Search Results - "COLL, P"

POMC: The Physiological Power of Hormone Processing by Harno, Erika, Gali Ramamoorthy, Thanuja, Coll, Anthony P, White, Anne

“…Pro-opiomelanocortin (POMC) is the archetypal polypeptide precursor of hormones and neuropeptides. In this review, we examine the variability in the individual…”
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Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity by Flint, Thomas R., Janowitz, Tobias, Connell, Claire M., Roberts, Edward W., Denton, Alice E., Coll, Anthony P., Jodrell, Duncan I., Fearon, Douglas T.

“…In patients with cancer, the wasting syndrome, cachexia, is associated with caloric deficiency. Here, we describe tumor-induced alterations of the host…”
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GDF15 mediates the effects of metformin on body weight and energy balance by Coll, Anthony P., Chen, Michael, Taskar, Pranali, Rimmington, Debra, Patel, Satish, Tadross, John A., Cimino, Irene, Yang, Ming, Welsh, Paul, Virtue, Samuel, Goldspink, Deborah A., Miedzybrodzka, Emily L., Konopka, Adam R., Esponda, Raul Ruiz, Huang, Jeffrey T.-J., Tung, Y. C. Loraine, Rodriguez-Cuenca, Sergio, Tomaz, Rute A., Harding, Heather P., Melvin, Audrey, Yeo, Giles S. H., Preiss, David, Vidal-Puig, Antonio, Vallier, Ludovic, Nair, K. Sreekumaran, Wareham, Nicholas J., Ron, David, Gribble, Fiona M., Reimann, Frank, Sattar, Naveed, Savage, David B., Allan, Bernard B., O’Rahilly, Stephen

“…Metformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk 1 , 2 . More than 60% of this…”
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The Prevention of Infections in Older Adults: Oral Health by Coll, Patrick P., Lindsay, Adam, Meng, Joyce, Gopalakrishna, Aadarsh, Raghavendra, Sree, Bysani, Pooja, O'Brien, Daniel

“…The oral cavity is exposed to the external environment and from a very young age is colonized by infectious agents. Under certain circumstances including poor…”
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Healthy Aging: American Geriatrics Society White Paper Executive Summary by Friedman, Susan M., Mulhausen, Paul, Cleveland, Maryjo L., Coll, Patrick P., Daniel, Kathryn M., Hayward, Arthur D., Shah, Krupa, Skudlarska, Beata, White, Heidi K.

“…In July 2015, the Journal of the American Geriatrics Society published a manuscript titled, “Failing to Focus on Healthy Aging: A Frailty of Our Discipline?”…”
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How to: identify non-tuberculous Mycobacterium species using MALDI-TOF mass spectrometry by Alcaide, F., Amlerová, J., Bou, G., Ceyssens, P.J., Coll, P., Corcoran, D., Fangous, M.-S., González-Álvarez, I., Gorton, R., Greub, G., Hery-Arnaud, G., Hrábak, J., Ingebretsen, A., Lucey, B., Marekoviċ, I., Mediavilla-Gradolph, C., Monté, M.R., O'Connor, J., O'Mahony, J., Opota, O., O'Reilly, B., Orth-Höller, D., Oviaño, M., Palacios, J.J., Palop, B., Pranada, A.B., Quiroga, L., Rodríguez-Temporal, D., Ruiz-Serrano, M.J., Tudó, G., Van den Bossche, A., van Ingen, J., Rodriguez-Sanchez, B.

“…The implementation of MALDI-TOF MS for microorganism identification has changed the routine of the microbiology laboratories as we knew it. Most microorganisms…”
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Obesity and FTO: Changing Focus at a Complex Locus by Tung, Y.C. Loraine, Yeo, Giles S.H., O’Rahilly, Stephen, Coll, Anthony P.

“…The fat mass and obesity-associated (FTO) gene was placed center stage when common intronic variants within the gene were robustly associated with human…”
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The Hormonal Control of Food Intake by Coll, Anthony P., Farooqi, I. Sadaf, O'Rahilly, Stephen

“…Numerous circulating peptides and steroids produced in the body influence appetite through their actions on the hypothalamus, the brain stem, and the autonomic…”
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Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells by Yang, Ming, Darwish, Tamana, Larraufie, Pierre, Rimmington, Debra, Cimino, Irene, Goldspink, Deborah A., Jenkins, Benjamin, Koulman, Albert, Brighton, Cheryl A., Ma, Marcella, Lam, Brian Y. H., Coll, Anthony P., O’Rahilly, Stephen, Reimann, Frank, Gribble, Fiona M.

