Search Results - "COECKELBERGHS, M"

In antibody-positive first-degree relatives of patients with type 1 diabetes, HLA-A24 and HLA-B18, but not HLA-B39, are predictors of impending diabetes with distinct HLA-DQ interactions by Mbunwe, E., Van der Auwera, B. J., Weets, I., Van Crombrugge, P., Crenier, L., Coeckelberghs, M., Seret, N., Decochez, K., Vandemeulebroucke, E., Gillard, P., Keymeulen, B., van Schravendijk, C., Wenzlau, J. M., Hutton, J. C., Pipeleers, D. G., Gorus, F. K.

“…Aims/hypothesis Secondary type 1 diabetes prevention trials require selection of participants with impending diabetes. HLA-A and - B alleles have been reported…”
Get full text

Care delivery and outcomes among Belgian children and adolescents with type 1 diabetes by Doggen, K., Debacker, N., Beckers, D., Casteels, K., Coeckelberghs, M., Dooms, L., Dorchy, H., Lebrethon, M., Logghe, K., Maes, M., Massa, G., Mouraux, T., Rooman, R., Thiry-Counson, G., Van Aken, S., Vanbesien, J., Van Casteren, V.

“…We aimed to investigate care processes and outcomes among children and adolescents with type 1 diabetes treated in hospital-based multidisciplinary paediatric…”
Get full text

The age at diagnosis of type 1 diabetes continues to decrease in Belgian boys but not in girls: a 15-year survey by Weets, I., Rooman, R., Coeckelberghs, M., De Block, C., Van Gaal, L., Kaufman, J.-M., Keymeulen, B., Mathieu, C., Weber, E., Pipeleers, D. G., Gorus, F. K.

“…Background The age at clinical onset of type 1 diabetes is decreasing. Preliminary Belgian data suggested that this anticipation occurred preferentially in…”
Get full text

Seasonality in clinical onset of Type 1 diabetes in Belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence by WEETS, I, KAUFMAN, L, PIPELEERS, D. G, GORUS, F. K, VAN DER AUWERA, B, CRENIER, L, ROOMAN, R. P. A, DE BLOCK, C, CASTEELS, K, WEBER, E, COECKELBERGHS, M, LARON, Z

“…Type 1 diabetes arises from an interplay between environmental and genetic factors. The reported seasonality at diagnosis supports the hypothesis that…”
Get full text

Epidemiology, clinical aspects, and biology of iddm patients under age 40 years : Comparison of data from Antwerp with complete ascertainment with data from Belgium with 40% ascertainment by VANDEWALLE, C. L, COECKELBERGHS, M. I, DE LEEUW, I. H, DU CAJU, M. V, SCHUIT, F. C, PIPELEERS, D. G, GORUS, F. K

Get full text

Incidence and trends of childhood Type 1 diabetes worldwide 1990-1999

“…Aims  To examine incidence and trends of Type 1 diabetes worldwide for the period 1990–1999. Methods  The incidence of Type 1 diabetes (per 100 000/year) was…”
Get full text

CTLA‐4 gene polymorphism confers susceptibility to insulin‐dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers by VAN DER AUWERA, B. J., VANDEWALLE, C. L., SCHUIT, F. C., WINNOCK, F., DE LEEUW, I. H., VAN IMSCHOOT, S., LAMBERIGTS, G., GORUS, F. K.

“…Apart from genes in the HLA complex (IDDM1) and the variable number of tandem repeats in the 5′ region of the insulin gene (INS VNTR, IDDM2), several other…”
Get full text

Epidemiology, clinical aspects, and biology of IDDM patients under age 40 years. Comparison of data from Antwerp with complete ascertainment with data from Belgium with 40% ascertainment. The Belgian Diabetes Registry by Vandewalle, C L, Coeckelberghs, M I, De Leeuw, I H, Du Caju, M V, Schuit, F C, Pipeleers, D G, Gorus, F K

“…Epidemiology, clinical aspects, and biology of IDDM patients under age 40 years. Comparison of data from Antwerp with complete ascertainment with data from…”
Get full text

IA-2 autoantibodies predict impending Type I diabetes in siblings of patients by DECOCHEZ, K, DE LEEUW, I. H, PIPELEERS, D. G, GORUS, F. K, KEYMEULEN, B, MATHIEU, C, ROTTIERS, R, WEETS, I, VANDEMEULEBROUCKE, E, TRUYEN, I, KAUFMAN, L, SCHUIT, F. C

“…Multiple islet autoantibody positivity is currently believed to best predict progression to Type I (insulin-dependent) diabetes mellitus. We compared its…”
Get full text

Associations of GAD65- and IA-2-autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings by VANDEWALLE, C. L, FALORNI, A, PIPELEERS, D. G, GORUS, F. K, LERNMARK, A, GOUBERT, P, DORCHY, H, COUCKE, W, SEMAKULA, C, VAN DER AUWERA, B, KAUFMAN, L, SCHUIT, F. C

“…To investigate the association of GAD (65-kDa) autoantibodies (GAD65-Abs) and IA-2 autoantibodies (IA-2-Abs) with human leukocyte antigen (HLA)-DQ and insulin…”
Get full text

P29 Age- and gender-specific differences in incidence rates of type 1 diabetes in Antwerp, Belgium (1989–1997) by Weets, I., Dorchy, H., Coeckelberghs, M., De Leeuw, I., Du Caju, M., Decochez, K., Vandewalle, C., Gorus, F., Belgian Diabetes Registry

Get full text

Abnormal circulating pancreatic enzyme activities in more than twenty-five percent of recent-onset insulin-dependent diabetic patients: association of hyperlipasemia with high-titer islet cell antibodies. Belgian Diabetes Registry by Semakula, C, Vandewalle, C L, Van Schravendijk, C F, Sodoyez, J C, Schuit, F C, Foriers, A, Falorni, A, Craen, M, Decraene, P, Pipeleers, D G, Gorus, F K

“…Pancreatic amylase and lipase activities were measured in sera of 307 Caucasian insulin-dependent diabetes mellitus patients (IDDM) at clinical onset, 303…”
Get full text

Severe liver damage following administration of valproic acid (Depakine) by Coeckelberghs, M, van Caillie-Bertrand, M, Bultinck, J, Clara, R

Get more information