Search Results - "COLLINO, Massimo"

Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin by Collino, Massimo, Thiemermann, Christoph, Cerami, Anthony, Brines, Michael

“…Many disease processes activate a cellular stress response that initiates a cascade of inflammation and damage. However, this process also triggers a tissue…”
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Redox Signaling and Advanced Glycation Endproducts (AGEs) in Diet-Related Diseases by Cepas, Vanesa, Collino, Massimo, Mayo, Juan C, Sainz, Rosa M

“…Diets are currently characterized by elevated sugar intake, mainly due to the increased consumption of processed sweetened foods and drinks during the last 40…”
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Editorial: Sphingolipids in cardiovascular diseases: from pathogenesis to therapeutics by Collino, Massimo, Piccoli, Marco

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Recent advances in JAK inhibitors for the treatment of metabolic syndrome by Collotta, Debora, Franchina, Maria Paola, Carlucci, Virginia, Collino, Massimo

“…With an epidemic spread, metabolic syndrome represents an increasingly emerging risk for the population globally, and is currently recognized as a pathological…”
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Effects of vitamin D on insulin resistance and myosteatosis in diet-induced obese mice by Benetti, Elisa, Mastrocola, Raffaella, Chiazza, Fausto, Nigro, Debora, D'Antona, Giuseppe, Bordano, Valentina, Fantozzi, Roberto, Aragno, Manuela, Collino, Massimo, Minetto, Marco Alessandro

“…Epidemiological studies pointed out to a strong association between vitamin D deficiency and type 2 diabetes prevalence. However, the role of vitamin D…”
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Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage by Aswani, Andrew, Manson, Joanna, Itagaki, Kiyoshi, Chiazza, Fausto, Collino, Massimo, Wupeng, Winston Liao, Chan, Tze Khee, Wong, W S Fred, Hauser, Carl J, Thiemermann, Chris, Brohi, Karim

“…Trauma is a leading cause of death worldwide with 5.8 million deaths occurring yearly. Almost 40% of trauma deaths are due to bleeding and occur in the first…”
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Editorial: Medicinal Cannabis: evolution of therapeutic use, future approaches and other implications, volume II by Baratta, Francesca, Ben-Shabat, Shimon, Brusa, Paola, Collino, Massimo

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Pharmacological Approaches to Modulate the Scarring Process after Glaucoma Surgery by Collotta, Debora, Colletta, Simona, Carlucci, Virginia, Fruttero, Claudia, Fea, Antonio Maria, Collino, Massimo

“…Glaucoma is an acquired optic neuropathy that results in a characteristic optic nerve head appearance and visual field loss. Reducing the IOP is the only…”
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Deletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems by Wouters, Kristiaan, Cento, Alessia S., Gaens, Katrien H., Teunissen, Margee, Scheijen, Jean L. J. M., Barutta, Federica, Chiazza, Fausto, Collotta, Debora, Aragno, Manuela, Gruden, Gabriella, Collino, Massimo, Schalkwijk, Casper G., Mastrocola, Raffaella

“…Advanced glycation endproducts (AGEs) are involved in several diseases, including NAFLD and NASH. RAGE is the main receptor mediating the pro-inflammatory…”
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Spleen tyrosine kinase: a novel pharmacological target for sepsis-induced cardiac dysfunction and multi-organ failure by Verra, Chiara, Paulmann, Maria Kerstin, Wegener, Jamila, Marzani, Enrica, Ferreira Alves, Gustavo, Collino, Massimo, Coldewey, Sina Maren, Thiemermann, Christoph

“…Sepsis is a systemic condition caused by a dysregulated host response to infection and often associated with excessive release of proinflammatory cytokines…”
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Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways by Bertinaria, Massimo, Pagliaro, Pasquale, Aragno, Manuela, Collino, Massimo, Cocco, Mattia, Alloatti, Giuseppe, Collotta, Debora, Serpe, Loredana, Chiazza, Fausto, Nigro, Debora, Penna, Claudia, Tullio, Francesca, Femminò, Saveria, Mastrocola, Raffaella

“…Although the nucleotide-binding oligomerization domain- (NOD-) like receptor pyrin domain containing 3 (NLRP3) inflammasome has been recently detected in the…”
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High dietary fructose intake: Sweet or bitter life? by Collino, Massimo

