Search Results - "COMINI, Mara"

Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series by RIVARA, Mirko, ZULIANI, Valentina, BERTONI, Simona, PLAZZI, Pier Vincenzo, COCCONCELLI, Giuseppe, MORINI, Giovanni, COMINI, Mara, RIVARA, Silvia, MOR, Marco, BORDI, Fabrizio, BAROCELLI, Elisabetta, BALLABENI, Vigilio

“…A novel series of non-imidazole H(3)-receptor antagonists was developed, by chemical modification of a potent lead H(3)-antagonist composed by an imidazole…”
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Benzisothiazoles and $\beta$-Adrenoceptors: Synthesis and Pharmacological lnvestigation of Novel Propanolamine and Oxypro-panolamine Derivatives in Isolated Rat Tissues by Morini Giovanni, Poli Enzo, Comini Mara, Menozzi Alessandro, Pozzoli Cristina

“…In an attempt to examine the ability of benzisothiazole-based drugs to interact with $\beta$-adrenoceptors, a series of 1,2-benzisothiazole derivatives, which…”
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Dual‐Acting Drugs: an in vitro Study of Nonimidazole Histamine H 3 Receptor Antagonists Combining Anticholinesterase Activity by Incerti, Matteo, Flammini, Lisa, Saccani, Francesca, Morini, Giovanni, Comini, Mara, Coruzzi, Massimo, Barocelli, Elisabetta, Ballabeni, Vigilio, Bertoni, Simona

“…Dual‐acting compounds that combine H 3 antagonism with anticholinesterase properties are currently emerging as a novel and promising therapeutic approach in…”
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Synthesis and structure–activity relationships for biphenyl H 3 receptor antagonists with moderate anti-cholinesterase activity by Morini, Giovanni, Comini, Mara, Rivara, Mirko, Rivara, Silvia, Bordi, Fabrizio, Plazzi, Pier Vincenzo, Flammini, Lisa, Saccani, Francesca, Bertoni, Simona, Ballabeni, Vigilio, Barocelli, Elisabetta, Mor, Marco

“…A series of H 3-antagonists with a 4,4′-biphenyl scaffold was developed, in which the terminal groups were modulated, providing compounds with high H 3…”
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Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity by MORINI, Giovanni, COMINI, Mara, BAROCELLI, Elisabetta, MOR, Marco, RIVARA, Mirko, RIVARA, Silvia, BORDI, Fabrizio, VINCENZO PLAZZI, Pier, FLAMMINI, Lisa, SACCANI, Francesca, BERTONI, Simona, BALLABENI, Vigilio

“…The combination of antagonism at histamine H(3) receptors and inhibition of acetylcholinesterase has been recently proposed as an approach to devise putative…”
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In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity by Bertoni, Simona, Ballabeni, Vigilio, Flammini, Lisa, Saccani, Francesca, Domenichini, Giuseppe, Morini, Giovanni, Comini, Mara, Rivara, Mirko, Barocelli, Elisabetta

“…The pharmacological profiling of potent histamine H 3 -ligands initiated in a previous study is completed here. In vitro functional and binding studies…”
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Dibasic non-imidazole histamine H3 receptor antagonists with a rigid biphenyl scaffold by MORINI, Giovanni, COMINI, Mara, BAROCELLI, Elisabetta, PLAZZI, Pier Vincenzo, RIVARA, Mirko, RIVARA, Silvia, LORENZI, Simone, BORDI, Fabrizio, MOR, Marco, FLAMMINI, Lisa, BERTONI, Simona, BALLABENI, Vigilio

“…A class of rigid, dibasic, non-imidazole H3 antagonists was developed, starting from a series of previously described flexible compounds. The original…”
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Dibasic non-imidazole histamine H 3 receptor antagonists with a rigid biphenyl scaffold by Morini, Giovanni, Comini, Mara, Rivara, Mirko, Rivara, Silvia, Lorenzi, Simone, Bordi, Fabrizio, Mor, Marco, Flammini, Lisa, Bertoni, Simona, Ballabeni, Vigilio, Barocelli, Elisabetta, Plazzi, Pier Vincenzo

“…A class of rigid dibasic H 3 antagonists is reported. Compound 5 with subnanomolar affinity for human H 3 receptor was identified. A class of rigid, dibasic,…”
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Dual-Acting Drugs: an in vitro Study of Nonimidazole Histamine H3 Receptor Antagonists Combining Anticholinesterase Activity by Incerti, Matteo, Flammini, Lisa, Saccani, Francesca, Morini, Giovanni, Comini, Mara, Coruzzi, Massimo, Barocelli, Elisabetta, Ballabeni, Vigilio, Bertoni, Simona

“…Dual‐acting compounds that combine H3 antagonism with anticholinesterase properties are currently emerging as a novel and promising therapeutic approach in the…”
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In vitro pharmacology at human histamine H 3 receptors and brain access of non-imidazole alkylpiperidine derivatives by Bertoni, Simona, Flammini, Lisa, Manenti, Veronica, Ballabeni, Vigilio, Morini, Giovanni, Comini, Mara, Barocelli, Elisabetta

