Search Results - "COHEN, Noah D."

Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease by Rossi, Giacomo, Pengo, Graziano, Caldin, Marco, Palumbo Piccionello, Angela, Steiner, Jörg M, Cohen, Noah D, Jergens, Albert E, Suchodolski, Jan S

“…Idiopathic inflammatory bowel disease (IBD) is a common chronic enteropathy in dogs. There are no published studies regarding the use of probiotics in the…”
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Comparison of the microbiome, metabolome, and lipidome of obese and non-obese horses by Coleman, Michelle C, Whitfield-Cargile, Canaan M, Madrigal, Rodolfo G, Cohen, Noah D

“…Metabolic diseases such as obesity and type 2 diabetes in humans have been linked to alterations in the gastrointestinal microbiota and metabolome. Knowledge…”
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Rhodococcus equi foal pneumonia: Update on epidemiology, immunity, treatment and prevention by Bordin, Angela I., Huber, Laura, Sanz, Macarena G., Cohen, Noah D.

“…Pneumonia in foals caused by the bacterium Rhodococcus equi has a worldwide distribution and is a common cause of disease and death for foals. The purpose of…”
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Feasibility of a point‐of‐care ultrasound protocol for cardiorespiratory evaluation of horses in different clinical settings by Bevevino, Kari E., Cohen, Noah D., Gordon, Sonya G., Navas de Solis, Cristobal

“…Background A point‐of‐care ultrasound (POCUS) protocol for evaluation of the cardiac and respiratory systems in horses does not exist. Objectives (a) Describe…”
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Differential effects of selective and non-selective cyclooxygenase inhibitors on fecal microbiota in adult horses by Whitfield-Cargile, Canaan M, Chamoun-Emanuelli, Ana M, Cohen, Noah D, Richardson, Lauren M, Ajami, Nadim J, Dockery, Hannah J

“…Non-steroidal anti-inflammatory drugs (NSAIDs) are routinely used in both veterinary and human medicine. Gastrointestinal injury is a frequent adverse event…”
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The novel and transferable erm(51) gene confers macrolides, lincosamides and streptogramins B (MLSB) resistance to clonal Rhodococcus equi in the environment by Huber, Laura, Giguère, Steeve, Slovis, Nathan M., Álvarez‐Narváez, Sonsiray, Hart, Kelsey A., Greiter, Maggie, Morris, Ellen Ruth A., Cohen, Noah D.

“…Summary The use of mass antimicrobial treatment has been linked to the emergence of antimicrobial resistance in human and animal pathogens. Using whole‐genome…”
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Correction: Detection of vapN in Rhodococcus equi isolates cultured from humans by Bryan, Laura K, Alexander, Ellen Ruth, Lawhon, Sara D, Cohen, Noah D

“…[This corrects the article DOI: 10.1371/journal.pone.0190829.]…”
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Conservation of vaccine antigen sequences encoded by sequenced strains of Streptococcus equi subsp. equi by Frosth, Sara, Morris, Ellen Ruth A., Wilson, Hayley, Frykberg, Lars, Jacobsson, Karin, Parkhill, Julian, Flock, Jan‐Ingmar, Wood, Tim, Guss, Bengt, Aanensen, David M., Boyle, Ashley G., Riihimäki, Miia, Cohen, Noah D., Waller, Andrew S.

“…Summary Background Streptococcus equi subspecies equi (S equi) is the cause of Strangles, one of the most prevalent diseases of horses worldwide. Variation…”
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Detection of vapN in Rhodococcus equi isolates cultured from humans by Bryan, Laura K, Alexander, Ellen Ruth, Lawhon, Sara D, Cohen, Noah D

“…Rhodococcus equi can cause severe infections in people, particularly in immunocompromised individuals. The R. equi virulence plasmids (vap) encoding vapA and…”
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The microbiota-derived metabolite indole decreases mucosal inflammation and injury in a murine model of NSAID enteropathy by Whitfield-Cargile, Canaan M., Cohen, Noah D., Chapkin, Robert S., Weeks, Brad R., Davidson, Laurie A., Goldsby, Jennifer S., Hunt, Carrie L., Steinmeyer, Shelby H., Menon, Rani, Suchodolski, Jan S., Jayaraman, Arul, Alaniz, Robert C.

