Search Results - "CONNELLY, M"

The Emerging Role of RNA as a Therapeutic Target for Small Molecules by Connelly, Colleen M, Moon, Michelle H, Schneekloth, Jr, John S

“…Recent advances in understanding different RNAs and unique features of their biology have revealed a wealth of information. However, approaches to identify…”
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Predictors of recurrence of Crohn’s disease after ileocolectomy: A review by Connelly, Tara M, Messaris, Evangelos

“…Recurrence after ileocolectomy for Crohn’s disease(CD) is common and occurs in up to 80% of patients. Such recurrence can result in repeated surgical…”
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Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma by Young, Douglas D, Connelly, Colleen M, Grohmann, Christoph, Deiters, Alexander

“…MicroRNAs are a recently discovered new class of important endogenous regulators of gene function. Aberrant regulation of microRNAs has been linked to various…”
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Experimental investigation of the sound absorption characteristics of vegetated roofs by Connelly, M., Hodgson, M.

“…An experimental investigation of the sound absorption characteristics of vegetated roof substrates and plots has been completed. First, an impedance tube was…”
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Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity by Crunelli, Vincenzo, Lőrincz, Magor L., Connelly, William M., David, François, Hughes, Stuart W., Lambert, Régis C., Leresche, Nathalie, Errington, Adam C.

“…During low-vigilance states, thalamic neurons exhibit diverse rhythmic activities that contribute to specific parts of the electroencephalogram rhythm. In this…”
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Small Molecule Inhibition of MicroRNA miR-21 Rescues Chemosensitivity of Renal-Cell Carcinoma to Topotecan by Naro, Yuta, Ankenbruck, Nicholas, Thomas, Meryl, Tivon, Yaniv, Connelly, Colleen M, Gardner, Laura, Deiters, Alexander

“…Chemical probes of microRNA (miRNA) function are potential tools for understanding miRNA biology that also provide new approaches for discovering therapeutics…”
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Nurses' Descriptions of Interdisciplinary Interactions in Stroke and Geriatric Rehabilitation Units: A Case Example of the Registered Practical Nurse by Masood, Mehvish, Guitar, Nicole A, Connelly, Denise M, Nguyen, Angela

“…To analyse how nurses describe their interactions with other interdisciplinary team members within stroke and geriatric rehabilitation. A secondary analysis of…”
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Frameshifting at collided ribosomes is modulated by elongation factor eEF3 and by integrated stress response regulators Gcn1 and Gcn20 by Houston, Lisa, Platten, Evan M, Connelly, Sara M, Wang, Jiyu, Grayhack, Elizabeth J

“…Ribosome stalls can result in ribosome collisions that elicit quality control responses, one function of which is to prevent ribosome frameshifting, an…”
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An analysis of the cost and impact of cosmetic tourism and its associated complications: A multi institutional study by Rafeh, Saeed, Tara M., Connelly, Michael, Flanagan, Amy, Gillis, Elaf, Osman, Paul, Ridgway, James, O’Riordan, Aidan, Manning, Seamus, Murphy, Gerrard, O’Donoghue

“…The increasing cost of cosmetic procedures, long elective waiting times in the public system and affordability of procedures offered abroad has driven the…”
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Neuromuscular contributions to the age-related reduction in muscle power: Mechanisms and potential role of high velocity power training by McKinnon, Neal B, Connelly, Denise M, Rice, Charles L, Hunter, Susan W, Doherty, Timothy J

“…Highlights • Neuromuscular adaptations with age result in reduced muscle contraction velocity. • This leads to an accelerated loss of muscle power compared to…”
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Autaptic connections and synaptic depression constrain and promote gamma oscillations by Connelly, William M

“…Computational models of gamma oscillations have helped increase our understanding of the mechanisms that shape these 40-80 Hz cortical rhythms. Evidence…”
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Bridging Educational Grant in Nursing (BEGIN) students’ intentions for retention in long-term, home and community care: A survey protocol by Connelly, Denise M, Hay, Melissa Erin, Guitar, Nicole Ann, Prentice, Kristin

“…IntroductionRetention of nurses in long-term care (LTC) and home and community care (HCC) settings is a growing concern. Previous evidence underscores factors…”
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Graduate Student Literature Review: Serotonin and calcium metabolism: A story unfolding by Connelly, M K, Cheng, A A, Hernandez, L L

“…The peripartum period is characterized by dynamic shifts in metabolic, mineral, and immune metabolism as the dairy cow adapts to the demands of lactation…”
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Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression by Parmar, Shaifaly, Bume, Desta Doro, Connelly, Colleen M., Boer, Robert E., Prestwood, Peri R., Wang, Zhen, Labuhn, Henning, Sinnadurai, Krishshanthi, Feri, Adeline, Ouellet, Jimmy, Homan, Philip, Numata, Tomoyuki, Schneekloth, John S.

“…Riboswitches are structured RNA elements that regulate gene expression upon binding to small molecule ligands. Understanding the mechanisms by which small…”
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‘Getting back to real living’: a qualitative study of the process of community reintegration after stroke by Wood, Jennifer P, Connelly, Denise M, Maly, Monica R

“…Objectives: To examine the process of community reintegration over the first year following stroke, from the patient’s perspective. Design: Qualitative,…”
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Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity by Ellingson, Benjamin M., Malkin, Mark G., Rand, Scott D., Connelly, Jennifer M., Quinsey, Carolyn, LaViolette, Pete S., Bedekar, Devyani P., Schmainda, Kathleen M.

“…Purpose: To present comprehensive examinations of the assumptions made in functional diffusion map (fDM) analyses and provide a biological basis for fDM…”
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Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays by Connelly, Colleen M, Boer, Robert E, Moon, Michelle H, Gareiss, Peter, Schneekloth, John S

“…The identification of small molecules that bind to and perturb the function of microRNAs is an attractive approach for the treatment for microRNA-associated…”
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Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays by Connelly, Colleen M, Abulwerdi, Fardokht A, Schneekloth, Jr, John S

“…New methods to identify RNA-binding small molecules open yet unexplored opportunities for the pharmacological modulation of RNA-driven biology and disease…”
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Photodynamic therapy (PDT) for malignant brain tumors – Where do we stand? by Quirk, Brendan J, Brandal, Garth, Donlon, Steven, Vera, Juan Carlos, Mang, Thomas S, Foy, Andrew B, Lew, Sean M, Girotti, Albert W, Jogal, Sachin, LaViolette, Peter S, Connelly, Jennifer M, Whelan, Harry T

“…Highlights • A measurable degree of necrosis to a depth of about 5 mm, with efficacy to about 1 cm not unreasonable. • Cavitary PDT with HpD results are…”
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Resilience for working in Ontario home and community care: registered practical nurses need the support of themselves, family and clients, and employers by Connelly, Denise M, Garnett, Anna, Prentice, Kristin, Hay, Melissa E, Guitar, Nicole A, Snobelen, Nancy, Smith-Carrier, Tracy, McKay, Sandra M, King, Emily C, Calver, Jen, Sinha, Samir

“…The context of practice is often not explicit in the discourse around the personal and professional resilience of nurses. The unique factors related to…”
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