Search Results - "COLUCCI, Francesco"

The role of KIR and HLA interactions in pregnancy complications by Colucci, Francesco

“…Combinations of KIR and HLA genes associate with pregnancy complications as well as with many other clinical scenarios. Understanding how certain KIR and HLA…”
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Uterine NK cells: active regulators at the maternal-fetal interface by Moffett, Ashley, Colucci, Francesco

“…Pregnancy presents an immunological conundrum because two genetically different individuals coexist. The maternal lymphocytes at the uterine maternal-fetal…”
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Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction by Moffett, Ashley, Colucci, Francesco

“…Summary Allogeneic individuals co‐exist during pregnancy in eutherian mammals. Maternal and fetal cells intermingle at the site of placental attachment in the…”
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Sharing Knowledge With Young and Established Students of Immunology by the Neapolitan Gulf at the Ruggero Ceppellini Advanced School by Colucci, Francesco

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Uterine Natural Killer Cells: Functional Distinctions and Influence on Pregnancy in Humans and Mice by Gaynor, Louise M, Colucci, Francesco

“…Our understanding of development and function of natural killer (NK) cells has progressed significantly in recent years. However, exactly how uterine NK (uNK)…”
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A New Look at Immunogenetics of Pregnancy: Maternal Major Histocompatibility Complex Class I Educates Uterine Natural Killer Cells by Bos, Manon, Colucci, Francesco

“…Our incomplete knowledge of maternal-fetal interface (MFI) physiology impedes a better understanding of the pathological mechanisms leading to pregnancy…”
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Maternal allo-recognition of the fetus by Moffett, Ashley, M.D, Chazara, Olympe, Ph.D, Colucci, Francesco, Ph.D

“…Immunological adjustments are needed to accommodate the close contact between two genetically different individuals, the mother and her baby, during mammalian…”
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Decidualisation and placentation defects are a major cause of age-related reproductive decline by Woods, Laura, Perez-Garcia, Vicente, Kieckbusch, Jens, Wang, Xiaoqiu, DeMayo, Francesco, Colucci, Francesco, Hemberger, Myriam

“…Mammalian reproductive performance declines rapidly with advanced maternal age. This effect is largely attributed to the exponential increase in chromosome…”
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How Do Uterine Natural Killer and Innate Lymphoid Cells Contribute to Successful Pregnancy? by Huhn, Oisín, Zhao, Xiaohui, Esposito, Laura, Moffett, Ashley, Colucci, Francesco, Sharkey, Andrew M

“…Innate lymphoid cells (ILCs) are the most abundant immune cells in the uterine mucosa both before and during pregnancy. Circumstantial evidence suggests they…”
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Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention by Moffett, Ashley, Chazara, Olympe, Colucci, Francesco, Johnson, Martin H

“…Abstract A distinctive type of (uterine) natural killer (NK) cell is present in the uterine decidua during the period of placental formation. Uterine NK cells…”
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Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy by Huhn, Oisín, Ivarsson, Martin A., Gardner, Lucy, Hollinshead, Mike, Stinchcombe, Jane C, Chen, Puran, Shreeve, Norman, Chazara, Olympe, Farrell, Lydia E., Theorell, Jakob, Ghadially, Hormas, Parham, Peter, Griffiths, Gillian, Horowitz, Amir, Moffett, Ashley, Sharkey, Andrew M., Colucci, Francesco

“…During early pregnancy, decidual innate lymphoid cells (dILCs) interact with surrounding maternal cells and invading fetal extravillous trophoblasts (EVT)…”
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Molecular definition of group 1 innate lymphoid cells in the mouse uterus by Filipovic, Iva, Chiossone, Laura, Vacca, Paola, Hamilton, Russell S., Ingegnere, Tiziano, Doisne, Jean-Marc, Hawkes, Delia A., Mingari, Maria Cristina, Sharkey, Andrew M., Moretta, Lorenzo, Colucci, Francesco

