Search Results - "COMANDUCCI, Maurizio"

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines by Donnelly, John, Medini, Duccio, Boccadifuoco, Giuseppe, Biolchi, Alessia, Ward, Joel, Frasch, Carl, Moxon, E. Richard, Stella, Maria, Comanducci, Maurizio, Bambini, Stefania, Muzzi, Alessandro, Andrews, William, Chen, Jie, Santos, George, Santini, Laura, Boucher, Philip, Serruto, Davide, Pizza, Mariagrazia, Rappuoli, Rino, Giuliani, Marzia Monica

“…A uniquemulticomponent vaccine against serogroup B meningococci incorporates the novel genome-derived proteins fHbp, NHBA, and NadA that may vary in sequence…”
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Predicted Strain Coverage of a New Meningococcal Multicomponent Vaccine (4CMenB) in Spain: Analysis of the Differences with Other European Countries by Abad, Raquel, Medina, Verónica, Stella, Maria, Boccadifuoco, Giuseppe, Comanducci, Maurizio, Bambini, Stefania, Muzzi, Alessandro, Vázquez, Julio A

“…A novel meningococcal multicomponent vaccine, 4CMenB (Bexsero®), has been approved in Europe, Canada, Australia and US. The potential impact of 4CMenB on…”
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Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination by Budroni, Sonia, Siena, Emilio, Hotopp, Julie C. Dunning, Seib, Kate L., Serruto, Davide, Nofroni, Chiara, Comanducci, Maurizio, Riley, David R., Daugherty, Sean C., Angiuoli, Samuel V., Covacci, Antonello, Pizza, Mariagrazia, Rappuoli, Rino, Moxon, E. Richard, Tettelin, Hervé, Medini, Duccio

“…Molecular data on a limited number of chromosomal loci have shown that the population of Neisseria meningitidis (Nm), a deadly human pathogen, is structured in…”
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A Universal Vaccine for Serogroup B Meningococcus by Giuliani, Marzia M., Adu-Bobie, Jeannette, Comanducci, Maurizio, Aricò, Beatrice, Savino, Silvana, Santini, Laura, Brunelli, Brunella, Bambini, Stefania, Biolchi, Alessia, Capecchi, Barbara, Cartocci, Elena, Ciucchi, Laura, Di Marcello, Federica, Ferlicca, Francesca, Galli, Barbara, Luzzi, Enrico, Masignani, Vega, Serruto, Davide, Veggi, Daniele, Contorni, Mario, Morandi, Maurizio, Bartalesi, Alessandro, Cinotti, Vanda, Mannucci, Donatella, Titta, Francesca, Ovidi, Elisa, Welsch, Jo Anne, Granoff, Dan, Rappuoli, Rino, Pizza, Mariagrazia

“…Meningitis and sepsis caused by serogroup B meningococcus are two severe diseases that still cause significant mortality. To date there is no universal vaccine…”
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An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands by Bambini, Stefania, Piet, Jurgen, Muzzi, Alessandro, Keijzers, Wendy, Comandi, Sara, De Tora, Lisa, Pizza, Mariagrazia, Rappuoli, Rino, van de Beek, Diederik, van der Ende, Arie, Comanducci, Maurizio

“…Studies of meningococcal evolution and genetic population structure, including the long-term stability of non-random associations between variants of surface…”
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Characterization of fHbp, nhba (gna2132), nadA, porA, and Sequence Type in Group B Meningococcal Case Isolates Collected in England and Wales during January 2008 and Potential Coverage of an Investigational Group B Meningococcal Vaccine by Lucidarme, Jay, Comanducci, Maurizio, Findlow, Jamie, Gray, Stephen J, Kaczmarski, Edward B, Guiver, Malcolm, Vallely, Pamela J, Oster, Philipp, Pizza, Mariagrazia, Bambini, Stefania, Muzzi, Alessandro, Borrow, Ray

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Fine Antigenic Specificity and Cooperative Bactericidal Activity of Monoclonal Antibodies Directed at the Meningococcal Vaccine Candidate Factor H-Binding Protein by Beernink, Peter T, Welsch, Jo Anne, Bar-Lev, Michal, Koeberling, Oliver, Comanducci, Maurizio, Granoff, Dan M

