Search Results - "CONLEY, EDWARD C."

Resting and Activation-Dependent Ion Channels in Human Mast Cells by Duffy, S. Mark, Lawley, Wendy J, Conley, Edward C, Bradding, Peter

“…The mechanism of mediator secretion from mast cells in disease is likely to include modulation of ion channel activity. Several distinct Ca(2+), K(+), and…”
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Bridging two translation gaps: A new informatics research agenda for telemonitoring of chronic disease by Hardisty, Alex R, Peirce, Susan C, Preece, Alun, Bolton, Charlotte E, Conley, Edward C, Gray, W. Alex, Rana, Omer F, Yousef, Zaheer, Elwyn, Glyn

“…Highlights ► We propose a research agenda for evolving telemonitoring systems for chronic disease. ► The focus is on detecting deterioration early enough to…”
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Multigene family isoform profiling from blood cell lineages by Dewson, Grant, Conley, Edward C, Bradding, Peter

“…Analysis of cell-selective gene expression for families of proteins of therapeutic interest is crucial when deducing the influence of genes upon complex traits…”
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Detecting deterioration in patients with chronic disease using telemonitoring: navigating the 'trough of disillusionment' by Elwyn, Glyn, Hardisty, Alex R., Peirce, Susan C., May, Carl, Evans, Robert, Robinson, Douglas K. R., Bolton, Charlotte E., Yousef, Zaheer, Conley, Edward C., Rana, Omer F., Gray, W. Alex, Preece, Alun D.

“…Objectives  To examine the evidence base for telemonitoring designed for patients who have chronic obstructive pulmonary disease and heart failure, and to…”
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Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release by Thompson, G J, Langlais, C, Cain, K, Conley, E C, Cohen, G M

“…Efflux of intracellular K(+) and cell shrinkage are features of apoptosis in many experimental systems, and a regulatory role has been proposed for cytoplasmic…”
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Simultaneous trend analysis for evaluating outcomes in patient-centred health monitoring services by Conley, Edward C., Owens, David R., Luzio, Stephen L., Subramanian, Mahesh, Ali, Ali Shaikh, Hardisty, Alex, Rana, Omer

“…The research aim underpinning the Healthcare@Home (HH) information system described here was to enable ‘near real time’ risk analysis for disease early…”
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Alchemist multimodal workflows for diabetic retinopathy research, disease prevention and investigational drug discovery by Riposan, Adina, Taylor, Ian, Owens, David R, Rana, Omer, Conley, Edward C

“…In this paper we present mechanisms for imaging and spectral data discovery, as applied to the early detection of pathologic mechanisms underlying diabetic…”
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Internet information on ion channels: issues of access and organization by Conley, E C

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The TRIACS analytical workflows platform for distributed clinical decision support by Riposan, A., Taylor, I.J., Rana, O., Owens, D.R., Conley, E.C.

“…In this paper we discuss a flexible distributed workflow-based approach that enables researchers to study biomedical data for creating decision support…”
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Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release by THOMPSON, Gwilym J., LANGLAIS, Claudia, CAIN, Kelvin, CONLEY, Edward C., COHEN, Gerald M.

“…Efflux of intracellular K+ and cell shrinkage are features of apoptosis in many experimental systems, and a regulatory role has been proposed for cytoplasmic…”
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Characterisation of Kir2.0 proteins in the rat cerebellum and hippocampus by polyclonal antibodies by Stonehouse, A H, Pringle, J H, Norman, R I, Stanfield, P R, Conley, E C, Brammar, W J

“…Rabbit polyclonal antibodies were raised to rat Kir2.0 (Kir2.1, Kir2.2 and Kir2.3) inwardly rectifying potassium ion channel proteins. The antibody…”
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Co-localization of the Inwardly Rectifying Potassium Ion Channel, Kir2.2, and the Substance P Receptor in Single Locus Coeruleus Neurons by STONEHOUSE, ANTHONY H., PRINGLE, J. HOWARD, NORMAN, ROBERT I., STANFIELD, PETER R., CONLEY, EDWARD C., BRAMMAR, WILLIAM J.

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Improving Disease Early Detection and Prevention by Multiplex Longitudinal Outcomes Marker Modeling by Conley, E.C., Owens, D.R.

“…We are interested in understanding how high quality information management systems can improve disease prevention and screening services, particularly in the…”
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Homologous pairing and the formation of nascent synaptic intermediates between regions of duplex DNA by RecA protein by Conley, E C, West, S C

“…The RecA protein from E. coli gains access to duplex DNA, by nucleation from a short single-stranded gap, to form a spiral nucleoprotein filament that is…”
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Underwinding of DNA associated with duplex-duplex pairing by RecA protein by CONLEY, E. C, WEST, S. C

“…Homologous pairing between gapped circular and partially homologous form I DNA, catalyzed by Escherichia coli RecA protein, leads to the formation of nascent…”
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Distribution of cGMP-gated cation channel expression in bovine and porcine cardiovascular tissue by Ratcliffe, C F, Conley, E C, Brammar, W J

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An isoform of the cGMP-gated retinal photoreceptor channel gene expressed in the sinoatrial node (pacemaker) region of rabbit heart by Hundal, S P, DiFrancesco, D, Mangoni, M, Brammar, W J, Conley, E C

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Healthcare@Home: Research Models for Patient-Centred Healthcare Services by Subramanian, M., Ali, A.S., Rana, O., Hardisty, A., Conley, E.C.

“…Healthcare@Home is a research project implementing a prototype to `push' or `pull' data via mobile devices and/or dedicated home-based network servers to one…”
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Cloning and characterization of a cDNA encoding a human brain potassium channel by Freeman, S N, Conley, E C, Brennand, J C, Russell, N J, Brammar, W J

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Mechanism and genetic control of recombination in bacteria by Conley, E C

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