Search Results - "CONSTANTINE, Gregory M"

Lessons from primary immunodeficiencies: Autoimmune regulator and autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy by Constantine, Gregory M., Lionakis, Michail S.

“…Summary The discovery of the autoimmune regulator (AIRE) protein and the delineation of its critical contributions in the establishment of central immune…”
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Recent advances in understanding inherited deficiencies in immunity to infections [version 1; peer review: 2 approved] by Constantine, Gregory M, Lionakis, Michail S

“…The immune system is central to our interactions with the world in which we live and importantly dictates our response to potential allergens, toxins, and…”
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Overlap of eosinophilic esophagitis with inborn errors of immunity and immune dysregulation by Constantine, Gregory M., Khoury, Paneez

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Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease by BOHNEN, Nicolaas I, GEDELA, Satyanarayana, KUWABARA, Hiroto, CONSTANTINE, Gregory M, MATHIS, Chester A, STUDENSKI, Stephanie A, MOORE, Robert Y

“…Olfactory dysfunction is a frequent and early feature of Parkinson's disease (PD), often preceding the motor symptoms by several years. Assessment of olfactory…”
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Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease by Bohnen, Nicolaas I., Kuwabara, Hiroto, Constantine, Gregory M., Mathis, Chester A., Moore, Robert Y.

“…Recent pharmacotherapy trials in Parkinson's disease (PD) using dopaminergic neuroimaging as outcome parameter failed to show significant relationships between…”
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Genetic susceptibility to fungal infection in children by Ochoa, Sebastian, Constantine, Gregory M., Lionakis, Michail S.

“…Fungal infections have steadily increased in incidence, emerging as a significant cause of morbidity and mortality in patients with iatrogenic…”
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Extra-nigral pathological conditions are common in Parkinson's disease with freezing of gait: An in vivo positron emission tomography study by Bohnen, Nicolaas I., Frey, Kirk A., Studenski, Stephanie, Kotagal, Vikas, Koeppe, Robert A., Constantine, Gregory M., Scott, Peter J.H., Albin, Roger L., Müller, Martijn L.T.M.

“…Cholinergic denervation has been associated with falls and slower gait speed and β‐amyloid deposition with greater severity of axial motor impairments in…”
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The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1 by Oikonomou, Vasileios, Smith, Grace, Constantine, Gregory M., Schmitt, Monica M., Ferré, Elise M.N., Alejo, Julie C., Riley, Deanna, Kumar, Dhaneshwar, Dos Santos Dias, Lucas, Pechacek, Joseph, Hadjiyannis, Yannis, Webb, Taura, Seifert, Bryce A., Ghosh, Rajarshi, Walkiewicz, Magdalena, Martin, Daniel, Besnard, Marine, Snarr, Brendan D., Deljookorani, Shiva, Lee, Chyi-chia R., DiMaggio, Tom, Barber, Princess, Rosen, Lindsey B., Cheng, Aristine, Rastegar, Andre, de Jesus, Adriana A., Stoddard, Jennifer, Kuehn, Hye Sun, Break, Timothy J., Kong, Heidi H., Castelo-Soccio, Leslie, Colton, Ben, Warner, Blake M., Kleiner, David E., Quezado, Martha M., Davis, Jeremy L., Fennelly, Kevin P., Olivier, Kenneth N., Rosenzweig, Sergio D., Suffredini, Anthony F., Anderson, Mark S., Swidergall, Marc, Guillonneau, Carole, Notarangelo, Luigi D., Goldbach-Mansky, Raphaela, Neth, Olaf, Monserrat-Garcia, Maria Teresa, Valverde-Fernandez, Justo, Lucena, Jose Manuel, Gomez-Gila, Ana Lucia, Garcia Rojas, Angela, Seppänen, Mikko R. J., Lohi, Jouko, Hero, Matti, Laakso, Saila, Klemetti, Paula, Lundberg, Vanja, Ekwall, Olov, Olbrich, Peter, Winer, Karen K., Afzali, Behdad, Moutsopoulos, Niki M., Holland, Steven M., Heller, Theo, Pittaluga, Stefania, Lionakis, Michail S.

“…In this study, interferon-γ was found to play a large role in the pathogenesis of APS-1. Results were confirmed in studies in animals and led to a trial of…”
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Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting by Wright, Benjamin L., Abonia, Juan Pablo, Abud, Edsel M., Aceves, Seema S., Ackerman, Steven J., Braskett, Melinda, Chang, Joy W., Chehade, Mirna, Constantine, Gregory M., Davis, Carla M., Dellon, Evan S., Doyle, Alfred D., Durban, Raquel, Hill, David A., Jensen, Elizabeth T., Kewalramani, Anupama, Khoury, Paneez, Klion, Amy D., Kottyan, Leah, Kuang, Fei Li, McGowan, Emily C., Ruffner, Melanie A., Spencer, Lisa A., Spergel, Jonathan M., Uchida, Amiko M., Wechsler, Joshua B., Pesek, Robert D.

