Search Results - "COLE, L"

Optogenetic self-stimulation in the nucleus accumbens: D1 reward versus D2 ambivalence by Cole, Shannon L, Robinson, Mike J F, Berridge, Kent C

“…The nucleus accumbens (NAc) contains multiple subpopulations of medium spiny neurons (MSNs). One subpopulation expresses D1-type dopamine receptors, another…”
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Nickel-catalyzed reductive coupling of unactivated alkyl bromides and aliphatic aldehydes by Cruz, Cole L, Montgomery, John

“…A mild, convenient coupling of aliphatic aldehydes and unactivated alkyl bromides has been developed. The catalytic system features the use of a common Ni( ii…”
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"The Weight of Choices" by Bird, Cole L

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SpikeInterface, a unified framework for spike sorting by Buccino, Alessio P, Hurwitz, Cole L, Garcia, Samuel, Magland, Jeremy, Siegle, Joshua H, Hurwitz, Roger, Hennig, Matthias H

“…Much development has been directed toward improving the performance and automation of spike sorting. This continuous development, while essential, has…”
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Ambient-Temperature Newman–Kwart Rearrangement Mediated by Organic Photoredox Catalysis by Perkowski, Andrew J, Cruz, Cole L, Nicewicz, David A

“…The Newman–Kwart rearrangement is perhaps the quintessential method for the synthesis of thiophenols from the corresponding phenol. However, the high thermal…”
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Nucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis by Webb, Eric W, Park, John B, Cole, Erin L, Donnelly, David J, Bonacorsi, Samuel J, Ewing, William R, Doyle, Abigail G

“…We report a redox-neutral method for nucleophilic fluorination of N-hydroxyphthalimide esters using an Ir photocatalyst under visible light irradiation. The…”
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Enantioselective counter-anions in photoredox catalysis: The asymmetric cation radical Diels-Alder reaction by Morse, Peter D., Nguyen, Tien M., Cruz, Cole L., Nicewicz, David A.

“…Control of absolute stereochemistry in radical and ion radical transformations is a major challenge in synthetic chemistry. Herein, we report the design of a…”
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Validation of dual energy X-ray absorptiometry for longitudinal quantification of tumor burden in a murine model of pancreatic ductal adenocarcinoma by Sechrist, Zachary R, Lee, Grace, Schwarz, Edward M, Cole, Calvin L

“…Noninvasive imaging is central to preclinical, in vivo models of pancreatic ductal adenocarcinoma (PDAC). While bioluminescent imaging (BLI) is a gold…”
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Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetaemia: a descriptive study by Pritt, Bobbi S, MD, Mead, Paul S, MD, Johnson, Diep K Hoang, BS, Neitzel, David F, MS, Respicio-Kingry, Laurel B, MS, Davis, Jeffrey P, Prof, Schiffman, Elizabeth, MPH, Sloan, Lynne M, MT, Schriefer, Martin E, PhD, Replogle, Adam J, BS, Paskewitz, Susan M, Prof, Ray, Julie A, MPH, Bjork, Jenna, DVM, Steward, Christopher R, MPH, Deedon, Alecia, BS, Lee, Xia, MS, Kingry, Luke C, PhD, Miller, Tracy K, PhD, Feist, Michelle A, BS, Theel, Elitza S, PhD, Patel, Robin, Prof, Irish, Cole L, BS, Petersen, Jeannine M, PhD

“…Summary Background Lyme borreliosis is the most common tick-borne disease in the northern hemisphere. It is a multisystem disease caused by Borrelia…”
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Direct Detection of Influenza A and B Viruses in Less Than 20 Minutes Using a Commercially Available Rapid PCR Assay by Binnicker, Matthew J, Espy, Mark J, Irish, Cole L, Vetter, Emily A

