Search Results - "COLOMBO, Irma"

The Critical Impact of Sphingolipid Metabolism in Breast Cancer Progression and Drug Response by Corsetto, Paola Antonia, Zava, Stefania, Rizzo, Angela Maria, Colombo, Irma

“…Breast cancer is the second leading cause of cancer-related death in women in the world, and its management includes a combination of surgery, radiation…”
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HaCaT Cells as a Reliable In Vitro Differentiation Model to Dissect the Inflammatory/Repair Response of Human Keratinocytes by Corsetto, Paola Antonia, Calvieri, Stefano, Gismondi, Angela, Taramelli, Donatella, Dell'Agli, Mario, Carlino, Claudia, Fumagalli, Marco, Corbett, Yolanda, Zava, Stefania, Mattozzi, Carlo, Maggio, Roberta, Sangiovanni, Enrico, Colombo, Irma, Scaccabarozzi, Diletta

“…Cultured primary human keratinocytes are frequently employed for studies of immunological and inflammatory responses; however, interpretation of experimental…”
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ω-3 Long Chain Polyunsaturated Fatty Acids as Sensitizing Agents and Multidrug Resistance Revertants in Cancer Therapy by Corsetto, Paola Antonia, Colombo, Irma, Kopecka, Joanna, Rizzo, Angela Maria, Riganti, Chiara

“…Chemotherapy efficacy is strictly limited by the resistance of cancer cells. The ω-3 long chain polyunsaturated fatty acids (ω-3 LCPUFAs) are considered…”
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Characterization of Antioxidant Potential of Seaweed Extracts for Enrichment of Convenience Food by Corsetto, Paola Antonia, Montorfano, Gigliola, Zava, Stefania, Colombo, Irma, Ingadottir, Bergros, Jonsdottir, Rosa, Sveinsdottir, Kolbrun, Rizzo, Angela Maria

“…In recent years, there has been a growing interest in natural antioxidants as replacements of synthetic compounds because of increased safety concerns and…”
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Exogenous Fatty Acids Modulate ER Lipid Composition and Metabolism in Breast Cancer Cells by Rizzo, Angela Maria, Colombo, Irma, Montorfano, Gigliola, Zava, Stefania, Corsetto, Paola Antonia

“…(1) Background: Lipid metabolism is a fundamental hallmark of all tumors, especially of breast cancer. Few studies describe the different lipid metabolisms and…”
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Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a by Resaz, Roberta, Cangelosi, Davide, Morini, Martina, Segalerba, Daniela, Mastracci, Luca, Grillo, Federica, Bosco, Maria Carla, Bottino, Cristina, Colombo, Irma, Eva, Alessandra

“…Most patients affected by glycogen storage disease type 1a (GSD1a), an inherited metabolic disorder caused by mutations in the enzyme glucose-6-phosphatase-α…”
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Purification and In Vitro Evaluation of an Anti-HER2 Affibody-Monomethyl Auristatin E Conjugate in HER2-Positive Cancer Cells by Damiani, Isabella, Castiglioni, Silvia, Sochaj-Gregorczyk, Alicja, Bonacina, Fabrizia, Colombo, Irma, Rusconi, Valentina, Otlewski, Jacek, Corsini, Alberto, Bellosta, Stefano

“…A promising approach for the development of high-affinity tumor targeting ADCs is the use of engineered protein drugs, such as affibody molecules, which…”
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Interplay between Plasmodium falciparum haemozoin and L-arginine: implication for nitric oxide production by Corbett, Yolanda, D'Alessandro, Sarah, Parapini, Silvia, Scaccabarozzi, Diletta, Kalantari, Parisa, Zava, Stefania, Giavarini, Flavio, Caruso, Donatella, Colombo, Irma, Egan, Timothy J, Basilico, Nicoletta

“…Plasmodium falciparum haemozoin, a detoxification product of digested haemoglobin from infected erythrocytes, is released into the bloodstream upon schizont…”
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Two active and differently N-glycosylated isoforms of human ST3Gal-V are produced from the placental mRNA variant by a leaky scanning mechanism by Zava, Stefania, Milani, Simona, Sottocornola, Elena, Berra, Bruno, Colombo, Irma