“…The Consortium of Eosinophilic Gastrointestinal disease Researchers (CEGIR) and The International Gastrointestinal Eosinophil Researchers (TIGERs) organized a…”
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A deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion by Ochoa, Sebastian, Hsu, Amy P, Oler, Andrew J, Kumar, Dhaneshwar, Chauss, Daniel, van Hamburg, Jan Piet, van Laar, Gustaaf G, Oikonomou, Vasileios, Ganesan, Sundar, Ferré, Elise M N, Schmitt, Monica M, DiMaggio, Tom, Barber, Princess, Constantine, Gregory M, Rosen, Lindsey B, Auwaerter, Paul G, Gandhi, Bhumika, Miller, Jennifer L, Eisenberg, Rachel, Rubinstein, Arye, Schussler, Edith, Balliu, Erjola, Shashi, Vandana, Neth, Olaf, Olbrich, Peter, Le, Kim My, Mamia, Nanni, Laakso, Saila, Nevalainen, Pasi I, Grönholm, Juha, Seppänen, Mikko R J, Boon, Louis, Uzel, Gulbu, Franco, Luis M, Heller, Theo, Winer, Karen K, Ghosh, Rajarshi, Seifert, Bryce A, Walkiewicz, Magdalena, Notarangelo, Luigi D, Zhou, Qing, Askentijevich, Ivona, Gahl, William, Dalgard, Cliffton L, Perera, Lalith, Afzali, Behdad, Tas, Sander W, Holland, Steven M, Lionakis, Michail S

“…Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a life-threatening monogenic autoimmune disorder primarily caused by biallelic…”
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Selective hyposmia in Parkinson disease: Association with hippocampal dopamine activity by Bohnen, Nicolaas I., Gedela, Satyanarayana, Herath, Priyantha, Constantine, Gregory M., Moore, Robert Y.

“…Olfactory dysfunction is common in patients with Parkinson disease (PD) and has been attributed to early pathological deposition of Lewy bodies and Lewy…”
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Twelve-year follow-up of omalizumab therapy for anaphylaxis in 2 patients with systemic mastocytosis by Constantine, Gregory M., Bressler, Peter B., Petroni, Daniel, Metcalfe, Dean D., Carter, Melody C.

“…Mast cells are constitutively activated, which account for mast cell mediator symptoms that range from mild to severe. [...]it has been reported that patients…”
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Dupilumab Use in Patients With Hypereosinophilic Syndromes: A Multicenter Case Series and Review of the Literature by Ezekwe, Ejiofor A.D., Weskamp, Andrew L., Rahim, Rodaba, Makiya, Michelle A., Wetzler, Lauren, Ware, JeanAnne M., Nelson, Celeste, Castillo, Perla Adames, Riley, Charles A., Brown, Thomas, Penrod, Lori, Constantine, Gregory M., Khoury, Paneez, Boggs, Nathan A., Klion, Amy D.

“…Hypereosinophilic syndromes (HES) are defined as hypereosinophilia with eosinophil-related clinical manifestations, some of which overlap in presentation with…”
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Gastrointestinal segmental remission with oral budesonide therapy for eosinophilic gastrointestinal diseases by Khalid, Mian B., Sharma, Disha, Howard, Amari, Akbulut, Dilara, Sampaio de Melo, Michelly, Quezado, Martha M., Castillo, Perla A., Cuevas, Gustavo A., Klion, Amy D., Khoury, Paneez, Constantine, Gregory M., Kumar, Sheila

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Remission of indolent systemic mastocytosis in the absence of targeted therapy by Constantine, Gregory M., Metcalfe, Dean D., Akin, Cem, Sun, Xiaoping, Bai, Yun, Eisch, A. Robin, Maric, Irina, Komarow, Hirsh D.

“…SM is currently classified into one of several variants: indolent SM (ISM), smoldering SM, SM with associated hematological neoplasm, aggressive SM, and mast…”
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Regional cerebral cholinergic nerve terminal integrity and cardinal motor features in Parkinson’s disease by Bohnen, Nicolaas I, Kanel, Prabesh, Koeppe, Robert A, Sanchez-Catasus, Carlos A, Frey, Kirk A, Scott, Peter, Constantine, Gregory M, Albin, Roger L, Müller, Martijn L T M

“…Abstract Clinical effects of anti-cholinergic drugs implicate cholinergic systems alterations in the pathophysiology of some cardinal motor impairments in…”
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Platelet-derived growth factor receptor-alpha-positive myeloid neoplasm presenting as eosinophilic gastrointestinal disease by Constantine, Gregory M., Ware, JeanAnne, Brown, Thomas, Thumm, Lauren, Kamal, Natasha, Kumar, Sheila, Kleiner, David, Maric, Irina, Klion, Amy D.

“…The GI tract is the third most common organ system involved at initial presentation,2 and predominate GI involvement as the presenting symptom in HESs has been…”
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Cognitive correlates of cortical cholinergic denervation in Parkinson's disease and parkinsonian dementia by BOHNEN, Nicolaas I, KAUFER, Daniel I, HENDRICKSON, Rick, IVANCO, Larry S, LOPRESTI, Brian J, CONSTANTINE, Gregory M, MATHIS, Chester A, DAVIS, James G, MOORE, Robert Y, DEKOSKY, Steven T

“…We recently reported findings that loss of cortical acetylcholinesterase (AChE) activity is greater in parkinsonian dementia than in Alzheimer's disease (AD)…”
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DETERMINANTAL GENERATING FUNCTIONS OF COLORED SPANNING FORESTS by Constantine, Gregory M., Buliga, Marius G.

“…The color type of a spanning forest of a graph with colored edges is defined and, subsequently, it is proved that the generating function of such spanning…”
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Age-associated striatal dopaminergic denervation and falls in community-dwelling subjects by Bohnen, Nicolaas I, Muller, Martijn L T M, Kuwabara, Hiroto, Cham, Rakié, Constantine, Gregory M, Studenski, Stephanie A

“…Older adults have a high prevalence of gait and balance disturbances and falls. Normal aging is associated with significant striatal dopaminergic denervation,…”
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