Search Results - "COMELY, Oliver A"
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Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial
Published in The Lancet infectious diseases (01-04-2012)“…Summary Background Infection with Clostridium difficile is the primary infective cause of antibiotic-associated diarrhoea. We aimed to compare efficacy and…”
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Habitual daily intake of a sweet and fatty snack modulates reward processing in humans
Published in Cell metabolism (04-04-2023)“…Western diets rich in fat and sugar promote excess calorie intake and weight gain; however, the underlying mechanisms are unclear. Despite a well-documented…”
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Treatment of First Recurrence of Clostridium difficile Infection: Fidaxomicin Versus Vancomycin
Published in Clinical infectious diseases (01-08-2012)“…Recurrence of Clostridium difficile infection (CDI) occurs in approximately 25% of successfully treated patients. Two phase 3 randomized, double-blind trials…”
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COVID-19 Associated Pulmonary Aspergillosis (CAPA)—From immunology to treatment
Published in Journal of fungi (Basel) (24-06-2020)“…Like severe influenza, coronavirus disease-19 (COVID-19) resulting in acute respiratory distress syndrome (ARDS) has emerged as an important disease that…”
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Phase 1b study of new posaconazole tablet for prevention of invasive fungal infections in high-risk patients with neutropenia
Published in Antimicrobial agents and chemotherapy (01-10-2014)“…Posaconazole tablets, a new oral formulation of posaconazole, can be effective when given as antifungal prophylaxis to neutropenic patients at high risk for…”
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Monkeypox in children and adult women in Europe: Results from a flash VACCELERATE pilot survey
Published in Enfermedades infecciosas y microbiología clínica (01-05-2023)Get full text
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Pilot Study of Extracorporeal Removal of Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia
Published in Circulation (New York, N.Y.) (23-08-2011)“…Targeted therapies to stabilize the clinical manifestations and prolong pregnancy in preeclampsia do not exist. Soluble fms-like tyrosine kinase 1 (sFlt-1), an…”
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Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia
Published in The New England journal of medicine (25-01-2007)“…In this randomized trial of patients undergoing treatment for acute myelogenous leukemia or the myelodysplastic syndrome, prophylaxis with posaconazole…”
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Improved outcome in central nervous system aspergillosis, using voriconazole treatment
Published in Blood (15-10-2005)“…The mortality of central nervous system (CNS) aspergillosis approaches 100%, requiring improved therapies. Voriconazole gives superior efficacy and survival in…”
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All You Need To Know and More about the Diagnosis and Management of Rare Yeast Infections
Published in mBio (31-08-2021)“…Invasive infections with emerging yeasts such as , , and other species are associated with high morbidity and mortality rates. Due to the rarity and…”
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Patients at High Risk of Invasive Fungal Infections: When and How to Treat
Published in Drugs (New York, N.Y.) (01-01-2008)“…When and how to treat invasive fungal infections (IFIs) is discussed in this review, with a focus on the two most prevalent non-endemic IFIs, namely invasive…”
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Caspofungin versus Liposomal Amphotericin B for Empirical Antifungal Therapy in Patients with Persistent Fever and Neutropenia
Published in The New England journal of medicine (30-09-2004)“…This multinational, double-blind trial compared caspofungin, an echinocandin, with liposomal amphotericin B as empirical antifungal therapy in 1095 patients…”
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Contemporary Strategies in the Prevention and Management of Fungal Infections
Published in Infectious disease clinics of North America (01-03-2016)“…Major patient groups at risk for invasive fungal infection are found in hematology, intensive care, and abdominal surgery units. The vast majority of invasive…”
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Pharmacokinetics of Oral Posaconazole in Neutropenic Patients Receiving Chemotherapy for Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Published in Pharmacotherapy (01-10-2008)“…Study Objective. To analyze the pharmacokinetics of posaconazole administered as prophylaxis for invasive fungal infection (IFI) in neutropenic patients…”
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Evidence-based assessment of primary antifungal prophylaxis in patients with hematologic malignancies
Published in Blood (01-05-2003)“…Invasive fungal infection is an increasing source of morbidity and mortality in patients with hematologic malignancies, particularly those with prolonged and…”
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Microbiological Characterization and Clinical Outcomes After Extended-Pulsed Fidaxomicin Treatment for Clostridioides difficile Infection in the EXTEND Study
Published in Open forum infectious diseases (01-11-2019)“…( ) infection (CDI) is diagnosed using clinical signs and symptoms plus positive laboratory tests. Recurrence of CDI after treatment is common, and coinfection…”
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Numbers Needed to Treat with Posaconazole Prophylaxis to Prevent Invasive Fungal Infection and Death
Published in Clinical infectious diseases (15-05-2008)Get full text
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