Search Results - "COLE, Amy L"

Synthesis and bioevaluation of substituted chalcones, coumaranones and other flavonoids as anti-HIV agents by Cole, Amy L., Hossain, Sandra, Cole, Alex M., Phanstiel, Otto

“…[Display omitted] A series of chalcone, flavone, coumaranone and other flavonoid compounds were screened for their anti HIV-1 activity in two cell culture…”
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Identification and characterization of bacterial vaginosis-associated pathogens using a comprehensive cervical-vaginal epithelial coculture assay by Eade, Colleen R, Diaz, Camila, Wood, Matthew P, Anastos, Kathryn, Patterson, Bruce K, Gupta, Phalguni, Cole, Amy L, Cole, Alexander M

“…Bacterial vaginosis (BV) is the most commonly treated female reproductive tract affliction, characterized by the displacement of healthy lactobacilli by an…”
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Reawakening retrocyclins: ancestral human defensins active against HIV-1 by Venkataraman, Nitya, Cole, Amy L, Ruchala, Piotr, Waring, Alan J, Lehrer, Robert I, Stuchlik, Olga, Pohl, Jan, Cole, Alexander M

“…Human alpha and beta defensins contribute substantially to innate immune defenses against microbial and viral infections. Certain nonhuman primates also…”
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HIV-Enhancing and HIV-Inhibiting Properties of Cationic Peptides and Proteins by Cole, Alexander M, Cole, Amy L

“…Cationic antimicrobial peptides and proteins have historically been ascribed roles in innate immunity that infer killing of microbial and viral pathogens and…”
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E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing by Cátala-Valentín, Alma R, Almeda, Jasmine, Bernard, Joshua N, Cole, Alexander M, Cole, Amy L, Moore, Sean D, Andl, Claudia D

“…E-cigarette (e-cig) vapor has been shown to play a pathological role in oral health and alter the oral microbiota, providing growth advantages for…”
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Identification of Nasal Gammaproteobacteria with Potent Activity against Staphylococcus aureus: Novel Insights into the "Noncarrier" State by Cole, Amy L, Sundar, Meera, Lopez, Ana, Forsman, Anna, Yooseph, Shibu, Cole, Alexander M

“…nasal carriage provides the bacterial reservoir for opportunistic infection. In comparing the nasal microbiomes of culture-defined persistent carriers versus…”
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Avirulins, a Novel Class of HIV-1 Reverse Transcriptase Inhibitors Effective in the Female Reproductive Tract Mucosa by Cherne, Michelle D, Hall, Jesse, Kellner, Alisha, Chong, Christine F, Cole, Amy L, Cole, Alexander M

“…While extensive research efforts have decreased human immunodeficiency virus (HIV) transmissions and mortalities, new challenges have arisen in the fight to…”
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Cationic polypeptides contribute to the anti‐HIV‐1 activity of human seminal plasma by Martellini, Julie A., Cole, Amy L., Venkataraman, Nitya, Quinn, Gerry A., Svoboda, Pavel, Gangrade, Bhushan K, Pohl, Jan, Sørensen, Ole E., Cole, Alexander M.

“…ABSTRACT Mucosal surfaces of the reproductive tract as well as their secretions have important roles in preventing sexual transmission of HIV‐1. In the current…”
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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques by Cole, Alexander M, Patton, Dorothy L, Rohan, Lisa C, Cole, Amy L, Cosgrove-Sweeney, Yvonne, Rogers, Nicole A, Ratner, Deena, Sassi, Alexandra B, Lackman-Smith, Carol, Tarwater, Patrick, Ramratnam, Bharat, Ruchala, Piotr, Lehrer, Robert I, Waring, Alan J, Gupta, Phalguni

“…RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major…”
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HIV-neutralizing activity of cationic polypeptides in cervicovaginal secretions of women in HIV-serodiscordant relationships by Levinson, Pauline, Choi, Robert Y, Cole, Amy L, Hirbod, Taha, Rhedin, Samuel, Payne, Barbara, Guthrie, Brandon L, Bosire, Rose, Cole, Alexander M, Farquhar, Carey, Broliden, Kristina

