Search Results - "COBB, S"

Using expert perspectives to explore factors affecting choice of methods in safety analysis by Farooqi, A., Ryan, B., Cobb, S.

“…•Safety experts recognised the value of the safety II approach for improving system safety.•Some found difficulty in understanding concepts and applying FRAM…”
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The transition from bee-to-fly dominated communities with increasing elevation and greater forest canopy cover by McCabe, Lindsie M, Colella, Ella, Chesshire, Paige, Smith, Dave, Cobb, Neil S

“…Insect pollinator communities are thought to transition from bee-dominated communities at low elevations to fly-dominated communities at high elevations. We…”
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Woodland resilience to regional drought: Dominant controls on tree regeneration following overstorey mortality by Redmond, Miranda D., Weisberg, Peter J., Cobb, Neil S., Clifford, Michael J.

“…1. Drought events occurring under warmer temperatures (i.e. "hotter droughts") have resulted in widespread tree mortality across the globe, and may result in…”
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Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus by Hadjur, Suzana, Williams, Luke M., Ryan, Natalie K., Cobb, Bradley S., Sexton, Tom, Fraser, Peter, Fisher, Amanda G., Merkenschlager, Matthias

“…Cohesin branches out As well as its role in sister chromatid cohesion, the cohesin protein complex is thought be involved in the control of gene expression…”
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Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage by Koralov, Sergei B., Muljo, Stefan A., Galler, Gunther R., Krek, Azra, Chakraborty, Tirtha, Kanellopoulou, Chryssa, Jensen, Kari, Cobb, Bradley S., Merkenschlager, Matthias, Rajewsky, Nikolaus, Rajewsky, Klaus

“…To explore the role of Dicer-dependent control mechanisms in B lymphocyte development, we ablated this enzyme in early B cell progenitors. This resulted in a…”
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Outcomes of Synthetic Mesh in Contaminated Ventral Hernia Repairs by Carbonell, Alfredo M., DO, FACS, Criss, Cory N., MD, Cobb, William S., MD, FACS, Novitsky, Yuri W., MD, Rosen, Michael J., MD, FACS

“…Background Given the questionable long-term durability of biologic meshes, additional prosthetic options for ventral hernia repairs (VHR) in contaminated…”
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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR by Sauer, Stephan, Bruno, Ludovica, Hertweck, Arnulf, Finlay, David, Leleu, Marion, Spivakov, Mikhail, Knight, Zachary A, Cobb, Bradley S, Cantrell, Doreen, O'Connor, Eric, Shokat, Kevan M, Fisher, Amanda G, Merkenschlager, Matthias

“…Regulatory T (Treg) cells safeguard against autoimmunity and immune pathology. Because determinants of the Treg cell fate are not completely understood, we…”
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Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal by Weng, S.-M, McLeod, F, Bailey, M.E.S, Cobb, S.R

“…Abstract Rett syndrome (RTT), a disorder caused almost exclusively by mutations in the X-linked gene, MECP2 , has a phenotype thought to be primarily of…”
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Open Retromuscular Mesh Repair of Complex Incisional Hernia: Predictors of Wound Events and Recurrence by Cobb, William S., MD, FACS, Warren, Jeremy A., MD, Ewing, Joseph A., BS, Burnikel, Alex, Merchant, Miller, Carbonell, Alfredo M., DO, FACS

“…Background Mesh repair of incisional hernias has been consistently shown to diminish recurrence rates after repair, with an increased risk of infectious…”
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A role for Dicer in immune regulation by Cobb, Bradley S, Hertweck, Arnulf, Smith, James, O'Connor, Eric, Graf, Daniel, Cook, Terence, Smale, Stephen T, Sakaguchi, Shimon, Livesey, Frederick J, Fisher, Amanda G, Merkenschlager, Matthias

