Search Results - "CONNOR, Joseph P"

Anti-SARS-CoV-2 IgG and IgA antibodies in COVID-19 convalescent plasma do not enhance viral infection by Clark, Natasha M, Janaka, Sanath Kumar, Hartman, William, Stramer, Susan, Goodhue, Erin, Weiss, John, Evans, David T, Connor, Joseph P

“…The novel coronavirus, SARS-CoV-2 that causes COVID-19 has resulted in the death of nearly 4 million people within the last 18 months. While preventive…”
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Pre-operative anemia and peri-operative transfusion are associated with poor oncologic outcomes in cancers of the esophagus: potential impact of patient blood management on cancer outcomes by Connor, Joseph P, Destrampe, Eric, Robbins, Daniel, Hess, Aaron S, McCarthy, Daniel, Maloney, James

“…Both Red Blood Cell (RBC) transfusion and anemia are thought to negatively impact cancer survival. These effects have been reported with mixed findings in…”
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Predicting the efficacy of COVID-19 convalescent plasma donor units with the Lumit Dx anti-receptor binding domain assay by Janaka, Sanath Kumar, Clark, Natasha M, Evans, David T, Mou, Huihui, Farzan, Michael, Connor, Joseph P

“…Background The novel coronavirus SARS-CoV2 that causes COVID-19 has resulted in the death of more than 2.5 million people, but no cure exists. Although passive…”
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Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers by PYEON, Dohun, NEWTON, Michael A, KELSEY, Karl T, TUREK, Lubomir P, AHLQUIST, Paul, LAMBERT, Paul F, DEN BOON, Johan A, SENGUPTA, Srikumar, MARSIT, Carmen J, WOODWORTH, Craig D, CONNOR, Joseph P, HAUGEN, Thomas H, SMITH, Elaine M

“…Human papillomaviruses (HPV) are associated with nearly all cervical cancers, 20% to 30% of head and neck cancers (HNC), and other cancers. Because HNCs also…”
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MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells by Gubbels, Jennifer A A, Felder, Mildred, Horibata, Sachi, Belisle, Jennifer A, Kapur, Arvinder, Holden, Helen, Petrie, Sarah, Migneault, Martine, Rancourt, Claudine, Connor, Joseph P, Patankar, Manish S

“…Cancer cells utilize a variety of mechanisms to evade immune detection and attack. Effective immune detection largely relies on the formation of an immune…”
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Unusual Cardiac Presentation of COVID-19 and Use of Convalescent Plasma by Hartman, William R., Connor, Joseph P., Hess, Aaron S.

“…COVID-19 infection caused by the SARS-CoV-2 virus has been associated with cardiac abnormalities, including conduction abnormalities. Convalescent plasma is…”
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DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1 by Connor, Joseph P, Felder, Mildred, Kapur, Arvinder, Onujiogu, Nonyem

“…Overcoming platinum resistance is a major obstacle in the treatment of Epithelial Ovarian Cancer (EOC). In our previous work Decoy Receptor 3 (DcR3) was found…”
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Hospitalized COVID-19 patients treated with convalescent plasma in a mid-size city in the Midwest by Hartman, William R, Hess, Aaron S, Connor, Joseph P

“…SARS-CoV-2 and its associated disease, COVID-19, has infected over seven million people world-wide, including two million people in the United States. While…”
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The detection, treatment, and biology of epithelial ovarian cancer by Gubbels, Jennifer Aa, Claussen, Nick, Kapur, Arvinder K, Connor, Joseph P, Patankar, Manish S

“…Ovarian cancer is particularly insidious in nature. Its ability to go undetected until late stages coupled with its non-descript signs and symptoms make it the…”
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Persistent viral RNA shedding after COVID‐19 symptom resolution in older convalescent plasma donors by Hartman, William R., Hess, Aaron S., Connor, Joseph P.