“…Even though metformin is widely used to treat type2 diabetes, reducing glycaemia and body weight, the mechanisms of action are still elusive. Recent studies…”
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Adult onset global loss of the fto gene alters body composition and metabolism in the mouse by McMurray, Fiona, Church, Chris D, Larder, Rachel, Nicholson, George, Wells, Sara, Teboul, Lydia, Tung, Y C Loraine, Rimmington, Debra, Bosch, Fatima, Jimenez, Veronica, Yeo, Giles S H, O'Rahilly, Stephen, Ashcroft, Frances M, Coll, Anthony P, Cox, Roger D

“…The strongest BMI-associated GWAS locus in humans is the FTO gene. Rodent studies demonstrate a role for FTO in energy homeostasis and body composition. The…”
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Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats by Tung, Yi-Chun Loraine, Ayuso, Eduard, Shan, Xiaoye, Bosch, Fatima, O'Rahilly, Stephen, Coll, Anthony P, Yeo, Giles S.H

“…Sequence variants in the first intron of FTO are strongly associated with human obesity and human carriers of the risk alleles show evidence for increased…”
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The Prevention of Cardiovascular Disease in Older Adults by Coll, Patrick P., Roche, Vivyenne, Olsen, Jaclyn S., Voit, Jessica H., Bowen, Emily, Kumar, Manish

“…Cardiovascular disease (CVD) is common in older adults. CVD is a significant cause of both death and disability in old age. Though the prevention and treatment…”
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Organic molecules in the Sheepbed Mudstone, Gale Crater, Mars by Freissinet, C., Glavin, D. P., Mahaffy, P. R., Miller, K. E., Eigenbrode, J. L., Summons, R. E., Brunner, A. E., Buch, A., Szopa, C., Archer, P. D., Franz, H. B., Atreya, S. K., Brinckerhoff, W. B., Cabane, M., Coll, P., Conrad, P. G., Des Marais, D. J., Dworkin, J. P., Fairén, A. G., François, P., Grotzinger, J. P., Kashyap, S., Kate, I. L., Leshin, L. A., Malespin, C. A., Martin, M. G., Martin‐Torres, F. J., McAdam, A. C., Ming, D. W., Navarro‐González, R., Pavlov, A. A., Prats, B. D., Squyres, S. W., Steele, A., Stern, J. C., Sumner, D. Y., Sutter, B., Zorzano, M.‐P.

“…The Sample Analysis at Mars (SAM) instrument on board the Mars Science Laboratory Curiosity rover is designed to conduct inorganic and organic chemical…”
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Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15 by Cimino, Irene, Kim, Hanna, Tung, Y. C. Loraine, Pedersen, Kent, Rimmington, Debra, Tadross, John A., Kohnke, Sara N., Neves-Costa, Ana, Barros, André, Joaquim, Stephanie, Bennett, Don, Melvin, Audrey, Lockhart, Samuel M., Rostron, Anthony J., Scott, Jonathan, Liu, Hui, Burling, Keith, Barker, Peter, Clatworthy, Menna R., Lee, E-Chiang, Simpson, A. John, Yeo, Giles S. H., Moita, Luís F., Bence, Kendra K., Jørgensen, Sebastian Beck, Coll, Anthony P., Breen, Danna M., O’Rahilly, Stephen

“…An acute increase in the circulating concentration of glucocorticoid hormones is essential for the survival of severe somatic stresses. Circulating…”
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Volatile, Isotope, and Organic Analysis of Martian Fines with the Mars Curiosity Rover by Leshin, L. A., Mahaffy, P. R., Webster, C. R., Cabane, M., Coll, P., Conrad, P. G., Archer, P. D., Atreya, S. K., Brunner, A. E., Buch, A., Eigenbrode, J. L., Flesch, G. J., Franz, H. B., Freissinet, C., Glavin, D. P., McAdam, A. C., Miller, K. E., Ming, D. W., Morris, R. V., Navarro-González, R., Niles, P. B., Owen, T., Pepin, R. O., Squyres, S., Steele, A., Stern, J. C., Summons, R. E., Sumner, D. Y., Sutter, B., Szopa, C., Teinturier, S., Trainer, M. G., Wray, J. J., Grotzinger, J. P.

