Search Results - "COCCUZZO SAMPAIO, Sandra"
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Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4
Published in Mediators of inflammation (01-01-2016)“…We investigated the effects of Crotoxin (CTX), the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, on Walker 256 tumor growth,…”
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2
Metagenomic insights into the plasma virome of Brazilian patients with prostate cancer
Published in Molecular & cellular oncology (2023)“…Growing evidence suggests that metavirome changes could be associated increased risk for malignant cell transformation. Considering Viruses have been proposed…”
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3
Inhibition of Macrophage Functions by the C-Terminus of Murine S100A9 Is Dependent on B-1 Cells
Published in Mediators of Inflammation (01-01-2014)“…The protein S100A9 plays a key role in the control of inflammatory response. The C-terminus of the murine S100A9 protein (mS100A9p) downregulates the spreading…”
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4
Crotoxin Modulates Events Involved in Epithelial-Mesenchymal Transition in 3D Spheroid Model
Published in Toxins (22-11-2021)“…Epithelial-mesenchymal transition (EMT) occurs in the early stages of embryonic development and plays a significant role in the migration and the…”
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5
A past and present overview of macrophage metabolism and functional outcomes
Published in Clinical science (1979) (15-06-2017)“…In 1986 and 1987, Philip Newsholme et al. reported macrophages utilize glutamine, as well as glucose, at high rates. These authors measured key enzyme…”
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Updated Insights into the Phylogenetics, Phylodynamics, and Genetic Diversity of Nipah Virus (NiV)
Published in Viruses (24-01-2024)“…Nipah virus (NiV), a biosafety level 4 agent, was first identified in human clinical cases during an outbreak in 1998 in Malaysia and Singapore. While flying…”
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Crotoxin Modulates Macrophage Phenotypic Reprogramming
Published in Toxins (01-10-2023)“…Macrophage plasticity is a fundamental feature of the immune response since it favors the rapid and adequate change of the functional phenotype in response to…”
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8
Crotoxin promotes macrophage reprogramming towards an antiangiogenic phenotype
Published in Scientific reports (12-03-2019)“…Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation…”
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Molecular frequency of human gemycircularvirus (GCYV) dna among blood donors from the Brazilian Amazon
Published in Transfusion clinique et biologique : journal de la Société française de transfusion sanguine (01-05-2024)“…•Gemycircularviruses are emerging group of viruses discovered by metagenomics in clinical samples.•The prevalence of Gemycircularvirus SL3 (GCYV-SL3) was…”
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10
Replacement of the Gamma by the Delta variant in Brazil: Impact of lineage displacement on the ongoing pandemic
Published in Virus evolution (2022)“…Abstract The coronavirus disease 2019 (COVID-19) epidemic in Brazil was driven mainly by the spread of Gamma (P.1), a locally emerged variant of concern (VOC)…”
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Correlating biological activity to thermo-structural analysis of the interaction of CTX with synthetic models of macrophage membranes
Published in Scientific reports (09-12-2021)“…The important pharmacological actions of Crotoxin (CTX) on macrophages, the main toxin in the venom of Crotalus durissus terrificus , and its important…”
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12
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations
Published in BMC public health (03-01-2023)“…Brazil has been dramatically hit by the SARS-CoV-2 pandemic and is a world leader in COVID-19 morbidity and mortality. Additionally, the largest country of…”
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Viral Metagenomics for the Identification of Emerging Infections in Clinical Samples with Inconclusive Dengue, Zika, and Chikungunya Viral Amplification
Published in Viruses (31-08-2022)“…Viral metagenomics is increasingly being used for the identification of emerging and re-emerging viral pathogens in clinical samples with unknown etiology. The…”
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14
Crotoxin Inhibits Endothelial Cell Functions in Two- and Three-dimensional Tumor Microenvironment
Published in Frontiers in pharmacology (04-08-2021)“…Antitumor property of Crotoxin (CTX), the major toxin from Crotalus durissus terrificus snake venom, has been demonstrated in experimental animal models and…”
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Correction: Bufalo et al. Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds. Cells 2022, 11 , 247
Published in Cells (Basel, Switzerland) (24-06-2024)“…In the original publication [...]…”
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16
Retrospective Spatio-Temporal Dynamics of Dengue Virus 1, 2 and 4 in Paraguay
Published in Viruses (30-05-2023)“…Dengue virus (DENV) has been a major public health concern in Paraguay, with frequent outbreaks occurring since early 1988. Although control measures have been…”
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Dynamics of SARS-CoV-2 Variants of Concern in Vaccination Model City in the State of Sao Paulo, Brazil
Published in Viruses (29-09-2022)“…From a country with one of the highest SARS-CoV-2 morbidity and mortality rates, Brazil has implemented one of the most successful vaccination programs…”
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ROS production in neutrophils from alloxan-induced diabetic rats treated in vivo with astaxanthin
Published in International immunopharmacology (2011)“…Astaxanthin (ASTA) is a carotenoid which has powerful antioxidant, anti-tumor, anti-diabetic, anti-inflammatory and cardioprotective properties. The present…”
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Heat-Labile Toxin from Enterotoxigenic Escherichia coli Causes Systemic Impairment in Zebrafish Model
Published in Toxins (12-06-2021)“…Heat-labile toxin I (LT-I), produced by strains of enterotoxigenic (ETEC), causes profuse watery diarrhea in humans. Different in vitro and in vivo models have…”
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Astaxanthin ameliorates the redox imbalance in lymphocytes of experimental diabetic rats
Published in Chemico-biological interactions (05-08-2010)“…Diabetes mellitus is a syndrome of impaired insulin secretion/sensitivity and frequently diagnosed by hyperglycemia, lipid abnormalities, and vascular…”
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