Search Results - "COFFEE, Richard"

Non-invasive detection of a small number of bioluminescent cancer cells in vivo by Kim, Jae-Beom, Urban, Konnie, Cochran, Edward, Lee, Steve, Ang, Angel, Rice, Bradley, Bata, Adam, Campbell, Kenneth, Coffee, Richard, Gorodinsky, Alex, Lu, Zhan, Zhou, He, Kishimoto, Takashi Kei, Lassota, Peter

“…Early detection of tumors can significantly improve the outcome of tumor treatment. One of the most frequently asked questions in cancer imaging is how many…”
Get full text

Noninvasive bioluminescence imaging of normal and spontaneously transformed prostate tissue in mice by LYONS, Scott K, LIM, Ed, JENKINS, Darlene, CLERMONT, Anne O, DUSICH, Joan, LINGYUN ZHU, CAMPBELL, Kenneth D, COFFEE, Richard J, GRASS, David S, HUNTER, John, PURCHIO, Tony

“…Several transgenic mouse models of prostate cancer have been developed recently that are able to recapitulate many key biological features of the human…”
Get full text

A TRANSGENIC MOUSE MODEL WITH A LUCIFERASE REPORTER FOR STUDYING IN VIVO TRANSCRIPTIONAL REGULATION OF THE HUMAN CYP3A4 GENE by WEISHENG ZHANG, PURCHIO, Anthony F, CHEN, Kevin, JIANMING WU, LI LU, COFFEE, Richard, CONTAG, Pamela R, WEST, David B

“…Cytochrome P450 3A4 (CYP3A4) plays an important role in drug metabolism, and the enzymatic activity of CYP3A4 contributes to many adverse drug-drug…”
Get full text

DIFFERENTIAL REGULATION OF THE HUMAN CYP3A4 PROMOTER IN TRANSGENIC MICE AND RATS by WEISHENG ZHANG, PURCHIO, Anthony F, COFFEE, Richard, WEST, David B

“…Previously we described a transgenic mouse model [FVB/NTg( CYP3A4-luc )Xen] using a reporter construct consisting of 13 kilobases of the human CYP3A4 promoter…”
Get full text

Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters by Jiang, Weiwu, Wang, Lihua, Zhang, Weisheng, Coffee, Richard, Fazili, Inayat S., Moorthy, Bhagavatula

“…There is significant human exposure to polycyclic aromatic hydrocarbons (PAHs), many of which are potent carcinogens. Cytochrome P450 (CYP)1A enzymes play key…”
Get full text

A Cyp1a2-Luciferase Transgenic CD-1 Mouse Model: Responses to Aryl Hydrocarbons Similar to the Humanized AhR Mice by Zhang, Weisheng, Moorthy, Bhagavatula, Chen, Min, Muthiah, Kathirvel, Coffee, Richard, Purchio, Anthony F., West, David B.

“…Here we describe a transgenic mouse model [Crl:CD-1(ICR)BR-Tg(Cyp1a2-luc)Xen] using luciferase as a reporter for Cyp1a2 gene regulation. An 8.4-kilobase mouse…”
Get full text

Somatic Recombination of Heavy Chain Variable Region Transgenes with the Endogenous Immunoglobulin Heavy Chain Locus in Mice by Giusti, Angela M., Coffee, Richard, Manser, Tim

“…Transgenic lines of mice were derived by using plasmid constructs containing DNA encoding an antibody heavy chain variable-diversity-joining region (VH-D-JH)…”
Get full text

Missa "Sunt bona mixta malis" by Coffee, Richard

Get full text

COMPLEX: an Applesoft BASIC program to assess preference for visual complexity by DENI, R, COFFEE, R. J

Get full text