Search Results - "COLLIER, John"
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Atomic structure of anthrax protective antigen pore elucidates toxin translocation
Published in Nature (London) (28-05-2015)“…Cryo-electron microscopy determination of anthrax toxin protective antigen pore structure at a resolution of 2.9 Å, revealing the catalytic Φ-clamp and the…”
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The essential genome of a bacterium
Published in Molecular systems biology (30-08-2011)“…Caulobacter crescentus is a model organism for the integrated circuitry that runs a bacterial cell cycle. Full discovery of its essential genome, including…”
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Anthrax toxin: receptor binding, internalization, pore formation, and translocation
Published in Annual review of biochemistry (01-01-2007)“…Anthrax toxin consists of three nontoxic proteins that self-assemble at the surface of receptor-bearing mammalian cells or in solution, yielding a series of…”
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DiPOLE: a 10 J, 10 Hz cryogenic gas cooled multi-slab nanosecond Yb:YAG laser
Published in Optics express (27-07-2015)“…The Diode Pumped Optical Laser for Experiments (DiPOLE) project at the Central Laser Facility aims to develop a scalable, efficient high pulse energy diode…”
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Chemical and Physicochemical Pretreatment of Lignocellulosic Biomass: A Review
Published in Enzyme Research (2011)“…Overcoming the recalcitrance (resistance of plant cell walls to deconstruction) of lignocellulosic biomass is a key step in the production of fuels and…”
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Demonstration of stable, long-term operation of a nanosecond pulsed DPSSL at 10 J, 100 Hz
Published in Optics express (25-03-2024)“…We report on stable, long-term operation of a diode-pumped solid-state laser (DPSSL) amplifying 15 ns pulses at 1029.5 nm wavelength to 10 J energy at 100 Hz…”
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Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons
Published in Nature neuroscience (01-02-2022)“…Bacterial products can act on neurons to alter signaling and function. In the present study, we found that dorsal root ganglion (DRG) sensory neurons are…”
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ANTHRAX TOXIN
Published in Annual review of cell and developmental biology (01-01-2003)“…Anthrax toxin consists of three nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells…”
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Modelling and measurement of thermal stress-induced depolarisation in high energy, high repetition rate diode-pumped Yb:YAG lasers
Published in Optics express (15-02-2021)“…In this paper, we present a model to predict thermal stress-induced birefringence in high energy, high repetition rate diode-pumped Yb:YAG lasers. The model…”
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Receptor-directed chimeric toxins created by sortase-mediated protein fusion
Published in Molecular cancer therapeutics (01-10-2013)“…Chimeric protein toxins that act selectively on cells expressing a designated receptor may serve as investigational probes and/or antitumor agents. Here, we…”
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Femoral Stem Fracture and In Vivo Corrosion of Retrieved Modular Femoral Hips
Published in The Journal of arthroplasty (01-08-2012)“…Abstract A series of 78 retrieved modular hip devices were assessed for fretting and corrosion. Damage was common at both the head-neck junction (54% showing…”
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Changing the receptor specificity of anthrax toxin
Published in mBio (2012)“…The actions of many bacterial toxins depend on their ability to bind to one or more cell-surface receptors. Anthrax toxin acts by a sequence of events that…”
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Knee Wear Measured in Retrievals: A Polished Tray Reduces Insert Wear
Published in Clinical orthopaedics and related research (01-07-2012)“…Background Polyethylene wear is often cited as the cause of failure of TKA. Rotating platform (RP) knees show notable surface damage on the rotating surface…”
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Building more resilient communities with a wildfire preparedness drill in the U.S.: Individual and community influences and communication practices
Published in Journal of contingencies and crisis management (01-03-2023)“…When a wildfire strikes, it impacts entire communities. Yet it can be challenging to get communities to take the lead in becoming more prepared, and thus build…”
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A novel, safe, fast and efficient treatment for Her2‐positive and negative bladder cancer utilizing an EGF‐anthrax toxin chimera
Published in International journal of cancer (15-01-2020)“…Bladder cancer is the sixth most common cancer in the United States, and it exhibits an alarming 70% recurrence rate. Thus, the development of more efficient…”
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Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient
Published in Journal of molecular biology (03-02-2006)“…Protective antigen (PA) from anthrax toxin assembles into a homoheptamer on cell surfaces and forms complexes with the enzymatic components: lethal factor (LF)…”
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Gamma-irradiation Sterilization in an Inert Environment: A Partial Solution
Published in Clinical orthopaedics and related research (01-07-2012)“…Background In the mid to late 1990s, to sterilize UHMWPE bearings, manufacturers changed from gamma-irradiation-in-air (gamma-air) sterilization, which…”
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Improving coherent contrast of petawatt laser pulses
Published in Optics express (31-01-2011)“…We report on an experimental study of the "coherent" contrast feature that frequently appears in petawatt(PW)-class laser pulses as an exponentially-rising…”
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