Search Results - "CONSTANTINO, Luis"

Esters of pyrazinoic acid are active against pyrazinamide-resistant strains of Mycobacterium tuberculosis and other naturally resistant mycobacteria in vitro and ex vivo within macrophages by RODRIGUES PIRES, DAVID ALEXANDRE, Valente, Emília, Simões, Marta Filipa, Carmo, Nuno, Testa, Bernard, Vicente Constantino, Luis Filipe, RIBEIRO DOS SANTOS ANES, ELSA MARIA

“…Copyright © 2015, American Society for Microbiology. All Rights Reserved. Pyrazinamide (PZA) is active against major Mycobacterium tuberculosis species (M…”
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Further Evidence of the Melatonin Calmodulin Interaction: Effect on CaMKII Activity by Argueta, Jesús, Solís-Chagoyán, Héctor, Estrada-Reyes, Rosa, Constantino-Jonapa, Luis A, Oikawa-Sala, Julián, Velázquez-Moctezuma, Javier, Benítez-King, Gloria

“…Melatonin (MEL) is a pleiotropic indolamine that reaches multiple intracellular targets. Among these, MEL binds to calmodulin (CaM) with high affinity. In…”
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A coffee berry borer (Hypothenemus hampei) genome assembly reveals a reduced chemosensory receptor gene repertoire and male-specific genome sequences by Navarro-Escalante, Lucio, Hernandez-Hernandez, Erick M., Nuñez, Jonathan, Acevedo, Flor E., Berrio, Alejandro, Constantino, Luis M., Padilla-Hurtado, Beatriz E., Molina, Diana, Gongora, Carmenza, Acuña, Ricardo, Stuart, Jeff, Benavides, Pablo

“…Coffee berry borer—CBB ( Hypothenemus hampei ) is a globally important economic pest of coffee ( Coffea spp.). Despite current insect control methods for…”
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Neuroinflammation, Microbiota-Gut-Brain Axis, and Depression: The Vicious Circle by Reyes-Martínez, Sandy, Segura-Real, Lorena, Gómez-García, Ana Pamela, Tesoro-Cruz, Emiliano, Constantino-Jonapa, Luis A, Amedei, Amedeo, Aguirre-García, María M

“…Depression is the leading cause of disability worldwide, contributing to the global disease burden. From above, it is a priority to investigate models that…”
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Antidepressant Low Doses of Ketamine and Melatonin in Combination Produce Additive Neurogenesis in Human Olfactory Neuronal Precursors by Estrada-Reyes, Rosa, Quero-Chávez, Daniel B, Alarcón-Elizalde, Salvador, Cercós, Montserrat G, Trueta, Citlali, Constantino-Jonapa, Luis A, Oikawa-Sala, Julián, Argueta, Jesús, Cruz-Garduño, Ricardo, Dubocovich, Margarita L, Benítez-King, Gloria A

“…Melatonin (MEL), an indolamine with diverse functions in the brain, has been shown to produce antidepressant-like effects, presumably through stimulating…”
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EhRab21 mobilization during erythrophagocytosis in Entamoeba histolytica by Constantino‐Jonapa, Luis A., Hernández‐Ramírez, Verónica Ivonne, Osorio‐Trujillo, Carlos, Talamás‐Rohana, Patricia

“…Rab proteins are present in all eukaryotic lineages and regulate vesicular trafficking. Entamoeba histolytica has approximately 100 genes encoding Rab…”
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Synthesis, Activity, Toxicity, and In Silico Studies of New Antimycobacterial N -Alkyl Nitrobenzamides by Pais, João P, Antoniuk, Olha, Pires, David, Delgado, Tiago, Fortuna, Andreia, Costa, Paulo J, Anes, Elsa, Constantino, Luis

“…Tuberculosis (TB) is a disease that plagues the frailest members of society. We have developed a family of -alkyl nitrobenzamides that exhibit promising…”
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Development of New Drugs to Treat Tuberculosis Based on the Dinitrobenzamide Scaffold by Delgado, Tiago, Pais, João P, Pires, David, Estrada, Filipe G A, Guedes, Rita C, Anes, Elsa, Constantino, Luis

“…Tuberculosis (TB) continues to be a major global health challenge and a leading cause of death from infectious diseases. Inspired by the results from a…”
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Contribution of Trimethylamine N-Oxide (TMAO) to Chronic Inflammatory and Degenerative Diseases by Constantino-Jonapa, Luis A, Espinoza-Palacios, Yoshua, Escalona-Montaño, Alma R, Hernández-Ruiz, Paulina, Amezcua-Guerra, Luis M, Amedei, Amedeo, Aguirre-García, María M