“…We compared an FDA-cleared rapid (<20 min) PCR assay (Cobas Liat; Roche Diagnostics) to our routine influenza A and B real-time PCR assay (Simplexa Flu A/B &…”
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TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading by Martini-Stoica, Heidi, Cole, Allysa L, Swartzlander, Daniel B, Chen, Fading, Wan, Ying-Wooi, Bajaj, Lakshya, Bader, David A, Lee, Virginia M Y, Trojanowski, John Q, Liu, Zhandong, Sardiello, Marco, Zheng, Hui

“…The progression of tau pathology in Alzheimer's disease follows a stereotyped pattern, and recent evidence suggests a role of synaptic connections in this…”
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Non-invasive screening of breast cancer from fingertip smears—a proof of concept study by Russo, C., Wyld, L., Da Costa Aubreu, M., Bury, C. S., Heaton, C., Cole, L. M., Francese, S.

“…Breast cancer is a global health issue affecting 2.3 million women per year, causing death in over 600,000. Mammography (and biopsy) is the gold standard for…”
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Diagnostic accuracy of a lung ultrasound protocol (Vet BLUE) for detection of pleural fluid, pneumothorax and lung pathology in dogs and cats by Cole, L., Pivetta, M., Humm, K.

“…Objectives To assess the accuracy of the lung ultrasound protocol Vet BLUE, using thoracic CT as the reference standard, for the detection of thoracic…”
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Effects of steroid stewardship on glycemic control in acute exacerbations of chronic obstructive pulmonary disease patients by Cole, Jennifer L.

“…Introduction The adverse effects of corticosteroids are dose‐dependent, and guidance is to use the lowest effective dose in most disease states. The study…”
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Mechanistic Investigations into the Cation Radical Newman–Kwart Rearrangement by Cruz, Cole L, Nicewicz, David A

“…Efforts to elucidate the governing factors in the cation radical Newman–Kwart rearrangement are described. Through a combination of spectroscopic and kinetic…”
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Conceptualizing socio-emotional disablism: a duoethnography of Crohn's disease and OCD during COVID-19 by Cole, Kristen L., Lawless, Brandi

“…We utilize duoethnography to help readers better understand the constitutive nature of disability in the contexts of chronic illness and mental health. By…”
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Host Tropism and Structural Biology of ABC Toxin Complexes by Martin, Cole L, Hill, John H, Aller, Stephen G

“…ABC toxin complexes are a class of protein toxin translocases comprised of a multimeric assembly of protein subunits. Each subunit displays a unique…”
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Adding Insult to Injury: Mechanistic Basis for How AmpC Mutations Allow Pseudomonas aeruginosa To Accelerate Cephalosporin Hydrolysis and Evade Avibactam by Slater, Cole L, Winogrodzki, Judith, Fraile-Ribot, Pablo A, Oliver, Antonio, Khajehpour, Mazdak, Mark, Brian L

“…is a leading cause of nosocomial infections worldwide and notorious for its broad-spectrum resistance to antibiotics. A key mechanism that provides extensive…”
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Safety and tolerability of transcranial magnetic and direct current stimulation in children: Prospective single center evidence from 3.5 million stimulations by Zewdie, E., Ciechanski, P., Kuo, H.C., Giuffre, A., Kahl, C., King, R., Cole, L., Godfrey, H., Seeger, T., Swansburg, R., Damji, O., Rajapakse, T., Hodge, J., Nelson, S., Selby, B., Gan, L., Jadavji, Z., Larson, J.R., MacMaster, F., Yang, J.F., Barlow, K., Gorassini, M., Brunton, K., Kirton, A.

“…Non-invasive brain stimulation is being increasingly used to interrogate neurophysiology and modulate brain function. Despite the high scientific and…”
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Generic Price Competition For Specialty Drugs: Too Little, Too Late? by Cole, Ashley L, Dusetzina, Stacie B

“…The case of generic imatinib demonstrates several potential barriers to effective generic price competition for specialty prescription drugs, including fewer…”
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