Search Results - "COFFEY, T"
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Microtubule and microtubule associated protein anomalies in psychiatric disease
Published in Cytoskeleton (Hoboken, N.J.) (01-10-2016)“…Anomalies in neuronal cell architecture, in particular dendritic complexity and synaptic density changes, are widely observed in the brains of subjects with…”
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Repositioning Microtubule Stabilizing Drugs for Brain Disorders
Published in Frontiers in cellular neuroscience (08-08-2018)“…Microtubule stabilizing agents are among the most clinically useful chemotherapeutic drugs. Mostly, they act to stabilize microtubules and inhibit cell…”
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3
Monitoring biodiversity loss in rapidly changing Afrotropical ecosystems: an emerging imperative for governance and research
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (17-07-2023)“…Africa is experiencing extensive biodiversity loss due to rapid changes in the environment, where natural resources constitute the main instrument for…”
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Considerations for environmental biogeochemistry and food security for aquaculture around Lake Victoria, Kenya
Published in Environmental geochemistry and health (01-08-2023)“…The impact of population expansion through economic growth and development has been identified as one of the key drivers of both water and sediment…”
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Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
Published in Journal of Virology (01-02-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
Assessing the spatial distribution of elemental concentrations in surface sediments of Lake Victoria, Kenya: implications for ecological health and management
Published in Environmental geochemistry and health (01-04-2024)“…Lacustrine sediment quality indicates the effects of both natural and anthropogenic activities on the ecosystem and communities. Despite its ecological…”
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Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes
Published in Cancer research (Chicago, Ill.) (01-12-2015)“…The anticancer properties of cruciferous vegetables are well known and attributed to an abundance of isothiocyanates such as benzyl isothiocyanate (BITC) and…”
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8
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin
Published in Nature neuroscience (01-07-2009)“…PolyQ-Htt inhibits fast axonal transport in cellular and animal Huntington's disease models. Here, the authors show that this effect is a result of the…”
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Genomic heterogeneity of Dichelobacter nodosus within and between UK sheep flocks and between age groups within a flock
Published in BMC microbiology (01-05-2020)“…Footrot and interdigital dermatitis are endemic infectious diseases in all sheep farming regions, impairing welfare and production. The development of…”
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Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate
Published in Nature neuroscience (01-03-2011)“…Westerlund and colleagues show that c-Jun N-terminal protein kinase 1 (JNK1), via phosphorylation of SCG10/Stathmin-2, acts as a negative regulator of the rate…”
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Nuclear and cytosolic JNK signalling in neurons
Published in Nature reviews. Neuroscience (01-05-2014)“…Key Points JUN amino-terminal kinases (JNKs) are dominant regulators of protein phosphorylation in the nervous system. JNKs serve critical functions in…”
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c-Jun N-Terminal Kinase Phosphorylation of MARCKSL1 Determines Actin Stability and Migration in Neurons and in Cancer Cells
Published in Molecular and Cellular Biology (01-09-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Recent Northern Hemisphere stratospheric HCl increase due to atmospheric circulation changes
Published in Nature (London) (06-11-2014)“…Policies have been in place since 1987 to reduce the release of chlorine atoms in the stratosphere, where they deplete ozone; here observations show that since…”
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Microtubule Stabilization by Bone Morphogenetic Protein Receptor-Mediated Scaffolding of c-Jun N-Terminal Kinase Promotes Dendrite Formation
Published in Molecular and Cellular Biology (01-05-2010)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
LRRfinder: A web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database
Published in Developmental and comparative immunology (01-10-2010)“…Homology modelling is considered the most accurate technique for computational prediction of protein structure. However, this technique comes with fundamental…”
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PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins
Published in Cell communication and signaling (08-08-2020)“…The PIM family kinases promote cancer cell survival and motility as well as metastatic growth in various types of cancer. We have previously identified several…”
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Cattle and chemokines: evidence for species-specific evolution of the bovine chemokine system
Published in Animal genetics (01-08-2011)“…Summary The chemokine system comprises a family of small chemoattractant molecules that have roles in both the healthy and diseased organism. Chemokines act by…”
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JNK1 Phosphorylation of SCG10 Determines Microtubule Dynamics and Axodendritic Length
Published in The Journal of cell biology (24-04-2006)“…C-Jun NH2-terminal kinases (JNKs) are essential during brain development, when they regulate morphogenic changes involving cell movement and migration. In the…”
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Analysis of ozone and nitric acid in spring and summer Arctic pollution using aircraft, ground-based, satellite observations and MOZART-4 model: source attribution and partitioning
Published in Atmospheric chemistry and physics (04-01-2012)“…In this paper, we analyze tropospheric O3 together with HNO3 during the POLARCAT (Polar Study using Aircraft, Remote Sensing, Surface Measurements and Models,…”
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Lithium Blocks the c-Jun Stress Response and Protects Neurons via Its Action on Glycogen Synthase Kinase 3
Published in Molecular and Cellular Biology (01-09-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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