“…Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently used classes of medications in the world. Unfortunately, NSAIDs induce an…”
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Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia by Bordin, Angela I., Cohen, Noah D., Giguère, Steve, Bray, Jocelyne M., Berghaus, Londa J., Scott, Brenton, Johnson, Rena, Hook, Magnus

“…Pneumonia caused by the intracellular bacterium Rhodococcus equi is an important cause of disease and death in immunocompromised hosts, especially foals…”
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Assessment of microbiological correlates and immunostimulatory potential of electron beam inactivated metabolically active yet non culturable (MAyNC) Salmonella Typhimurium by Praveen, Chandni, Bhatia, Sohini S, Alaniz, Robert C, Droleskey, Robert E, Cohen, Noah D, Jesudhasan, Palmy R, Pillai, Suresh D

“…This study investigates the microbiological and immunological basis underlying the efficacy of electron beam-inactivated immune modulators. The underlying…”
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Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi by Cywes-Bentley, Colette, Rocha, Joana N, Bordin, Angela I, Vinacur, Mariana, Rehman, Safia, Zaidi, Tanweer S, Meyer, Mark, Anthony, Sarah, Lambert, McKenzie, Vlock, Daniel R, Giguère, Steeve, Cohen, Noah D, Pier, Gerald B

“…Immune correlates of protection against intracellular bacterial pathogens are largely thought to be cell-mediated, although a reasonable amount of data…”
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Macrolide- and rifampin-resistant Rhodococcus equi on a horse breeding farm, Kentucky, USA by Burton, Alexandra J, Giguère, Steeve, Sturgill, Tracy L, Berghaus, Londa J, Slovis, Nathan M, Whitman, Jeremy L, Levering, Court, Kuskie, Kyle R, Cohen, Noah D

“…Macrolide and rifampin resistance developed on a horse breeding farm after widespread use was instituted for treatment of subclinical pulmonary lesions in…”
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Differences in the genome, methylome, and transcriptome do not differentiate isolates of Streptococcus equi subsp. equi from horses with acute clinical signs from isolates of inapparent carriers by Morris, Ellen Ruth A, Boyle, Ashley G, Riihimäki, Miia, Aspán, Anna, Anis, Eman, Hillhouse, Andrew E, Ivanov, Ivan, Bordin, Angela I, Pringle, John, Cohen, Noah D

“…Streptococcus equi subsp. equi (SEE) is a host-restricted bacterium that causes the common infectious upper respiratory disease known as strangles in horses…”
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Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent by Legere, Rebecca M., Cohen, Noah D., Poveda, Cristina, Bray, Jocelyne M., Barhoumi, Rola, Szule, Joseph A., de la Concha-Bermejillo, Andrés, Bordin, Angela I., Pollet, Jeroen

“…Vaccines and therapeutics using in vitro transcribed mRNA hold enormous potential for human and veterinary medicine. Transfection agents are widely considered…”
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Vaccination of yearling horses against poly-N-acetyl glucosamine fails to protect against infection with Streptococcus equi subspecies equi by Cohen, Noah D, Cywes-Bentley, Colette, Kahn, Susanne M, Bordin, Angela I, Bray, Jocelyne M, Wehmeyer, S Garrett, Pier, Gerald B

“…Strangles is a common disease of horses with worldwide distribution caused by the bacterium Streptococcus equi subspecies equi (SEE). Although vaccines against…”
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Whole-genome sequencing and genetic variant analysis of a Quarter Horse mare by Doan, Ryan, Cohen, Noah D, Sawyer, Jason, Ghaffari, Noushin, Johnson, Charlie D, Dindot, Scott V

“…The catalog of genetic variants in the horse genome originates from a few select animals, the majority originating from the Thoroughbred mare used for the…”
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The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages by Vail, Krystal J, da Silveira, Bibiana Petri, Bell, Samantha L, Cohen, Noah D, Bordin, Angela I, Patrick, Kristin L, Watson, Robert O

“…Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the…”
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Opsonization but not pretreatment of equine macrophages with hyperimmune plasma nonspecifically enhances phagocytosis and intracellular killing of Rhodococcus equi by Harvey, Aja B., Bordin, Angela I., Rocha, Joana N., Bray, Jocelyn M., Cohen, Noah D.

“…Background Evidence regarding the efficacy of equine hyperimmune plasma to prevent pneumonia in foals caused by Rhodococcus equi is limited and conflicting…”
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