“…No broadly protective vaccine is available for the prevention of group B meningococcal disease. One promising candidate is factor H-binding protein (fHbp),…”
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Characterization of Diverse Subvariants of the Meningococcal Factor H (fH) Binding Protein for Their Ability To Bind fH, To Mediate Serum Resistance, and To Induce Bactericidal Antibodies by Seib, Kate L, Brunelli, Brunella, Brogioni, Barbara, Palumbo, Emmanuelle, Bambini, Stefania, Muzzi, Alessandro, DiMarcello, Federica, Marchi, Sara, van der Ende, Arie, Aricó, Beatrice, Savino, Silvana, Scarselli, Maria, Comanducci, Maurizio, Rappuoli, Rino, Giuliani, Marzia M, Pizza, Mariagrazia

“…Neisseria meningitidis is a commensal of the human nasopharynx but is also a major cause of septicemia and meningitis. The meningococcal factor H binding…”
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Characterization of fHbp, nhba (gna2132), nadA, porA, Sequence Type (ST), and Genomic Presence of IS1301 in Group B Meningococcal ST269 Clonal Complex Isolates from England and Wales by Lucidarme, Jay, Comanducci, Maurizio, Findlow, Jamie, Gray, Stephen J, Kaczmarski, Edward B, Guiver, Malcolm, Kugelberg, Elisabeth, Vallely, Pamela J, Oster, Philipp, Pizza, Mariagrazia, Bambini, Stefania, Muzzi, Alessandro, Tang, Christoph M, Borrow, Ray

“…Highly effective glycoconjugate vaccines exist against four of the five major pathogenic groups of meningococci: A, C, W-135, and Y. An equivalent vaccine…”
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NadA, a novel vaccine candidate of Neisseria meningitidis by Comanducci, Maurizio, Bambini, Stefania, Brunelli, Brunella, Adu-Bobie, Jeannette, Aricò, Beatrice, Capecchi, Barbara, Giuliani, Marzia Monica, Masignani, Vega, Santini, Laura, Savino, Silvana, Granoff, Dan M, Caugant, Dominique A, Pizza, Mariagrazia, Rappuoli, Rino, Mora, Marirosa

“…Neisseria meningitidis is a human pathogen, which, in spite of antibiotic therapy, is still a major cause of mortality due to sepsis and meningitis. Here we…”
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NadA Diversity and Carriage in Neisseria meningitidis by COMANDUCCI, Maurizio, BAMBINI, Stefania, CAUGANT, Dominique A, MORA, Marirosa, BRUNELLI, Brunella, CAPECCHI, Barbara, CIUCCHI, Laura, RAPPUOLI, Rino, PIZZA, Mariagrazia

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Region Comprising Amino Acids 100 to 255 of Neisseria meningitidis Lipoprotein GNA 1870 Elicits Bactericidal Antibodies by Giuliani, Marzia Monica, Santini, Laura, Brunelli, Brunella, Biolchi, Alessia, Aricò, Beatrice, Di Marcello, Federica, Cartocci, Elena, Comanducci, Maurizio, Masignani, Vega, Lozzi, Luisa, Savino, Silvana, Scarselli, Maria, Rappuoli, Rino, Pizza, Mariagrazia

“…GNA 1870 is a novel surface-exposed lipoprotein, identified by genome analysis of Neisseria meningitidis strain MC58, which induces bactericidal antibodies…”
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Mu-Like Prophage in Serogroup B Neisseria meningitidis Coding for Surface-Exposed Antigens by MASIGNANI, Vega, GIULIANI, Marzia Monica, TETTELIN, Hervé, COMANDUCCI, Maurizio, RAPPUOLI, Rino, SCARLATO, Vincenzo

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen by Seib, Kate L, Scarselli, Maria, Comanducci, Maurizio, Toneatto, Daniela, Masignani, Vega

“…Neisseria meningitidis is a leading cause of meningitis and sepsis worldwide. The first broad-spectrum multicomponent vaccine against serogroup B meningococcus…”
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Could the multicomponent meningococcal serogroup B vaccine (4CMenB) control Neisseria meningitidis capsular group X outbreaks in Africa? by Hong, Eva, Giuliani, Marzia Monica, Deghmane, Ala-Eddine, Comanducci, Maurizio, Brunelli, Brunella, Dull, Peter, Pizza, Mariagrazia, Taha, Muhamed-Kheir

“…Highlights ► A new recombinant vaccine against meningococci group B is under registration. ► We examined coverage of group X isolates emerging in Africa (no…”
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Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus by Bambini, Stefania, Muzzi, Alessandro, Olcen, Per, Rappuoli, Rino, Pizza, Mariagrazia, Comanducci, Maurizio

