Search Results - "COCKCROFT, J. R"

Randomized clinical trial of angiotensin-converting enzyme inhibitor, ramipril, in patients with intermittent claudication by Shahin, Y., Cockcroft, J. R., Chetter, I. C.

“…Background The aim was to investigate the effect of ramipril on clinical parameters in patients with peripheral arterial disease. Methods Patients with…”
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Increased augmentation index in patients with cystic fibrosis by Hull, J. H, Garrod, R, Ho, T. B, Knight, R. K, Cockcroft, J. R, Shale, D. J, Bolton, C. E

“…Increased large artery stiffness occurs in a range of inflammatory conditions indicating an ageing of the vasculature and additionally being an independent…”
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Arterial stiffness and central blood pressure, as determined by pulse wave analysis, in rheumatoid arthritis by Klocke, R, Cockcroft, J R, Taylor, G J, Hall, I R, Blake, D R

“…Background: Rheumatoid arthritis (RA) is associated with increased cardiovascular mortality for reasons which are insufficiently understood. Chronic…”
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Assessment of arterial stiffness in clinical practice by Mackenzie, I.S., Wilkinson, I.B., Cockcroft, J.R.

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The effect of exercise on large artery haemodynamics in healthy young men by Sharman, J. E., McEniery, C. M., Campbell, R. I., Coombes, J. S., Wilkinson, I. B., Cockcroft, J. R.

“…Background  Brachial blood pressure predicts cardiovascular outcome at rest and during exercise. However, because of pulse pressure amplification, there is a…”
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Effects of GH replacement on endothelial function and large-artery stiffness in GH-deficient adults: a randomized, double-blind, placebo-controlled study by Smith, J. C., Evans, L. M., Wilkinson, I., Goodfellow, J., Cockcroft, J. R., Scanlon, M. F., Davies, J. S.

“…Summary objectives Hypopituitary adults with growth hormone deficiency (GHD) have an increased cardiovascular mortality, although the mechanisms remain…”
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Nebivolol vasodilates human forearm vasculature: evidence for an L-arginine/NO-dependent mechanism by Cockcroft, J R, Chowienczyk, P J, Brett, S E, Chen, C P, Dupont, A G, Van Nueten, L, Wooding, S J, Ritter, J M

“…Nebivolol, a beta 1 selective adrenergic receptor antagonist with additional properties, is a racemic mixture of (S,R,R,R)- and (R,S,S,S)-enantiomers. We…”
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Effect of oral vitamin E (α-tocopherol) supplementation on vascular endothelial function in Type 2 diabetes mellitus by Gazis, A., White, D. J., Page, S. R., Cockcroft, J. R.

“…Summary Aims Vascular endothelial dysfunction, an early marker of atherosclerosis, has been demonstrated in Type 2 diabetes mellitus (DM). Vitamin E preserves…”
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Left ventricular mechanics in late second trimester of healthy pregnancy by Meah, V. L., Backx, K., Cockcroft, J. R., Shave, R. E., Stöhr, E. J.

“…ABSTRACT Objective To evaluate left ventricular (LV) mechanics in the second trimester of healthy pregnancy and to determine the influence of underpinning…”
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Is arterial stiffening in Alström syndrome linked to the development of cardiomyopathy? by Smith, J. C., McDonnell, B., Retallick, C., McEniery, C., Carey, C., Davies, J. S., Barrett, T., Cockcroft, J. R., Paisey, R.

“…Background  Alström syndrome (AS) is a rare autosomal recessive condition characterized by retinal degeneration, childhood obesity, and severe insulin…”
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Perindopril: the reasonable choice in patients with coronary artery disease by Cockcroft, J R

“…Recent studies in patients with coronary artery disease (CAD) have suggested that angiotensin-converting enzyme (ACE) inhibitors may have benefits beyond blood…”
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HM3 Patients Do Not Have an Increased Pulsatility in Large, Muscular or Microcirculatory Arteries by Stöhr, E.J., Ji, R., Akiyama, K., Castagna, F., Pinsino, A., Cockcroft, J.R., Uriel, N., Yuzefpolskaya, M., Garan, R., Topkara, V., Takayama, H., Takeda, K., Naka, Y., Joshua, W.Z., McDonnell, B., Colombo, P.C.

