Search Results - "COLMEGNA, PATRICIO"
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Switched LPV Glucose Control in Type 1 Diabetes
Published in IEEE transactions on biomedical engineering (01-06-2016)“…Objective: The purpose of this paper is to regulate the blood glucose level in Type 1 Diabetes Mellitus patients with a practical and flexible procedure that…”
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Editorial: Recent Advances in Computer Simulation for Diabetes Treatment and Care
Published in Frontiers in endocrinology (Lausanne) (23-05-2022)Get full text
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Reducing Glucose Variability Due to Meals and Postprandial Exercise in T1DM Using Switched LPV Control: In Silico Studies
Published in Journal of diabetes science and technology (01-05-2016)“…Background: Time-varying dynamics is one of the main issues for achieving safe blood glucose control in type 1 diabetes mellitus (T1DM) patients. In addition,…”
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Mapping data to virtual patients in type 1 diabetes
Published in Control engineering practice (01-10-2020)“…In this work, a new approach to represent dynamic variations in type 1 diabetes (T1D) leveraging field-collected data (glucose monitor, insulin pump and meal…”
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Automatic regulatory control in type 1 diabetes without carbohydrate counting
Published in Control engineering practice (01-05-2018)“…A new approach to automatically regulate the glucose level in type 1 diabetes is presented in this work. This is the so-called Automatic Regulation of Glucose…”
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Validation of the UVA Simulation Replay Methodology Using Clinical Data: Reproducing a Randomized Clinical Trial
Published in Diabetes technology & therapeutics (01-10-2024)“…Computer simulators of human metabolism are powerful tools to design and validate new diabetes treatments. However, these platforms are often limited in the…”
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Advanced hybrid artificial pancreas system improves on unannounced meal response - In silico comparison to currently available system
Published in Computer methods and programs in biomedicine (01-11-2021)“…•Advanced hybrid closed-loop control offers flexibility on announced/unannounced meals.•Improved glycemic control over unannounced meals in comparison to a…”
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Control-Oriented Model With Intra-Patient Variations for an Artificial Pancreas
Published in IEEE journal of biomedical and health informatics (01-09-2020)“…In this work, a low-order model designed for glucose regulation in Type 1 Diabetes Mellitus (T1DM) is obtained from the UVA/Padova metabolic simulator. It…”
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Evaluation of a Web-Based Simulation Tool for Self-Management Support in Type 1 Diabetes: A Pilot Study
Published in IEEE journal of biomedical and health informatics (01-01-2023)“…Objective: To develop and evaluate a novel Web-based Simulation Tool (WST) that brings simulation technologies to people with Type 1 Diabetes (T1D), enabling…”
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Replay Simulations with Personalized Metabolic Model for Treatment Design and Evaluation in Type 1 Diabetes
Published in Journal of diabetes science and technology (01-11-2021)“…Background: The capacity to replay data collected in real life by people with type 1 diabetes mellitus (T1DM) would lead to individualized (vs population)…”
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Impact of Accelerating Insulin on an Artificial Pancreas System Without Meal Announcement: An In Silico Examination
Published in Journal of diabetes science and technology (01-07-2021)“…Background: Controlling postprandial blood glucose without the benefit of an appropriately sized premeal insulin bolus has been challenging given the delays in…”
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Integration of a Safety Module to Prevent Rebound Hypoglycemia in Closed-Loop Artificial Pancreas Systems
Published in Journal of diabetes science and technology (01-03-2024)“…Background: With automated insulin delivery (AID) systems becoming widely adopted in the management of type 1 diabetes, we have seen an increase in occurrences…”
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Adaptive Biobehavioral Control: A Pilot Analysis of Human-Machine Coadaptation in Type 1 Diabetes
Published in Diabetes technology & therapeutics (01-09-2024)“…While it is well recognized that an automated insulin delivery (AID) algorithm should adapt to changes in physiology, it is less understood that the individual…”
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783-P: When Automated Insulin Delivery Technology Meets Behavior: A Pilot Exploration of Human-Machine Coadaptation in Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Background: Automated Insulin Delivery (AID) devices in type 1 diabetes (T1D) are becoming standard of care, and the need for adaptive AID systems is now well…”
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Simulation-driven optimization of insulin therapy profiles in a commercial hybrid closed-loop system
Published in Computer methods and programs in biomedicine (01-12-2023)“…Automated insulin delivery (AID) has represented a breakthrough in managing type 1 diabetes (T1D), showing safe and effective glucose control extensively…”
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Maximizing Glycemic Benefits of Using Faster Insulin Formulations in Type 1 Diabetes: In Silico Analysis Under Open- and Closed-Loop Conditions
Published in Diabetes technology & therapeutics (01-04-2023)“…Ultrarapid-acting insulin analogs that could improve or even prevent postprandial hyperglycemia are now available for both research and clinical care. However,…”
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Artificial Pancreas: Evaluating the ARG Algorithm Without Meal Announcement
Published in Journal of diabetes science and technology (01-11-2019)“…Background: Either under standard basal-bolus treatment or hybrid closed-loop control, subjects with type 1 diabetes are required to count carbohydrates…”
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Assessment of Meal Anticipation for Improving Fully Automated Insulin Delivery in Adults With Type 1 Diabetes
Published in Diabetes care (01-09-2023)“…Meals are a consistent challenge to glycemic control in type 1 diabetes (T1D). Our objective was to assess the glycemic impact of meal anticipation within a…”
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97-LB: Bringing Simulation Technologies to People with T1D: A Pilot Study
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Background: Researchers have extensively used metabolic simulators as a fast, inexpensive, and safe way of testing novel treatment strategies. This work aims…”
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Reducing risks in type 1 diabetes using H∞ control
Published in IEEE transactions on biomedical engineering (01-12-2014)“…A control scheme was designed in order to reduce the risks of hyperglycemia and hypoglycemia in type 1 diabetes mellitus (T1DM). This structure is composed of…”
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