“…Samples from the Rocknest aeolian deposit were heated to ~835°C under helium flow and evolved gases analyzed by Curiosity's Sample Analysis at Mars instrument…”
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PET Oncological Radiopharmaceuticals: Current Status and Perspectives by Lin, Mai, Coll, Ryan P, Cohen, Allison S, Georgiou, Dimitra K, Manning, Henry Charles

“…Molecular imaging is the visual representation of biological processes that take place at the cellular or molecular level in living organisms. To date,…”
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Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity by Dalgaard, Kevin, Landgraf, Kathrin, Heyne, Steffen, Lempradl, Adelheid, Longinotto, John, Gossens, Klaus, Ruf, Marius, Orthofer, Michael, Strogantsev, Ruslan, Selvaraj, Madhan, Lu, Tess Tsai-Hsiu, Casas, Eduard, Teperino, Raffaele, Surani, M. Azim, Zvetkova, Ilona, Rimmington, Debra, Tung, Y.C. Loraine, Lam, Brian, Larder, Rachel, Yeo, Giles S.H., O’Rahilly, Stephen, Vavouri, Tanya, Whitelaw, Emma, Penninger, Josef M., Jenuwein, Thomas, Cheung, Ching-Lung, Ferguson-Smith, Anne C., Coll, Anthony P., Körner, Antje, Pospisilik, J. Andrew

“…More than one-half billion people are obese, and despite progress in genetic research, much of the heritability of obesity remains enigmatic. Here, we identify…”
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Experimental phase function and degree of linear polarization of cometary dust analogues by Frattin, E, Muñoz, O, Moreno, F, Nava, J, Escobar-Cerezo, J, Gomez Martin, J C, Guirado, D, Cellino, A, Coll, P, Raulin, F, Bertini, I, Cremonese, G, Lazzarin, M, Naletto, G, La Forgia, F

“…We present experimental phase function and degree of linear polarization curves for seven samples of cometary dust analogues namely: ground pieces of Allende,…”
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Oxidants at the Surface of Mars: A Review in Light of Recent Exploration Results by Lasne, J, Noblet, A, Szopa, C, Navarro-González, R, Cabane, M, Poch, O, Stalport, F, François, P, Atreya, S K, Coll, P

“…In 1976, the Viking landers carried out the most comprehensive search for organics and microbial life in the martian regolith. Their results indicate that…”
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Time trends in the aetiology of prosthetic joint infections: a multicentre cohort study by Benito, N., Franco, M., Ribera, A., Soriano, A., Rodriguez-Pardo, D., Sorlí, L., Fresco, G., Fernández-Sampedro, M., Dolores del Toro, M., Guío, L., Sánchez-Rivas, E., Bahamonde, A., Riera, M., Esteban, J., Baraia-Etxaburu, J.M., Martínez-Alvarez, J., Jover-Sáenz, A., Dueñas, C., Ramos, A., Sobrino, B., Euba, G., Morata, L., Pigrau, C., Coll, P., Mur, I., Ariza, J., Barcenilla, F., Pérez-Villar, F., Prats-Gispert, L., Cisterna, R., Ibarra, S., López, Í., Santamaría, J.M., Cabo, J., García, D., Lora-Tamayo, J., Murillo, O., Pedrero, S., Álvarez-Parrondo, S., Muedra-Font, R., Raya-Fernández, C., Rodríguez-Alonso, C., Moreno, A., Blanco-Martínez-de-Morentin, M.A., Cabo-Magadan, R., Combalia, A., García, S., Martínez-Pastor, J.C., Tornero, E., Merino-Pérez, J., Montejo, J.M., Alier, A., Horcajada, J.P., Plasencia, V., Puig, L., Auñon, Á., Blanco, A., García-Cañete, J., Sandoval, E., Fakkas-Fernández, M., Garcés-Zarzalejo, C., Fariñas-Alvarez, C., Fariñas, M.C., Martinez-Martinez, L., Salas-Venero, C., Cobo, J., Ruiz-Carbajosa, P., Jordán, M., Crusi, X., Marinescu, C., Montaner, F., Ramírez, A., Corona, P.S., Lung, M., Muniain-Ezcurra, M.Á., Peñas-Espinar, C., Suárez, A.I., Álvarez, R., Cordero, J.-A., López-Pliego, M., Palomino, J., Puente, A.

“…It is important to know the spectrum of the microbial aetiology of prosthetic joint infections (PJIs) to guide empiric treatment and establish antimicrobial…”
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