“…Introduction The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is responsible for a worldwide pandemic. While the medical…”
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Peri-operative allogeneic blood transfusion is associated with poor overall survival in advanced epithelial ovarian Cancer; potential impact of patient blood management on Cancer outcomes by Connor, Joseph P., O'Shea, Andrea, McCool, Kevin, Sampene, Emmanuel, Barroilhet, Lisa M.

“…Transfusion related immune modulation associated with red blood cell (RBC) transfusion is thought to result in decreased cancer survival. Results in epithelial…”
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HN125: A Novel Immunoadhesin Targeting MUC16 with Potential for Cancer Therapy by Xiang, Xinran, Feng, Mingqian, Felder, Mildred, Connor, Joseph P, Man, Yan-Gao, Patankar, Manish S, Ho, Mitchell

“…The mucin MUC16 expresses the repeating peptide epitope CA125 that has been known for decades to be a well-validated cancer marker that is overexpressed on the…”
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Outcomes of red blood cell transfusions prescribed in organ donors by the Digital Intern, an electronic decision support algorithm by Connor, Joseph P., Raife, Thomas, Medow, Joshua E.

“…BACKGROUND The Digital Intern (DI) is an electronic decision support tool for the management of organ donors. One algorithm determines the dose, in units of…”
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Defining postoperative transfusion thresholds in liver transplant recipients: A novel retrospective approach by Connor, Joseph P., Aufhauser, David, Welch, Bridget M., Leverson, Glen, Al‐Adra, David

“…Background The optimal transfusion threshold for most patient populations has been defined as hematocrit (HCT) <21%. However, some specific patient populations…”
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Blood products and liver transplantation: A strategy to balance optimal preparation with effective blood stewardship by Little, Christopher J., Leverson, Glen E., Hammel, Laura L., Connor, Joseph P., Al‐Adra, David P.

“…Background Unanticipated transfusion requirements during liver transplantation can delay lifesaving intraoperative resuscitation and strain blood bank…”
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Electronic clinical decision support to facilitate a change in clinical practice: Small details can make or break success by Connor, Joseph P., Medow, Joshua E., Ehlenfeldt, Bradley D., Rose, Anne E., Raife, Thomas

“…Background The use of electronic clinical decision support (CDS) is becoming common to change historically common clinical practices considered outdated by…”
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AKR1B10 expression by immunohistochemistry in surgical resections and fine needle aspiration cytology material in patients with cystic pancreatic lesions; potential for improved nonoperative diagnosis by Connor, Joseph P., Esbona, Karla, Matkowskyj, Kristina A.

“…Cystic pancreatic tumors account for 10% of cystic lesions in the pancreas. Evaluation focuses on identifying lesions that require surgical resection due to…”
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Sonohysterography and endometrial cancer: incidence and functional viability of disseminated malignant cells by Berry, Emily, MD, Lindheim, Steven R., MD, Connor, Joseph P., MD, Hartenbach, Ellen M., MD, Schink, Julian C., MD, Harter, Josephine, MD, Eickhoff, Jens C., PhD, Kushner, David M., MD

“…Objective The purpose of this study was to evaluate sonohysterography in patients with endometrial cancer and to determine whether (1) transtubal fluid spill…”
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The blood utilization calculator, a target‐based electronic decision support algorithm, increases the use of single‐unit transfusions in a large academic medical center by Connor, Joseph P., Raife, Thomas, Medow, Joshua E., Ehlenfeldt, Bradley D., Sipsma, Kristen

“…BACKGROUND Electronic decision support has been used to reduce use of red blood cell (RBC) transfusion. With the goal of reducing transfusions, we modified our…”
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Ascites from epithelial ovarian cancer contain high levels of functional decoy receptor 3 (DcR3) and is associated with platinum resistance by Connor, Joseph P, Felder, Mildred

“…Abstract Objective Decoy receptor 3 (DcR3), a soluble tumor necrosis factor receptor is a known binding partner of multiple apoptotic ligands inhibiting…”
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