Search Results - "COCKBURN, I. A."

Protective and pathogenic roles of CD8+ T cells during malaria infection by HAFALLA, J. C. R., COCKBURN, I. A., ZAVALA, F.

“…SUMMARY CD8+ T cells play a key role in protection against pre‐erythrocytic stages of malaria infection. Many vaccine strategies are based on the idea of…”
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Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites by Tse, S-W, Cockburn, I A, Zhang, H, Scott, A L, Zavala, F

“…Sterile immunity against live Plasmodium infection can be achieved by immunization with radiation-attenuated sporozoites. This protection is known to be…”
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Flexible polygon‐mirror based laser scanning microscope platform for multiphoton in‐vivo imaging by Li, Y. X., Gautam, V., Brüstle, A., Cockburn, I. A., Daria, V. R., Gillespie, C., Gaus, K., Alt, C., Lee, W. M.

“…Commercial microscopy systems make use of tandem scanning i.e. either slow or fast scanning. We constructed, for the first time, an advanced control system…”
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Erythrocyte CR1 expression level does not correlate with a HindIII restriction fragment length polymorphism in Africans; implications for studies on malaria susceptibility by Rowe, J A, Raza, A, Diallo, D A, Baby, M, Poudiougo, B, Coulibaly, D, Cockburn, I A, Middleton, J, Lyke, K E, Plowe, C V, Doumbo, O K, Moulds, J M

“…Complement receptor 1 (CR1) expression level on erythrocytes is genetically determined, and in Caucasian populations is linked to high (H) and low (L)…”
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Erythrocyte complement receptor 1 (CR1) expression level is not associated with polymorphisms in the promoter or 3′ untranslated regions of the CR1 gene by Cockburn, I. A., Rowe, J. A.

“…Summary Complement receptor 1 (CR1) expression level on erythrocytes is genetically determined and is associated with high (H) and low (L) expression alleles…”
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A simple method for accurate quantification of complement receptor 1 on erythrocytes preserved by fixing or freezing by Cockburn, I.A, Donvito, B, Cohen, J.H.M, Rowe, J.A

“…The mean number of complement receptor 1 (CR1) molecules on erythrocytes differs between normal individuals within the range of 100–1000 molecules per cell. In…”
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Unique transcriptional profile of liver-resident memory CD8 super(+) T cells induced by immunization with malaria sporozoites by Tse, S-W, Cockburn, I A, Zhang, H, Scott, A L, Zavala, F

“…Sterile immunity against live Plasmodium infection can be achieved by immunization with radiation-attenuated sporozoites. This protection is known to be…”
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Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype by Aye, Racheal, Sutton, Henry J., Nduati, Eunice W., Kai, Oscar, Mwacharo, Jedida, Musyoki, Jennifer, Otieno, Edward, Wambua, Juliana, Bejon, Philip, Cockburn, Ian A., Ndungu, Francis M.

“…Atypical memory B cells (aMBCs) are found in elevated numbers in individuals exposed to malaria. A key question is whether malaria induces aMBCs as a result of…”
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Virulence of Malaria Is Associated with Differential Expression of Plasmodium falciparum var Gene Subgroups in a Case-Control Study by Kaestli, Mirjam, Cockburn, Ian A., Cortés, Alfred, Baea, Kay, Rowe, J. Alexandra, Beck, Hans-Peter

“…Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a major pathogenicity factor in falciparum malaria that mediates cytoadherence. PfEMP1 is…”
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A Human Complement Receptor 1 Polymorphism That Reduces Plasmodium falciparum Rosetting Confers Protection against Severe Malaria by Cockburn, Ian A., Mackinnon, Margaret J., O'Donnell, Angela, Allen, Stephen J., Moulds, Joann M., Baisor, Moses, Bockarie, Moses, Reeder, John C., Rowe, J. Alexandra

“…Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on uninfected RBCs to form clumps of…”
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IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites by Morrot, Alexandre, Hafalla, Julius C R, Cockburn, Ian A, Carvalho, Luzia H, Zavala, Fidel

“…IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after…”
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T cell memory in malaria by Cockburn, Ian A, Zavala, Fidel

“…The observation that individuals living in malaria endemic areas fail to develop sterilizing immunity to malaria infection has led to the assumption that…”
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Protective CD8⁺ T Cells Induced by Malaria Sporozoites Do Not Undergo Modulation of Interleukin-7 Receptor Expression by Morrot, Alexandre, Cockburn, Ian A, Overstreet, Michael, Rodríguez, Dolores, Zavala, Fidel

“…CD8⁺ T cells induced by Plasmodium yoelii sporozoites develop into protective memory cells without undergoing changes in interleukin-7 receptor [alpha]…”
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Use of DNA probes to distinguish sibling species of the Anopheles quadrimaculatus complex by Cockburn, A.F, Tarrant, C.A, Mitchell, S

“…Isozyme electrophoresis has traditionally been the method of choice for analyzing the genetic structure of populations. It can also be useful for…”
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