Search Results - "CONLEY, E. C"

Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors by MULRYAN, K, GITTERMAN, D. P, EVANS, R. J, LEWIS, C. J, VLAI, C, LECKIE, B. J, COBB, A. L, BROWN, J. E, CONLEY, E. C, BUELL, G, PRITCHARD, C. A

“…P2X1 receptors for ATP are ligand-gated cation channels, present on many excitable cells including vas deferens smooth muscle cells. A substantial component of…”
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Voltage-dependent and calcium-activated ion channels in the human mast cell line HMC-1 by Duffy, S. M., Leyland, M. L., Conley, E. C., Bradding, P.

“…The mechanisms underlying the recruitment, differentiation, and sustained activation of mast cells in disease are likely to include modulation of ion channels…”
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Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release by Thompson, G J, Langlais, C, Cain, K, Conley, E C, Cohen, G M

“…Efflux of intracellular K(+) and cell shrinkage are features of apoptosis in many experimental systems, and a regulatory role has been proposed for cytoplasmic…”
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Human mast cell ion channels by Bradding, P., Conley, E. C.

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A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1 by Stanfield, P R, Davies, N W, Shelton, P A, Sutcliffe, M J, Khan, I A, Brammar, W J, Conley, E C

“…1. We describe the effects on channel function of changing an aspartate residue (Asp172) in a membrane-spanning alpha-helix of the murine inward rectifier,…”
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Resting and Activation-Dependent Ion Channels in Human Mast Cells by Duffy, S. Mark, Lawley, Wendy J, Conley, Edward C, Bradding, Peter

“…The mechanism of mediator secretion from mast cells in disease is likely to include modulation of ion channel activity. Several distinct Ca(2+), K(+), and…”
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The intrinsic gating of inward rectifier K+ channels expressed from the murine IRK1 gene depends on voltage, K+ and Mg2 by Stanfield, P R, Davies, N W, Shelton, P A, Khan, I A, Brammar, W J, Standen, N B, Conley, E C

“…1. We describe the cloning of the inward rectifier K+ channel IRK1 from genomic DNA of mouse; the gene is intronless. 2. The IRK1 gene can be stably expressed…”
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The dependence of Ag+ block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter by Dart, C., Leyland, M. L., Barrett‐Jolley, R., Shelton, P. A., Spencer, P. J., Conley, E. C., Sutcliffe, M. J., Stanfield, P. R.

“…Externally applied Ag + (100-200 n m ) irreversibly blocked the strong inwardly rectifying K + channel, Kir2.1. Mutation to serine of a cysteine residue at…”
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Characterisation of Kir2.0 proteins in the rat cerebellum and hippocampus by polyclonal antibodies by Stonehouse, A H, Pringle, J H, Norman, R I, Stanfield, P R, Conley, E C, Brammar, W J

“…Rabbit polyclonal antibodies were raised to rat Kir2.0 (Kir2.1, Kir2.2 and Kir2.3) inwardly rectifying potassium ion channel proteins. The antibody…”
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Underwinding of DNA associated with duplex-duplex pairing by RecA protein by CONLEY, E. C, WEST, S. C

“…Homologous pairing between gapped circular and partially homologous form I DNA, catalyzed by Escherichia coli RecA protein, leads to the formation of nascent…”
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Homologous pairing and the formation of nascent synaptic intermediates between regions of duplex DNA by RecA protein by Conley, E C, West, S C

“…The RecA protein from E. coli gains access to duplex DNA, by nucleation from a short single-stranded gap, to form a spiral nucleoprotein filament that is…”
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Mechanism of intramolecular recyclization and deletion formation following transformation of Escherichia coli with linearized plasmid DNA by CONLEY, E. C, SAUNDERS, V. A, JACKSON, V, SAUNDERS, J. R

“…The deletion end-points of a number of type I (less than monomeric) plasmid deletants obtained by transforming recA+ or recA- E. coli with linear pBR322 DNA…”
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Recombination-dependent recircularization of linearized pBR322 plasmid DNA following transformation of Escherichia coli by Conley, E C, Saunders, J R

“…Monomeric pBR322 DNA that had been linearized at its unique SalI site transformed wild-type Escherichia coli with 10(2) to 10(3) times less efficiency than CCC…”
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Effect of Preoperative Sport Participation on Post-Operative Outcomes in Patients Undergoing Knee Cartilage Surgery by Conley, C E Whale, Howard, J S, Jacobs, C A, Lattermann, C, Mattacola, C G

“…An abstract of a study by Whale Conley et al evaluating if preoperative sport level affects post-operative outcomes is presented. Although both sporting and…”
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Factor Analysis of the KOOS Does Not Indicate the Existence of 5 Unique Subscales by Howard, J S, Conley, C E Whale, Jacobs, C A, Lattermann, C

“…An abstract of a study by Howard et al determining the number of latent factors evaluated by the Knee Injury and Osteoarthritis Outcome Score (KOOS) is…”
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Regulated expression of K+ channel genes in electrically silent mammalian cells by linkage to beta-globin gene-activation elements by Shelton, P A, Davies, N W, Antoniou, M, Grosveld, F, Needham, M, Hollis, M, Brammar, W J, Conley, E C

“…Fundamental studies of the mechanism of human beta-like globin gene-expression have identified DNA sequences (locus control regions or LCRs) which directly…”
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An isoform of the cGMP-gated retinal photoreceptor channel gene expressed in the sinoatrial node (pacemaker) region of rabbit heart by Hundal, S P, DiFrancesco, D, Mangoni, M, Brammar, W J, Conley, E C

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Co-localization of the Inwardly Rectifying Potassium Ion Channel, Kir2.2, and the Substance P Receptor in Single Locus Coeruleus Neurons by STONEHOUSE, ANTHONY H., PRINGLE, J. HOWARD, NORMAN, ROBERT I., STANFIELD, PETER R., CONLEY, EDWARD C., BRAMMAR, WILLIAM J.

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Deafness after ethacrynic acid by Ng, P S, Conley, C E, Ing, T S

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Distribution of cGMP-gated cation channel expression in bovine and porcine cardiovascular tissue by Ratcliffe, C F, Conley, E C, Brammar, W J

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