Search Results - "COLE, Neil M"
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Effects of high- and low-velocity resistance training on the contractile properties of skeletal muscle fibers from young and older humans
Published in Journal of applied physiology (1985) (01-10-2011)“…A two-arm, prospective, randomized, controlled trial study was conducted to investigate the effects of movement velocity during progressive resistance training…”
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Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity
Published in Nature (London) (19-08-1993)“…Duchenne and Becker muscular dystrophy (DMD and BMD) are X-linked recessive diseases caused by defective expression of dystrophin. The mdx mouse, an animal…”
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Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice
Published in Human molecular genetics (01-08-1995)“…Duchenne and Becker muscular dystrophy are caused by defects in the dystrophin gene, and are candidates for treatment by gene therapy. We have shown previously…”
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Transgenic mdx Mice Expressing Dystrophin with a Deletion in the Actin-Binding Domain Display a "Mild Becker" Phenotype
Published in The Journal of cell biology (01-08-1996)“…The functional significance of the actin-binding domain of dystrophin, the protein lacking in patients with Duchenne muscular dystrophy, has remained elusive…”
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Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice
Published in The American journal of physiology (01-06-1997)“…Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control…”
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Muscle sounds are emitted at the resonant frequencies of skeletal muscle
Published in IEEE transactions on biomedical engineering (01-05-1990)“…The changes in mechanical resonant frequency of whole muscles during twitch and tetanic contractions are compared to changes in frequency components of the…”
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Prevention of dystrophic pathology in mdx mice by a truncated dystrophin isoform
Published in Human molecular genetics (01-10-1994)“…The C-terminal domain of dystrophin is alternatively spliced to produce a variety of tissue and developmental stage-specific isoforms. Recent studies suggest…”
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