“…In this report, we describe the pharmacological profile of alkylpiperidine derivatives at human histamine H 3 receptors and their ability to access central…”
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Discovery of histamine H3 receptor antagonistic property of simple imidazole-free derivatives: Preliminary pharmacological investigation by Barocelli, Elisabetta, Ballabeni, Vigilio, Manenti, Veronica, Flammini, Lisa, Bertoni, Simona, Morini, Giovanni, Comini, Mara, Impicciatore, Mariannina

“…The histamine H3 receptor subtype negatively modulates the release of various neurotransmitters such as histamine, glutamate, norepinephrine, acetylcholine and…”
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Synthesis and biological evaluation of new non-imidazole H 3-receptor antagonists of the 2-aminobenzimidazole series by Rivara, Mirko, Zuliani, Valentina, Cocconcelli, Giuseppe, Morini, Giovanni, Comini, Mara, Rivara, Silvia, Mor, Marco, Bordi, Fabrizio, Barocelli, Elisabetta, Ballabeni, Vigilio, Bertoni, Simona, Plazzi, Pier Vincenzo

“…The synthesis and biological evaluation of a new class of non-imidazole H 3-receptor antagonists, characterized by a 2-aminobenzimidazole fragment connected to…”
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Stereospecific effects of benzo[d]isothiazolyloxypropanolamine derivatives at β-adrenoceptors: Synthesis, chiral resolution, and biological activity in vitro by Comini, Mara, Pozzoli, Cristina, Incerti, Matteo, Rossi, Daniela, Collina, Simona, Azzolina, Ornella, Di Vittorio, Elena, Morini, Giovanni, Poli, Enzo

“…We performed the asymmetric synthesis of four enantiopure benzo[d] isothiazo‐3‐or 5‐yloxypropanolamine derivatives, previously described as competitive…”
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Synthesis and structure-activity relationships for biphenyl H sub(3 receptor antagonists with moderate anti-cholinesterase activity) by Morini, Giovanni, Comini, Mara, Rivara, Mirko, Rivara, Silvia, Bordi, Fabrizio, Plazzi, Pier Vincenzo, Flammini, Lisa, Saccani, Francesca, Bertoni, Simona, Ballabeni, Vigilio, Barocelli, Elisabetta, Mor, Marco

“…The combination of antagonism at histamine H sub(3 receptors and inhibition of acetylcholinesterase has been recently proposed as an approach to devise…”
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In vitro pharmacology at human histamine H3 receptors and brain access of non-imidazole alkylpiperidine derivatives by Bertoni, Simona, Flammini, Lisa, Manenti, Veronica, Ballabeni, Vigilio, Morini, Giovanni, Comini, Mara, Barocelli, Elisabetta

“…In this report, we describe the pharmacological profile of alkylpiperidine derivatives at human histamine H(3) receptors and their ability to access central…”
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Benzisothiazoles and β-adrenoceptors: Synthesis and pharmacological investigation of novel propanolamine and oxypro-panolamine derivatives in isolated rat tissues by Morini, Giovanni, Poli, Enzo, Comini, Mara, Menozzi, Alessandro, Pozzoli, Cristina

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Benzisothiazoles and beta-adrenoceptors: synthesis and pharmacological investigation of novel propanolamine and oxypropanolamine derivatives in isolated rat tissues by Morini, Giovanni, Poli, Enzo, Comini, Mara, Menozzi, Alessandro, Pozzoli, Cristina

“…In an attempt to examine the ability of benzisothiazole-based drugs to interact with beta-adrenoceptors, a series of 1,2-benzisothiazole derivatives, which…”
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Discovery of histamine H 3 receptor antagonistic property of simple imidazole-free derivatives: Preliminary pharmacological investigation by Barocelli, Elisabetta, Ballabeni, Vigilio, Manenti, Veronica, Flammini, Lisa, Bertoni, Simona, Morini, Giovanni, Comini, Mara, Impicciatore, Mariannina

“…The histamine H 3 receptor subtype negatively modulates the release of various neurotransmitters such as histamine, glutamate, norepinephrine, acetylcholine…”
Get full text

Synthesis and biological evaluation of new non-imidazole H sub(3)-receptor antagonists of the 2-aminobenzimidazole series by Rivara, Mirko, Zuliani, Valentina, Cocconcelli, Giuseppe, Morini, Giovanni, Comini, Mara, Rivara, Silvia, Mor, Marco, Bordi, Fabrizio, Barocelli, Elisabetta, Ballabeni, Vigilio, Bertoni, Simona, Plazzi, Pier Vincenzo

“…A novel series of non-imidazole H sub(3)-receptor antagonists was developed, by chemical modification of a potent lead H sub(3)-antagonist composed by an…”
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Dibasic non-imidazole histamine H sub(3) receptor antagonists with a rigid biphenyl scaffold by Morini, Giovanni, Comini, Mara, Rivara, Mirko, Rivara, Silvia, Lorenzi, Simone, Bordi, Fabrizio, Mor, Marco, Flammini, Lisa, Bertoni, Simona, Ballabeni, Vigilio, Barocelli, Elisabetta, Plazzi, Pier Vincenzo

“…A class of rigid, dibasic, non-imidazole H sub(3) antagonists was developed, starting from a series of previously described flexible compounds. The original…”
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