Search Results - "COLE, George W"

Valproic Acid, an Antiepileptic Drug with Histone Deacetylase Inhibitory Activity, Potentiates the Cytotoxic Effect of Apo2L/TRAIL on Cultured Thoracic Cancer Cells through Mitochondria-Dependent Caspase Activation by Ziauddin, M. Firdos, Yeow, Wen-Shuz, Maxhimer, Justin B., Baras, Aris, Chua, Alex, Reddy, Rishindra M., Tsai, Wilson, Cole, George W., Schrump, David S., Nguyen, Dao M.

“…Inhibitors of histone deacetylases have been shown to enhance the sensitivity of cancer cells to tumor necrosis factor-related apoptosis-inducing ligand…”
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Suppression of Pro-metastasis Phenotypes Expression in Malignant Pleural Mesothelioma by the PI3K Inhibitor LY294002 or the MEK Inhibitor UO126 by COLE, George W, ALLEVA, Annette M, ZUO, Jing T, SEHGAL, Shailen S, YEOW, Wen-Shuz, SCHRUMP, David S, NGUYEN, Dao M

“…Background: This study aimed to evaluate the impact of selective abrogation of either the MEK/ERK1/2 (UO126 or PD98059) or the PI3K/AKT (LY294002) signaling…”
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The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro by Cole, George W., Alleva, Annette M., Reddy, Rishindra M., Maxhimer, Justin B., Zuo, JingTong, Schrump, David S., Nguyen, Dao M.

“…Malignant pleural mesothelioma is notoriously refractory to aggressive multimodality therapy. Epidermal growth factor receptor expression has been observed on…”
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Induction of apoptosis of lung and esophageal cancer cells treated with the combination of histone deacetylase inhibitor (trichostatin A) and protein kinase C inhibitor (calphostin C) by Maxhimer, Justin B., Reddy, Rishindra M., Zuo, Jingtong, Cole, George W., Schrump, David S., Nguyen, Dao M.

“…Histone deacetylase inhibitors mediate a potent growth-inhibitory effect in cancer cells through induction of cell-cycle arrest and apoptosis. Moreover, these…”
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The essential role of the mitochondria-dependent death-signaling cascade in chemotherapy-induced potentiation of Apo2L/TRAIL cytotoxicity in cultured thoracic cancer cells: amplified caspase 8 is indispensable for combination-mediated massive cell death by Nguyen, Dao M, Yeow, Wen-Shuz, Ziauddin, M Firdos, Baras, Aris, Tsai, Wilson, Reddy, Rishindra M, Chua, Alex, Cole, Jr, George W, Schrump, David S

“…Despite adequately expressing functional receptors for tumor necrosis factor receptor apoptosis-inducing ligand (TRAIL), many cultured tumor cells are…”
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Cisplatin enhances apoptosis induced by a tumor-selective adenovirus expressing tumor necrosis factor-related apoptosis-inducing ligand by Reddy, Rishindra M, Tsai, Wilson S, Ziauddin, M. Firdos, Zuo, JingTong, Cole, George W., Jr, Maxhimer, Justin B, Fang, BingLiang, Schrump, David S, Nguyen, Dao M

“…Cancer cells frequently exhibit resistance to the cytotoxic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Pretreatment of…”
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The leadership principles of Dr. Martin Luther King, Jr. and their relevance to surgery by BRUNICARDI, F. Charles, COTTON, Ronald T, COLE, George W, MARTINEZ, George

“…In order to face the challenges in healthcare this century, it is essential that surgeons understand modern leadership principles. One of the greatest leaders…”
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Cisplatin enhances apoptosis induced by a tumor-selective adenovirus expressing tumor necrosis factor–related apoptosis-inducing ligand by Reddy, Rishindra M., Tsai, Wilson S., Ziauddin, M. Firdos, Zuo, JingTong, Cole, George W., Maxhimer, Justin B., Fang, BingLiang, Schrump, David S., Nguyen, Dao M.

“…Cancer cells frequently exhibit resistance to the cytotoxic effect of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL). Pretreatment of…”
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Interim analysis of ibrutinib plus paclitaxel for patients with advanced urothelial carcinoma previously treated with platinum-based chemotherapy by Castellano, Daniel E., Morales-Barrera, Rafael, Duran, Ignacio, Keam, Bhumsuk, Chung, Ik Joo, Arkenau, Hendrik-Tobias, Vaishampayan, Ulka N., Tuthill, Mark, Gajate, Pablo, Shin, Sang Joon, Dang, S. Paul, Ju, Chia-Hsin, Lin, Jennifer, Cole, George W., James, Danelle Frances, Reig, Oscar

“…Abstract only 4522 Background: Patients (pts) with advanced urothelial carcinoma (aUC) who progressed after platinum-based chemotherapy (PBCT) have a median…”
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A phase 1b/2 study of ibrutinib combination therapy in selected advanced genitourinary and gastrointestinal tumors by Berlin, Jordan, Posadas, Edwin M., Macarulla, Teresa Mercade, Cacovean, Alex, Eckert, Karl, Munneke, Brian, Cole, George W., James, Danelle Frances, Motzer, Robert J.