“…It is well established that continuous-flow left ventricular assist devices (LVAD) reduce pulsatility in the circulation. Consequently, the addition of an…”
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Estimation of Mean Arterial Pressure Using Doppler and Pump Parameters in HeartMate 3 Patients by Pinsino, A., Mondellini, G.M., Castagna, F., Gaudig, A., Yuzefpolskaya, M., Uriel, N., Sayer, G., Takeda, K., Naka, Y., Cockcroft, J.R., Stohr, E.J., McDonnell, B., Colombo, P.C.

“…The optimal method for blood pressure (BP) measurement among pts implanted with HeartMate 3 (HM3), a centrifugal pump that features an artificial pulse, is…”
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Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria by Elliott, T G, Cockcroft, J R, Groop, P H, Viberti, G C, Ritter, J M

“…1. Microalbuminuria is a risk factor for cardiovascular disease in patients with insulin-dependent diabetes mellitus, and may be a marker of microvascular…”
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Assessment of Cerebrovascular Reserve in the Heart Failure Patients Supported with the HeartMate3 by Ji, R., Stohr, E.J., Akiyama, K., Amlani, A., Mondellini, G.M., Castagna, F., Pinsino, A., Cockcroft, J.R., Yuzefpolskaya, M., Topkara, V.K., Takayama, H., Takeda, K., Naka, Y., Uriel, N., Colombo, P.C., McDonnell, B., Willey, J.Z.

“…We previously showed that cerebrovascular reactivity (CVR) is reduced in heart failure (HF) patients and does not improve after left ventricular assist device…”
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P1.14 Non-Invasive Assessment of Cardiac Hemodynamic in Copd by Albarrati, A., Gale, N. S., Enright, S., Munnery, M., Munnery, I., Shale, D. J., Cockcroft, J. R.

“…Introduction Chronic obstructive pulmonary disease (COPD) is a systemic disease associated with impaired cardiac function. A reduction in stroke volume and…”
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The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer by SMITH, J. C, BENNETT, S, EVANS, L. M, KYNASTON, H. G, PARMAR, M, MASON, M. D, COCKCROFT, J. R, SCANLON, M. F, DAVIES, J. S

“…Sex hormones appear to play a pivotal role in determining cardiovascular risk. Androgen deprivation therapy for males with prostate cancer results in a…”
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Aortic Stiffness and Vitamin D are Independent Markers of Aortic Calcification in Patients with Peripheral Arterial Disease and in Healthy Subjects by Zagura, M, Serg, M, Kampus, P, Zilmer, M, Eha, J, Unt, E, Lieberg, J, Cockcroft, J.R, Kals, J

“…Abstract Objective Arterial stiffness is a significant determinant of cardiovascular risk and is related to vascular calcification. Vitamin D may regulate…”
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Correlation between baseline blood pressure and the brainstem FMRI response to isometric forearm contraction in human volunteers: a pilot study by Coulson, J M, Murphy, K, Harris, A D, Fjodorova, M, Cockcroft, J R, Wise, R G

“…It has been shown previously that changes in brainstem neural activity correlate with changes in both mean arterial pressure (MAP) and muscle sympathetic nerve…”
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Habitual Exercise and Blood Pressure: Age Dependency and Underlying Mechanisms by McDonnell, Barry J., Maki-Petaja, Kaisa M., Munnery, Margaret, Yasmin, Wilkinson, Ian B., Cockcroft, John R., McEniery, Carmel M.

“…BACKGROUND Regular exercise is associated with a reduction in cardiovascular risk, but the precise mechanisms responsible are unknown. The aim of the current…”
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