Search Results - "COLANTONIO, David"
-
1
Closing the Gaps in Pediatric Laboratory Reference Intervals: A CALIPER Database of 40 Biochemical Markers in a Healthy and Multiethnic Population of Children
Published in Clinical chemistry (Baltimore, Md.) (01-05-2012)“…Pediatric healthcare is critically dependent on the availability of accurate and precise laboratory biomarkers of pediatric disease, and on the availability of…”
Get full text
Journal Article -
2
Marked biological variance in endocrine and biochemical markers in childhood: establishment of pediatric reference intervals using healthy community children from the CALIPER cohort
Published in Clinical chemistry (Baltimore, Md.) (01-09-2013)“…Reference intervals are indispensable in evaluating laboratory test results; however, appropriately partitioned pediatric reference values are not readily…”
Get full text
Journal Article -
3
New Psychoactive Substances: A Canadian perspective on emerging trends and challenges for the clinical laboratory
Published in Clinical biochemistry (01-12-2024)“…•New Psychoactive Substances (NPS) are referred to as “legal highs”, due to their constantly evolving structures allowing them to temporarily bypass…”
Get full text
Journal Article -
4
Canadian guidance for diagnosis and management of acute hepatic porphyrias
Published in Clinical biochemistry (01-10-2024)“…•AHP results from abnormal heme biosynthesis causing neurological symptoms during acute attacks.•Various triggers stimulate heme synthesis, elevate heme…”
Get full text
Journal Article -
5
Predicting Escitalopram Exposure to Breastfeeding Infants: Integrating Analytical and In Silico Techniques
Published in Clinical pharmacokinetics (01-12-2018)“…Background Escitalopram is used for post-partum depression; however, there are limited pharmacokinetic data of escitalopram in milk and plasma of infants…”
Get full text
Journal Article -
6
Validity of establishing pediatric reference intervals based on hospital patient data: A comparison of the modified Hoffmann approach to CALIPER reference intervals obtained in healthy children
Published in Clinical biochemistry (01-02-2014)“…To compare pediatric reference intervals calculated using hospital-based patient data with those calculated using samples collected from healthy children in…”
Get full text
Journal Article -
7
Milrinone therapeutic drug monitoring in a pediatric population: Development and validation of a quantitative liquid chromatography-tandem mass spectrometry method
Published in Clinica chimica acta (01-05-2017)“…Milrinone is a potent selective phosphodiesterase type III inhibitor which stimulates myocardial function and improves myocardial relaxation. Although…”
Get full text
Journal Article -
8
Pediatric within-day biological variation and quality specifications for 38 biochemical markers in the CALIPER cohort
Published in Clinical chemistry (Baltimore, Md.) (01-03-2014)“…Studies of biological variation provide insight into the physiological changes that occur within and between study participants. Values obtained from such…”
Get full text
Journal Article -
9
CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: Direct validation using reference samples from the CALIPER cohort
Published in Clinical biochemistry (01-09-2013)“…The CALIPER program recently established a comprehensive database of age- and sex-stratified pediatric reference intervals for 40 biochemical markers. However,…”
Get full text
Journal Article -
10
Evaluation of electrochemiluminescence immunoassays for immunosuppressive drugs on the Roche cobas e411 analyzer
Published in F1000 research (2017)“…Background : Therapeutic drug monitoring of immunosuppressant drugs are used to monitor drug efficacy and toxicity and to prevent organ transplant rejection…”
Get full text
Journal Article -
11
Pediatric reference intervals for 28 chemistries and immunoassays on the Roche cobas® 6000 analyzer—A CALIPER pilot study
Published in Clinical biochemistry (01-09-2010)“…The aim of this study was to determine age- and sex-specific pediatric reference intervals for 28 analytes on the Roche cobas ® 6000 analyzer. The study was…”
Get full text
Journal Article -
12
Effective interventions to improve the quality of critically high point-of-care glucose meter results
Published in Practical laboratory medicine (01-11-2020)“…Point-of-care testing (POCT) is testing performed outside the traditional laboratory, often at the patient bedside. In hospital settings, blood glucose is the…”
Get full text
Journal Article -
13
Effective removal of albumin from serum
Published in Proteomics (Weinheim) (01-10-2005)“…The protein constituents of serum can range from grams to picograms per liter, making it technically difficult to achieve in‐depth proteomic analysis. Removal…”
Get full text
Journal Article -
14
The clinical application of proteomics
Published in Clinica chimica acta (24-07-2005)“…Proteomics is defined as a scientific approach used to elucidate all protein species within a cell or tissue, and many researchers are taking advantage of…”
Get full text
Journal Article -
15
Implications of serum creatinine measurements on GFR estimation and vancomycin dosing in children
Published in Journal of clinical pharmacology (01-07-2014)“…Background Different serum creatinine (sCr) assays may obtain different values in the same patient, causing discrepancies in estimated glomerular filtration…”
Get full text
Journal Article -
16
Evaluation of electrochemiluminescence immunoassays for immunosuppressive drugs on the Roche cobas e411 analyzer [version 1; peer review: 2 approved]
Published in F1000 research (2017)“…Background: Therapeutic drug monitoring of immunosuppressant drugs are used to monitor drug efficacy and toxicity and to prevent organ transplantation…”
Get full text
Journal Article -
17
Comparison of the CEDIA® and MEIA® assays for the measurement of sirolimus in organ transplant recipients
Published in Clinical biochemistry (01-06-2007)“…This study evaluated two immunoassays, the CEDIA® assay and the MEIA® assay, used for the measurement of whole blood levels of sirolimus in organ transplant…”
Get full text
Journal Article -
18
Stunned peri-infarct canine myocardium is characterized by degradation of troponin T, not troponin I
Published in Cardiovascular research (01-08-2004)“…Degradation of cardiac troponin I (cTnI) has been proposed to represent the underlying molecular mechanism responsible for post-ischemic contractile…”
Get full text
Journal Article -
19
-
20
Broad spectrum urine drug screening: The challenges of assessing qualitative cut-off performance characteristics in an LC–MS/MS System
Published in Clinical biochemistry (01-10-2015)Get full text
Journal Article