“…Trimethylamine N-oxide (TMAO) is a metabolite produced by the gut microbiota and has been mainly associated with an increased incidence of cardiovascular…”
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Low Doses of Ketamine and Melatonin in Combination Produce Additive Antidepressant-like Effects in Mice by Estrada-Reyes, Rosa, Quero-Chávez, Daniel B., Trueta, Citlali, Miranda, Armida, Valdés-Tovar, Marcela, Alarcón-Elizalde, Salvador, Oikawa-Sala, Julián, Argueta, Jesús, Constantino-Jonapa, Luis A., Muñoz-Estrada, Jesús, Dubocovich, Margarita L., Benítez-King, Gloria

“…Major depressive disorder is a disabling disease with the number of affected individuals increasing each year. Current antidepressant treatments take between…”
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Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis by Pais, João P, Magalhães, Marta, Antoniuk, Olha, Barbosa, Ivete, Freire, Raquel, Pires, David, Valente, Emília, Testa, Bernard, Anes, Elsa, Constantino, Luis

“…One interesting approach to fight tuberculosis is the use of prodrugs that often have shown improved biological activities over drugs with poor absorption or…”
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Nitrobenzoates and Nitrothiobenzoates with Activity against M. tuberculosis by Pais, João P, Antoniuk, Olha, Freire, Raquel, Pires, David, Valente, Emília, Anes, Elsa, Constantino, Luis

“…Esters of weak acids have shown improved antimycobacterial activity over the corresponding free acids and nitro benzoates in particular have previously shown…”
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Sustainable Strategies for the Control of Pests in Coffee Crops by Góngora, Carmenza E., Gil, Zulma Nancy, Constantino, Luis Miguel, Benavides, Pablo

“…Coffee is a worldwide commodity, and both coffee-producing and coffee-consuming countries have real concerns about environmental problems and economic growth…”
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Structural and functional characterization of the divergent Entamoeba Src using Src inhibitor-1 by Lopez-Contreras, Luilli, Hernandez-Ramirez, Veronica Ivonne, Herrera-Martinez, Mayra, Montaeo, Sarita, Constantino-Jonapa, Luis Alejandro, Chavez-Munguia, Bibiana, Talamas-Rohana, Patricia

“…The abundant number of kinases that Entamoeba histolytica possesses allows us to assume that the regulation of cellular functions by…”
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Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis by Valente, Emília, Testa, Bernard, Constantino, Luís

“…•Benzoates were used as model for prodrug hydrolysis by mycobacteria.•Hydrolysis was studied in mycobacterial homogenate, liver homogenate and plasma.•Prodrugs…”
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Participation of Ca 2+ -Calmodulin-Dependent Protein Kinase II in the Antidepressant-Like Effects of Melatonin by Miranda-Riestra, Armida, Cercós, Montserrat G, Trueta, Citlali, Oikawa-Sala, Julián, Argueta, Jesús, Constantino-Jonapa, Luis A, Cruz-Garduño, Ricardo, Benítez-King, Gloria, Estrada-Reyes, Rosa

“…Melatonin ( -acetyl-5-methoxytryptamine) is an indoleamine secreted by the pineal gland during the dark phase of the photoperiod. Its main function is the…”
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Brote de Oligonychus yothersi en cafetales de Costa Rica por la ceniza del Volcán Poás durante el año 2017 by Rojas Barrantes, Mainor, Ramírez Valerio, Daniel, Constantino Chuaire, Luis Miguel

“…La arañita roja (Oligonychus yothersi) ha sido catalogada como una plaga de poca importancia en los cafetales de Costa Rica, lo cual afecta levemente solo en…”
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EhRab21 associates with the Golgi apparatus in Entamoeba histolytica by Constantino-Jonapa, Luis A., Hernández-Ramírez, Verónica Ivonne, Osorio-Trujillo, Carlos, Talamás-Rohana, Patricia

“…Rab proteins constitute the largest group of small GTPases and act as molecular switches in a wide variety of cellular processes, including proliferation,…”
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Dengue virus induced changes in Ca2+ homeostasis in human hepatic cells that favor the viral replicative cycle by Dionicio, Cinthia L., Peña, Franshelle, Constantino-Jonapa, Luis A., Vazquez, Carlos, Yocupicio-Monroy, Martha, Rosales, Romel, Zambrano, José Luis, Ruiz, Marie Christine, del Angel, Rosa M., Ludert, Juan E.

“…•Dengue virus infection of human hepatic cells increases plasma membrane permeability to Ca2+ and reduces the amount of releasable Ca2+ from the endoplasmic…”
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Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection by Pais, João Pedro, Policarpo, Margarida, Pires, David, Francisco, Ana Paula, Madureira, Ana Margarida, Testa, Bernard, Anes, Elsa, Constantino, Luís

“…Tuberculosis (TB) is currently one of the leading causes of death due to infective agents, and the growing rate of multidrug-resistant tuberculosis (MDR TB)…”
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