Search Results - "COLLINS, Helen"
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Female cardiovascular biology and resilience in the setting of physiological and pathological stress
Published in Redox biology (01-07-2023)“…For years, females were thought of as smaller men with complex hormonal cycles; as a result, females have been largely excluded from preclinical and clinical…”
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Rodent Models of Alzheimer's Disease: Past Misconceptions and Future Prospects
Published in International journal of molecular sciences (01-06-2024)“…Alzheimer's disease (AD) is a progressive neurodegenerative disease with no effective treatments, not least due to the lack of authentic animal models…”
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3
Workplace Support for Newly Qualified Doctors and Secondary School Teachers: A Comparative Analysis
Published in British educational research journal (01-10-2023)“…Doctors and teachers in their first year of practice face steep learning curves and increased stress, which can induce poor mental health, burnout and…”
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4
Regulation of cardiac O-GlcNAcylation: More than just nutrient availability
Published in Biochimica et biophysica acta. Molecular basis of disease (01-05-2020)“…The post-translational modification of serine and threonine residues of nuclear, cytosolic, and mitochondrial proteins by O-linked β-N-acetyl glucosamine…”
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O-GlcNAcylation and cardiovascular disease
Published in Biochemical Society transactions (15-04-2017)“…The post-translational modification of serine and threonine residues of proteins found in numerous subcellular locations by -linked -acetylglucosamine (…”
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Protein O-GlcNAcylation and Cardiovascular (Patho)physiology
Published in The Journal of biological chemistry (12-12-2014)“…Our understanding of the role of protein O-GlcNAcylation in the regulation of the cardiovascular system has increased rapidly in recent years. Studies have…”
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7
Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response
Published in PloS one (19-08-2015)“…Hepatic expression of iron homeostasis genes and serum iron parameters predict the success of immunosuppression withdrawal following clinical liver…”
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8
Revised Phylogeny of the Cellulose Synthase Gene Superfamily: Insights into Cell Wall Evolution
Published in Plant physiology (Bethesda) (01-07-2018)“…Cell walls are crucial for the integrity and function of all land plants and are of central importance in human health, livestock production, and as a source…”
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STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathology
Published in American journal of physiology. Heart and circulatory physiology (15-08-2013)“…Store-operated Ca²⁺ entry (SOCE) is critical for Ca²⁺ signaling in nonexcitable cells; however, its role in the regulation of cardiomyocyte Ca²⁺ homeostasis…”
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10
The impact of resistance training on strength and correlates of physical activity in youth
Published in Journal of sports sciences (2022)“…Resistance training (RT) may have a positive impact on specific correlates of physical activity (PA) in inactive and/or obese youth, with strength as a…”
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11
Quantitative structural organisation model for wheat endosperm cell walls: Cellulose as an important constituent
Published in Carbohydrate polymers (15-09-2018)“…[Display omitted] •Cellulose is a significant constituent of wheat endosperm cell walls.•Wheat endosperm cell walls have low levels of ferulic acid…”
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12
Rebound activation of 5-HT neurons following SSRI discontinuation
Published in Neuropsychopharmacology (New York, N.Y.) (01-09-2024)“…Cessation of therapy with a selective serotonin (5-HT) reuptake inhibitor (SSRI) is often associated with an early onset and disabling discontinuation…”
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13
Cardiac mitochondrial metabolism during pregnancy and the postpartum period
Published in American journal of physiology. Heart and circulatory physiology (01-05-2024)“…The goal of the present study was to characterize changes in mitochondrial respiration in the maternal heart during pregnancy and after birth. Timed pregnancy…”
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14
Withholding iron as a cellular defence mechanism - friend or foe
Published in European journal of immunology (01-07-2008)“…During infection one critical host defence strategy is an attempt to withhold iron from invading pathogens. This is achieved by by proinflammatory cytokines…”
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15
Continuous home cage monitoring of activity and sleep in mice during repeated paroxetine treatment and discontinuation
Published in Psychopharmacology (01-11-2023)“…Rationale Non-invasive home cage monitoring is emerging as a valuable tool to assess the effects of experimental interventions on mouse behaviour. A field in…”
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Cardiomyocyte-Specific BMAL1 Plays Critical Roles in Metabolism, Signaling, and Maintenance of Contractile Function of the Heart
Published in Journal of biological rhythms (01-08-2014)“…Circadian clocks are cell autonomous, transcriptionally based, molecular mechanisms that confer the selective advantage of anticipation, enabling cells/organs…”
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Exercise-induced changes in myocardial glucose utilization during periods of active cardiac growth
Published in Journal of molecular and cellular cardiology (01-06-2024)“…Exercise training can promote physiological cardiac growth, which has been suggested to involve changes in glucose metabolism to facilitate hypertrophy of…”
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Effect of selective serotonin reuptake inhibitor discontinuation on anxiety-like behaviours in mice
Published in Journal of psychopharmacology (Oxford) (01-07-2022)“…Background: Abrupt cessation of therapy with a selective serotonin reuptake inhibitor (SSRI) is associated with a discontinuation syndrome, typified by…”
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19
Transcriptional and biochemical analyses of gibberellin expression and content in germinated barley grain
Published in Journal of experimental botany (25-03-2020)“…Abstract Mobilization of reserves in germinated cereal grains is critical for early seedling vigour, global crop productivity, and hence food security…”
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A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis
Published in Haematologica (Roma) (01-01-2017)“…Momelotinib, a small-molecule inhibitor of Janus kinase 1 and Janus kinase 2, has demonstrated efficacy in myelofibrosis patients with 300 mg, once-daily…”
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