“…Abstract With the aim of studying the molecular diversity of the antigens of a new recombinant vaccine against meningococcus serogroup B, the three genes…”
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Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide by Muzzi, Alessandro, Brozzi, Alessandro, Serino, Laura, Bodini, Margherita, Abad, Raquel, Caugant, Dominique, Comanducci, Maurizio, Lemos, Ana Paula, Gorla, Maria Cecilia, Křížová, Pavla, Mikula, Claudia, Mulhall, Robert, Nissen, Michael, Nohynek, Hanna, Simões, Maria João, Skoczyńska, Anna, Stefanelli, Paola, Taha, Muhamed-Kheir, Toropainen, Maija, Tzanakaki, Georgina, Vadivelu-Pechai, Kumaran, Watson, Philip, Vazquez, Julio A., Rajam, Gowrisankar, Rappuoli, Rino, Borrow, Ray, Medini, Duccio

“…The Meningococcal Antigen Typing System (MATS) was developed to identify meningococcus group B strains with a high likelihood of being covered by the 4CMenB…”
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Multicomponent meningococcal serogroup B vaccination elicits cross-reactive immunity in infants against genetically diverse serogroup C, W and Y invasive disease isolates by Biolchi, Alessia, De Angelis, Gabriella, Moschioni, Monica, Tomei, Sara, Brunelli, Brunella, Giuliani, Maria, Bambini, Stefania, Borrow, Ray, Claus, Heike, Gorla, Maria Cecilia O., Hong, Eva, Lemos, Ana Paula S., Lucidarme, Jay, Taha, Muhamed-Kheir, Vogel, Ulrich, Comanducci, Maurizio, Budroni, Sonia, Giuliani, Marzia M., Rappuoli, Rino, Pizza, Mariagrazia, Boucher, Philip

“…•4CMenB antigens are present and conserved in non-MenB meningococcal strains.•The antigens vary across strains in their presence, sequence relatedness and…”
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Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment by Vogel, Ulrich, Prof, Taha, Muhamed-Kheir, MD, Vazquez, Julio A, PhD, Findlow, Jamie, PhD, Claus, Heike, PhD, Stefanelli, Paola, PhD, Caugant, Dominique A, Prof, Kriz, Paula, MD, Abad, Raquel, PhD, Bambini, Stefania, PhD, Carannante, Anna, BS, Deghmane, Ala Eddine, PhD, Fazio, Cecilia, BS, Frosch, Matthias, Prof, Frosi, Giacomo, MSc, Gilchrist, Stefanie, MSc, Giuliani, Marzia M, MSc, Hong, Eva, BSc, Ledroit, Morgan, BSc, Lovaglio, Pietro G, PhD, Lucidarme, Jay, PhD, Musilek, Martin, PhD, Muzzi, Alessandro, MSc, Oksnes, Jan, MSc, Rigat, Fabio, PhD, Orlandi, Luca, PhD, Stella, Maria, PhD, Thompson, Danielle, BSc, Pizza, Mariagrazia, PhD, Rappuoli, Rino, PhD, Serruto, Davide, PhD, Comanducci, Maurizio, MSc, Boccadifuoco, Giuseppe, MSc, Donnelly, John J, PhD, Medini, Duccio, PhD, Borrow, Ray, Prof

“…Summary Background A novel multicomponent vaccine against meningococcal capsular group B (MenB) disease contains four major components: factor-H-binding…”
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Rational design of a meningococcal antigen inducing broad protective immunity by Scarselli, Maria, Aricò, Beatrice, Brunelli, Brunella, Savino, Silvana, Di Marcello, Federica, Palumbo, Emmanuelle, Veggi, Daniele, Ciucchi, Laura, Cartocci, Elena, Bottomley, Matthew James, Malito, Enrico, Lo Surdo, Paola, Comanducci, Maurizio, Giuliani, Marzia Monica, Cantini, Francesca, Dragonetti, Sara, Colaprico, Annalisa, Doro, Francesco, Giannetti, Patrizia, Pallaoro, Michele, Brogioni, Barbara, Tontini, Marta, Hilleringmann, Markus, Nardi-Dei, Vincenzo, Banci, Lucia, Pizza, Mariagrazia, Rappuoli, Rino

“…The sequence variability of protective antigens is a major challenge to the development of vaccines. For Neisseria meningitidis, the bacterial pathogen that…”
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