“…HIV exposed seronegative (HESN) women represent the population most in need of a prophylactic antiviral strategy. Mucosal cationic polypeptides can potentially…”
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Morphology-Dependent HIV-Enhancing Effect of Semen-Derived Enhancer of Viral Infection by Qiao, Xin, Jeon, Jaekyun, Cole, Amy L., Matos, Jason O., Bautista, Stephany, Castillo, Justin, Hung, Ivan, Gan, Zhehong, Tatulian, Suren A., Cole, Alexander M., Chen, Bo

“…PAP248–286 is a 39-residue fragment (residues 248 to 286) derived from protease cleavage of prostatic acidic phosphatase in semen. The amyloid fibrils formed…”
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HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma by Martellini, Julie A, Cole, Amy L, Svoboda, Pavel, Stuchlik, Olga, Chen, Li-Mei, Chai, Karl X, Gangrade, Bhushan K, Sørensen, Ole E, Pohl, Jan, Cole, Alexander M

“…We recently reported that HIV-1 infection can be inhibited by innate antimicrobial components of human seminal plasma (SP). Conversely, naturally occurring…”
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Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers by Birse, Kenzie D M, Cole, Amy L, Hirbod, Taha, McKinnon, Lyle, Ball, Terry B, Westmacott, Garrett R, Kimani, Joshua, Plummer, Frank, Cole, Alexander M, Burgener, Adam, Broliden, Kristina

“…Cationic proteins found in cervicovaginal secretions (CVS) are known to contribute to the early antiviral immune response against HIV-infection in vitro. We…”
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Oxidized Phospholipid-Induced Endothelial Cell/Monocyte Interaction Is Mediated by a cAMP-Dependent R-Ras/PI3-Kinase Pathway by Cole, Amy L, Subbanagounder, Ganesamoorthy, Mukhopadhyay, Srirupa, Berliner, Judith A, Vora, Devendra K

“…OBJECTIVE—Previous studies have demonstrated the importance of endothelial apical expression of connecting segment-1 (CS-1) fibronectin in mediating the entry…”
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Specific Phospholipid Oxidation Products Inhibit Ligand Activation of Toll-Like Receptors 4 and 2 by Walton, Kimberly A, Cole, Amy L, Yeh, Michael, Subbanagounder, Ganesamoorthy, Krutzik, Stephan R, Modlin, Robert L, Lucas, Robert M, Nakai, Junko, Smart, Eric J, Vora, Deven K, Berliner, Judith A

“…OBJECTIVE—We have previously shown that phospholipid oxidation products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (ox-PAPC) inhibit…”
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Characterization of the Retrocyclin Analogue RC-101 as a Preventative of Staphylococcus aureus Nasal Colonization by LAMERS, Ryan P, EADE, Colleen R, WARING, Alan J, COLE, Amy L, COLE, Alexander M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion by Wood, Matthew P, Cole, Amy L, Ruchala, Piotr, Waring, Alan J, Rohan, Lisa C, Marx, Preston, Tarwater, Patrick M, Gupta, Phalguni, Cole, Alexander M

“…Fusion inhibitors are a class of antiretroviral drugs used to prevent entry of HIV into host cells. Many of the fusion inhibitors being developed, including…”
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Correction: Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers by Birse, Kenzie D M, Cole, Amy L, Hirbod, Taha, McKinnon, Lyle, Ball, Terry B, Westmacott, Garrett R, Kimani, Joshua, Plummer, Frank, Cole, Alexander M, Burgener, Adam, Broliden, Kristina

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Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin by Micewicz, Ewa D, Cole, Amy L, Jung, Chun-Ling, Luong, Hai, Phillips, Martin L, Pratikhya, Pratikhya, Sharma, Shantanu, Waring, Alan J, Cole, Alexander M, Ruchala, Piotr

“…Griffithsin, a 121-residue protein isolated from a red algal Griffithsia sp., binds high mannose N-linked glycans of virus surface glycoproteins with extremely…”
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Oxidized Phospholipids Increase Interleukin 8 (IL-8) Synthesis by Activation of the c-src/Signal Transducers and Activators of Transcription (STAT)3 Pathway by Yeh, Michael, Gharavi, Nima M, Choi, Jenny, Hsieh, Xavier, Reed, Erin, Mouillesseaux, Kevin P, Cole, Amy L, Reddy, Srinivasa T, Berliner, Judith A

“…Oxidized 1-palmitoyl-2-arachidonoyl- sn -glycero-3-phosphorylcholine (Ox-PAPC) and its component phospholipids 1-palmitoyl-2-epoxyisoprostane- sn…”
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