“…Epidemiological data show that the consumption of added sugars as ingredients in processed or prepared foods and caloric beverages has dramatically increased…”
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Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R by Sivarajah, Ahila, Collino, Massimo, Yasin, Mohammed, Benetti, Elisa, Gallicchio, Margherita, Mazzon, Emanuela, Cuzzocrea, Salvatore, Fantozzi, Roberto, Thiemermann, Christoph

“…Hydrogen sulfide (H2S) is a novel gaseous mediator produced by cystathionine-beta-synthase and cystathionine-gamma-lyase in the cardiovascular system,…”
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Exploring extra dimensions to capture saliva metabolite fingerprints from metabolically healthy and unhealthy obese patients by comprehensive two-dimensional gas chromatography featuring Tandem Ionization mass spectrometry by Cialiè Rosso, Marta, Stilo, Federico, Squara, Simone, Liberto, Erica, Mai, Stefania, Mele, Chiara, Marzullo, Paolo, Aimaretti, Gianluca, Reichenbach, Stephen E., Collino, Massimo, Bicchi, Carlo, Cordero, Chiara

“…This study examines the information potential of comprehensive two-dimensional gas chromatography combined with time-of-flight mass spectrometry (GC×GC-TOF MS)…”
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Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis by Coldewey, Sina M., Benetti, Elisa, Collino, Massimo, Pfeilschifter, Josef, Sponholz, Christoph, Bauer, Michael, Huwiler, Andrea, Thiemermann, Christoph

“…Serum levels of the lipid mediator sphingosine-1-phosphate (S1P) are reduced in septic patients and are inversely associated with disease severity. We show…”
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Effects of Exogenous Dietary Advanced Glycation End Products on the Cross-Talk Mechanisms Linking Microbiota to Metabolic Inflammation by Mastrocola, Raffaella, Collotta, Debora, Gaudioso, Giulia, Le Berre, Marie, Cento, Alessia Sofia, Ferreira Alves, Gustavo, Chiazza, Fausto, Verta, Roberta, Bertocchi, Ilaria, Manig, Friederike, Hellwig, Michael, Fava, Francesca, Cifani, Carlo, Aragno, Manuela, Henle, Thomas, Joshi, Lokesh, Tuohy, Kieran, Collino, Massimo

“…Heat-processed diets contain high amounts of advanced glycation end products (AGEs). Here we explore the impact of an AGE-enriched diet on markers of metabolic…”
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Editorial: Medicinal Cannabis: Evolution of therapeutic use, future approaches and other implications by Brusa, Paola, Baratta, Francesca, Collino, Massimo, Ben -Shabat, Shimon

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RETRACTED: Baricitinib protects mice from sepsis-induced cardiac dysfunction and multiple-organ failure by Verra, Chiara, Mohammad, Shireen, Alves, Gustavo Ferreira, Porchietto, Elisa, Coldewey, Sina Maren, Collino, Massimo, Thiemermann, Christoph

“…Sepsis is one of the major complications of surgery resulting in high morbidity and mortality, but there are no specific therapies for sepsis-induced organ…”
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RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis by Mohammad, Shireen, O’Riordan, Caroline E., Verra, Chiara, Aimaretti, Eleonora, Alves, Gustavo Ferreira, Dreisch, Klaus, Evenäs, Johan, Gena, Patrizia, Tesse, Angela, Rützler, Michael, Collino, Massimo, Calamita, Giuseppe, Thiemermann, Christoph

“…Sepsis is caused by systemic infection and is a major health concern as it is the primary cause of death from infection. It is the leading cause of mortality…”
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Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis by Cannito, Stefania, Morello, Elisabetta, Bocca, Claudia, Foglia, Beatrice, Benetti, Elisa, Novo, Erica, Chiazza, Fausto, Rogazzo, Mara, Fantozzi, Roberto, Povero, Davide, Sutti, Salvatore, Bugianesi, Elisabetta, Feldstein, Ariel E, Albano, Emanuele, Collino, Massimo, Parola, Maurizio

“…Non-Alcoholic Fatty Liver Disease (NAFLD) is a major form of chronic liver disease in the general population in relation to its high prevalence among…”
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