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Heparin reversal by protamine in humans--complement, prostaglandins, blood cells, and hemodynamics by Hobbhahn, J, Conzen, P F, Habazettl, H, Gutmann, R, Kellermann, W, Peter, K

“…Fourteen noncardiac surgical patients received heparin (10,000 IU), which was neutralized by 100 mg protamine injected within 2 min during steady-state…”
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Heparin-protamine reactions in pigs: role of oxygen-derived free radicals by Vollmar, B, Conzen, P F, Habazettl, H, Yekebas, E, Peter, K

“…We tested the hypothesis that pulmonary hypertension and thromboxane A2 release after heparin neutralization by protamine are mediated by oxygen free radicals…”
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Thromboxane mediation of pulmonary hemodynamic responses after neutralization of heparin by protamine in pigs by CONZEN, P. F, HABAZETTL, H, GUTMANN, R, HOBBHAHN, J, GOETZ, A. E, PETER, K, BRENDEL, W

“…Protamine neutralization of heparin is often associated with severe hemodynamic side-effects, including pulmonary hypertension and systemic hypotension…”
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Beneficial effect of cyclooxygenase inhibition on adverse hemodynamic responses after protamine by HOBBHAHN, J, CONZEN, P. F, ZENKER, B, GOETZ, A. E, PETER, K, BRENDEL, W

“…The hypothesis that adverse effects observed when heparin is antagonized by protamine are mediated by metabolites of the arachidonic acid cascade was tested…”
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Effect of leukopenia on pulmonary hypertension after heparin-protamine in pigs by Habazettl, H, Conzen, P F, Vollmar, B, Yekebas, E, Peter, K

“…Heparin neutralization by protamine after cardiac surgery and cardiopulmonary bypass may be associated with complement activation, transient leukopenia,…”
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