“…Abstract only…”
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A randomized, double-blind, placebo-controlled study of ibrutinib, a Bruton tyrosine kinase inhibitor, with nab-paclitaxel and gemcitabine in the first-line treatment of patients with metastatic pancreatic adenocarcinoma (RESOLVE) by Tempero, Margaret A., Coussens, Lisa M, Fong, Lawrence, Manges, Robert, Singh, Priyanka, Li, Yunfeng, Cole, George W., James, Danelle Frances, Tabernero, Josep

“…Abstract only…”
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A randomized, multicenter, double-blind, placebo-controlled study of the Bruton tyrosine kinase inhibitor, ibrutinib, versus placebo in combination with nab-paclitaxel and gemcitabine in the first-line treatment of patients with metastatic pancreatic adenocarcinoma (RESOLVE) by Tempero, Margaret A., Coussens, Lisa M, Fong, Lawrence, Manges, Robert, Singh, Priyanka, Li, Yunfeng, Cole, George W., James, Danelle Frances, Tabernero, Josep

“…Abstract only TPS483 Background: Advanced pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor prognosis and short survival…”
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Valproic Acid, an Antiepileptic Drug with Histone Deacetylase Inhibitory Activity, Potentiates the Cytotoxic Effect of Apo2L/TRAIL on Cultured Thoracic Cancer Cells through Mitochondria-Dependent Caspase Activation1 by Ziauddin, M Firdos, Yeow, Wen-Shuz, Maxhimer, Justin B, Baras, Aris, Chua, Alex, Reddy, Rishindra M, Tsai, Wilson, Cole, George W, Schrump, David S, Nguyen, Dao M

“…Inhibitors of histone deacetylases have been shown to enhance the sensitivity of cancer cells to tumor necrosis factor-related apoptosis-inducing ligand…”
Get full text

Cisplatin enhances apoptosis induced by a tumor-selective adenovirus expressing tumor necrosis factor-related apoptosis-inducing ligand. Discussion by REDDY, Rishindra M, TSAI, Wilson S, JONES, David R, ZIAUDDIN, M. Firdos, JINGTONG ZUO, COLE, George W, MAXHIMER, Justin B, BINGLIANG FANG, SCHRUMP, David S, NGUYEN, Dao M, ROTH, Jack

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Induction of apoptosis of lung and esophageal cancer cells treated with the combination of histone deacetylase inhibitor (trichostatin A) and protein kinase C inhibitor (calphostin C). Discussion by MAXHIMER, Justin B, REDDY, Rishindra M, ZUO, Jingtong, COLE, George W, SCHRUMP, David S, NGUYEN, Dao M, D'AMICO, Thomas A, COLSON, Yolonda, BUENO, Raphael

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Iatrogenic transplantation of osteosarcoma by Cole, Jr, G W, Sindelar, W F

“…We report a case in which a patient having curettage and resection of a presumed benign lesion of the tibia (later recognized as osteosarcoma) had probable…”
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At Pompeii and St. Pierre by Cole, George W.

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Hepatitis B antigen and antibody and tests of liver function: a prospective study of 310 hospital laboratory workers by Hirschowitz, B I, Dasher, C A, Whitt, F J, Cole, G W

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COMMITTEE REPORTS, 1923-24 by Craver, Harrison W., Tweedell, Edward D., Meyer, H. H. B., Richardson, Ernest C., Carlton, W. N. C., Keogh, Andrew, Raney, M. Llewellyn, Cannon, Carl L., Wellman, Hiller C., Wright, Purd B., Lydenberg, H. M., Bowerman, George F., Bostwick, Arthur E., Overton, Florence, Ranck, Samuel H., Rathbone, Josephine A., Walter, Frank K., Wyer, Malcolm G., Wood, Harriet A., Avery, Harriet K., Britton, Jasmine, Certain, C. C., Eaton, Anne T., Hazeltine, Alice I., Hull, Edna M., Ingles, May, Lewis, Lucy M., Morgan, Joy E., Pritchard, Martha C., Searson, J. W., Smith, Lillian H., Zachert, Adeline B., Koch, Theodore W., New, Harry S., Wyer, J. I., Barnett, Claribel R., Dudgeon, Matthew S., Thompson, C. S., West, Elizabeth H., Wiley, Edwin, Jones, E. Kathleen, Askew, Sarah B., Bassett, W. S., Emerson, Ralf P., Patterson, J. R., Robinson, Julia A., Templeton, Charlotte, Williams, Nellie, Carey, Miriam E., Yust, William F., Hopper, Franklin F., Goldsmith, Peter H., Sullivan, Maud Durlin, Hicks, Frederick C., Gerould, James Thayer, Butlin, Iva M., Gerould, J. T., Howard, Clara, Kerr, W. H., McCardle, Sarah E., Kaiser, John B., Root, Azariah S., Smith, Bessie Sargeant, Hazeltine, Mary Emogene, Power, Effie L., Dougherty, Harold T., Hughes, Howard L., Johnson, Esther C., Mulheron, Anne M., Reese, Rena, Stewart, Roberta D., Thompson, J. A., Bailey, L. J., Marvin, Cornelia, Reece, Ernest J., Wilson, Louis R., Dickerson, L. L., Shearer, Augustus H., Kobetich, Mary R., Hyde, Dorsey W., Smith, Elizabeth M., Mitchell, Sydney B., Compton, Charles H., Countryman, Gratia A., Lowe, John Adams, Rose, Grace D., Rush, Charles E., Watson, William R., Windsor, P. L., Milam, Carl H., Austen, Willard, Bostwick, A. E., Goldthwaite, Lucille A., Ledbetter, Eleanor E., Farrar, Ida, Gratiaa, Josephine, Hurlbert, Dorothy, Johnson, Esther, Quigley, Margery, Wetmore, Marguerite

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