“…Previously, we identified a human ST3Gal-V mRNA variant peculiarly characterized by the presence of a translational start codon localized up-stream and…”
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A Proteomic Analysis of GSD-1a in Mouse Livers: Evidence for Metabolic Reprogramming, Inflammation, and Macrophage Polarization by Cangelosi, Davide, Resaz, Roberta, Petretto, Andrea, Segalerba, Daniela, Ognibene, Marzia, Raggi, Federica, Mastracci, Luca, Grillo, Federica, Bosco, Maria Carla, Varesio, Luigi, Sica, Antonio, Colombo, Irma, Eva, Alessandra

“…Glycogen storage disease type 1a (GSD-1a) is a rare genetic disease caused by mutations in the catalytic subunit of the enzyme glucose-6-phosphatase-alpha…”
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Effects of two-months balanced diet in metabolically healthy obesity: lipid correlations with gender and BMI-related differences by Rondanelli, Mariangela, Klersy, Chaterine, Perna, Simone, Faliva, Milena Anna, Montorfano, Gigliola, Roderi, Paola, Colombo, Irma, Corsetto, Paola Antonia, Fioravanti, Marisa, Solerte, Sebastiano Bruno, Rizzo, Angela Maria

“…Nowadays no researches has been performed on fatty acid profile (FA) and desaturase activity in metabolically healthy obesity (MHO). The aim of this study was…”
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Gangliosides influence EGFR/ErbB2 heterodimer stability but they do not modify EGF-dependent ErbB2 phosphorylation by Milani, Simona, Sottocornola, Elena, Zava, Stefania, Galbiati, Mariarita, Berra, Bruno, Colombo, Irma

“…Gangliosides are well-known regulators of cell differentiation through specific interactions with growth factor receptors. Previously, our group provided the…”
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Human GM3 synthase: a new mRNA variant encodes an NH2-terminal extended form of the protein by Berselli, Patrizia, Zava, Stefania, Sottocornola, Elena, Milani, Simona, Berra, Bruno, Colombo, Irma

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Ganglioside GM3 is stably associated to tyrosine-phosphorylated ErbB2/EGFR receptor complexes and EGFR monomers, but not to ErbB2 by Milani, Simona, Sottocornola, Elena, Zava, Stefania, Berselli, Patrizia, Berra, Bruno, Colombo, Irma

“…Gangliosides are known to modulate the activation of receptor tyrosine-kinases (RTKs). Recently, we demonstrated the functional relationship between ErbB2 and…”
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Ganglioside GM(3) is stably associated to tyrosine-phosphorylated ErbB2/EGFR receptor complexes and EGFR monomers, but not to ErbB2 by Milani, Simona, Sottocornola, Elena, Zava, Stefania, Berselli, Patrizia, Berra, Bruno, Colombo, Irma

“…Gangliosides are known to modulate the activation of receptor tyrosine-kinases (RTKs). Recently, we demonstrated the functional relationship between ErbB2 and…”
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Role of gangliosides in the association of ErbB2 with lipid rafts in mammary epithelial HC11 cells by Sottocornola, Elena, Misasi, Roberta, Mattei, Vincenzo, Ciarlo, Laura, Gradini, Roberto, Garofalo, Tina, Berra, Bruno, Colombo, Irma, Sorice, Maurizio

“…We analyzed the role of gangliosides in the association of the ErbB2 receptor tyrosine‐kinase (RTK) with lipid rafts in mammary epithelial HC11 cells. Scanning…”
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GM3 content modulates the EGF-activated p185c-neu levels, but not those of the constitutively activated oncoprotein p185neu by Sottocornola, Elena, Berra, Bruno, Colombo, Irma

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GM 3 content modulates the EGF-activated p185 c-neu levels, but not those of the constitutively activated oncoprotein p185 neu by Sottocornola, Elena, Berra, Bruno, Colombo, Irma

“…The functional relationship between ganglioside GM 3 and two tyrosine-kinase receptors, the normal protein p185 c-neu and the mutant oncogenic protein p185…”
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Stable transfection of human β-1,4N-acetylgalactosaminyltransferase and α-2,8-sialyltransferase cDNAs in C6 rat glioma cells induces modifications in ganglioside metabolism by Sottocornola, Elena, Colombo, Irma, Berra, Bruno

“…Ganglioside distribution in cells undergoes deep modifications during physiological and pathological events, possibly depending on the activity of…”
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The primary structure of UK114 tumor antigen by Ceciliani, F, Faotto, L, Negri, A, Colombo, I, Berra, B, Bartorelli, A, Ronchi, S

“…UK114 is a tumor antigen expressed by various malignant neoplasms. The complete amino acid sequence of UK114 purified from goat liver has been determined by…”
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