“…Micro RNAs (miRNAs) regulate gene expression at the posttranscriptional level. Here we show that regulatory T (T reg) cells have a miRNA profile distinct from…”
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Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms by Parelho, Vania, Hadjur, Suzana, Spivakov, Mikhail, Leleu, Marion, Sauer, Stephan, Gregson, Heather C., Jarmuz, Adam, Canzonetta, Claudia, Webster, Zoe, Nesterova, Tatyana, Cobb, Bradley S., Yokomori, Kyoko, Dillon, Niall, Aragon, Luis, Fisher, Amanda G., Merkenschlager, Matthias

“…Cohesins mediate sister chromatid cohesion, which is essential for chromosome segregation and postreplicative DNA repair. In addition, cohesins appear to…”
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Regional vegetation die-off in response to global-change-type drought by Breshears, D.D, Cobb, N.S, Rich, P.M, Price, K.P, Allen, C.D, Balice, R.G, Romme, W.H, Kastens, J.H, Floyd, M.L, Belnap, J

“…Future drought is projected to occur under warmer temperature conditions as climate change progresses, referred to here as global-change-type drought, yet…”
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Dicer-dependent pathways regulate chondrocyte proliferation and differentiation by Kobayashi, Tatsuya, Lu, Jun, Cobb, Bradley S, Rodda, Stephen J, McMahon, Andrew P, Schipani, Ernestina, Merkenschlager, Matthias, Kronenberg, Henry M

“…Small noncoding RNAs, microRNAs (miRNAs), bind to messenger RNAs through base pairing to suppress gene expression. Despite accumulating evidence that miRNAs…”
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Machine learning to determine optimal conditions for controlling the size of elastin-based particles by Cobb, Jared S., Engel, Alexandra, Seale, Maria A., Janorkar, Amol V.

“…This paper evaluates the aggregation behavior of a potential drug and gene delivery system that combines branched polyethyleneimine (PEI), a positively-charged…”
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Examining the effect of social distancing on the compound growth rate of COVID-19 at the county level (United States) using statistical analyses and a random forest machine learning model by Cobb, J.S., Seale, M.A.

“…The goal of the present work is to investigate trends among US counties and coronavirus disease 2019 (COVID-19) growth rates in relation to the existence of…”
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Forest habitats and plant communities strongly predicts Megachilidae bee biodiversity by McCabe, Lindsie M, Chesshire, Paige, Cobb, Neil S

“…Megachilidae is one of the United States' most diverse bee families, with 667 described species in 19 genera. Unlike other bee families, which are primarily…”
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Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome by McLeod, F, Ganley, R, Williams, L, Selfridge, J, Bird, A, Cobb, S.R

“…Highlights ► We show altered seizure threshold in a mouse model of Rett syndrome. ► Network level hyperexcitability is also revealed in brain slices from Rett…”
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Ceramic materials for porcelain veneers: Part II. Effect of material, shade, and thickness on translucency by Barizon, Karine T.L., DDS, MS, MS, Bergeron, Cathia, DMD, MS, Vargas, Marcos A., DDS, MS, Qian, Fang, PhD, Cobb, Deborah S., DDS, MS, Gratton, David G., DDS, MS, Geraldeli, Saulo, DDS, MS, PhD

“…Statement of problem Information regarding the differences in translucency among new ceramic systems is lacking. Purpose The purpose of this study was to…”
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Precipitation thresholds and drought-induced tree die-off: insights from patterns of Pinus edulis mortality along an environmental stress gradient by Clifford, Michael J., Royer, Patrick D., Cobb, Neil S., Breshears, David D., Ford, Paulette L.

“…Recent regional tree die-off events appear to have been triggered by a combination of drought and heat – referred to as ‘global-change-type drought’. To…”
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Risks of subsequent abdominal operations after laparoscopic ventral hernia repair by Patel, Puraj P., Love, Michael W., Ewing, Joseph A., Warren, Jeremy A., Cobb, William S., Carbonell, Alfredo M.

“…Introduction Laparoscopic ventral hernia repair (LVHR) with intraperitoneal mesh placement is well established; however, the fate of patients requiring future…”
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