“…Determining the function of uterine lymphocytes is challenging because of the dynamic changes in response to sex hormones and, during pregnancy, to the…”
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Composition, Development, and Function of Uterine Innate Lymphoid Cells by Doisne, Jean-Marc, Balmas, Elisa, Boulenouar, Selma, Gaynor, Louise M, Kieckbusch, Jens, Gardner, Lucy, Hawkes, Delia A, Barbara, Cynthia F, Sharkey, Andrew M, Brady, Hugh J M, Brosens, Jan J, Moffett, Ashley, Colucci, Francesco

“…Innate lymphoid cells (ILCs), including NK cells, contribute to barrier immunity and tissue homeostasis. In addition to the role of uterine NK cells in…”
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Immature NK cells, capable of producing IL-22, are present in human uterine mucosa by Male, Victoria, Hughes, Tiffany, McClory, Susan, Colucci, Francesco, Caligiuri, Michael A, Moffett, Ashley

“…NK cells are the dominant population of immune cells in the endometrium in the secretory phase of the menstrual cycle and in the decidua in early pregnancy…”
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KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia by Nakimuli, Annettee, Chazara, Olympe, Hiby, Susan E, Farrell, Lydia, Tukwasibwe, Stephen, Jayaraman, Jyothi, Traherne, James A, Trowsdale, John, Colucci, Francesco, Lougee, Emma, Vaughan, Robert W, Elliott, Alison M, Byamugisha, Josaphat, Kaleebu, Pontiano, Mirembe, Florence, Nemat-Gorgani, Neda, Parham, Peter, Norman, Paul J, Moffett, Ashley

“…In sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births compared with <10 deaths per 100,000 births in Europeans…”
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Designing Multifunctional Devices for Regenerative Pharmacology Based on 3D Scaffolds, Drug-Loaded Nanoparticles, and Thermosensitive Hydrogels: A Proof-of-Concept Study by Colucci, Francesco, Mancini, Vanessa, Mattu, Clara, Boffito, Monica

“…Regenerative pharmacology combines tissue engineering/regenerative medicine (TERM) with drug delivery with the aim to improve the outcomes of traditional TERM…”
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Strengthening Purity: Moral Purity as a Mediator of Direct and Extended Cross-Group Friendships on Sexual Prejudice by Vezzali, Loris, Brambilla, Marco, Giovannini, Dino, Paolo Colucci, Francesco

“…The present research investigated whether enhanced perceptions of moral purity drive the effects of intergroup cross-group friendships on the intentions to…”
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Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth by Madeja, Zofia, Yadi, Hakim, Apps, Richard, Boulenouar, Selma, Roper, Stephen J, Gardner, Lucy, Moffett, Ashley, Colucci, Francesco, Hemberger, Myriam

“…The mammalian fetus represents a semiallograft within the maternal uterus yet is not rejected. This situation is particularly pronounced in species with a…”
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Unique Receptor Repertoire in Mouse Uterine NK cells by Yadi, Hakim, Burke, Shannon, Madeja, Zofia, Hemberger, Myriam, Moffett, Ashley, Colucci, Francesco

“…Uterine NK (uNK) cells are a prominent feature of the uterine mucosa and regulate placentation. NK cell activity is regulated by a balance of activating and…”
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NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo by Lakshmikanth, Tadepally, Burke, Shannon, Ali, Talib Hassan, Kimpfler, Silvia, Ursini, Francesco, Ruggeri, Loredana, Capanni, Marusca, Umansky, Viktor, Paschen, Annette, Sucker, Antje, Pende, Daniela, Groh, Veronika, Biassoni, Roberto, Höglund, Petter, Kato, Masashi, Shibuya, Kazuko, Schadendorf, Dirk, Anichini, Andrea, Ferrone, Soldano, Velardi, Andrea, Kärre, Klas, Shibuya, Akira, Carbone, Ennio, Colucci, Francesco

“…NK cells use a variety of receptors to detect abnormal cells, including tumors and their metastases. However, in the case of melanoma, it remains to be…”
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