Search Results - "CMIELOVA, JANA"

Protein and its function based on a subcellular localization by Ćmielová, Jana, Řezáčová, M.

“…Protein p21Cip1/Waf1 is a cyclin‐dependent kinase inhibitor, which is important in the response of cells to genotoxic stress and a major transcriptional target…”
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Boldine Inhibits Mouse Mammary Carcinoma In Vivo and Human MCF-7 Breast Cancer Cells In Vitro by Tomšík, Pavel, Mičuda, Stanislav, Muthná, Darina, Čermáková, Eva, Havelek, Radim, Rudolf, Emil, Hroch, Miloš, Kadová, Zuzana, Řezáčová, Martina, Ćmielová, Jana, Živný, Pavel

“…Boldine is an aporphine alkaloid widely consumed in the folk medicine of some regions. Its anticancer potential has been shown but not yet elucidated. We…”
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[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study by Tomšík, Pavel, Muthná, Darina, Řezáčová, Martina, Mičuda, Stanislav, Ćmielová, Jana, Hroch, Miloš, Endlicher, René, Červinková, Zuzana, Rudolf, Emil, Hann, Stephan, Stíbal, David, Therrien, Bruno, Süss-Fink, Georg

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Identification of Microflora in a Biological Brewer’s Wort Acidification Process Run Continuously for 20 Years by Hutzler, Mathias, Čmielová, Jana, Frank, Tobias, Brandl, Andreas, Jacob, Fritz, Michel, Maximilian

“…Biological acidification is a common and beneficial way for breweries to adjust the pH value of their mash or wort to improve enzymatic activity during…”
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Changes in the response of MCF-7 cells to ionizing radiation after the combination of ATM and DNA-PK inhibition by Ćmielová, Jana, Havelek, Radim, Vávrová, Jiřina, Řezáčová, Martina

“…The aim of the present study is to evaluate the role of ATM (KU55933) and DNA-PK (NU7441) inhibitors in the repair of double-strand breaks and downstream…”
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Differences in vanadocene dichloride and cisplatin effect on MOLT-4 leukemia and human peripheral blood mononuclear cells by Havelek, Radim, Siman, Pavel, Cmielova, Jana, Stoklasova, Alena, Vavrova, Jirina, Vinklarek, Jaromir, Knizek, Jiri, Rezacova, Martina

“…Modern chemotherapy is interested in developing new agents with high efficiency of treatment in low-dose medication strategies, lower side toxicity and…”
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Specific inhibition of Wee1 kinase and Rad51 recombinase: a strategy to enhance the sensitivity of leukemic T-cells to ionizing radiation-induced DNA double-strand breaks by Havelek, Radim, Cmielova, Jana, Kralovec, Karel, Bruckova, Lenka, Bilkova, Zuzana, Fousova, Ivana, Sinkorova, Zuzana, Vavrova, Jirina, Rezacova, Martina

“…Present-day oncology sees at least two-thirds of cancer patients receiving radiation therapy as a part of their anticancer treatment. The objectives of the…”
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Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments by Cmielova, Jana, Havelek, Radim, Soukup, Tomas, Jiroutová, Alena, Visek, Benjamin, Suchánek, Jakub, Vavrova, Jirina, Mokry, Jaroslav, Muthna, Darina, Bruckova, Lenka, Filip, Stanislav, English, Denis, Rezacova, Martina

“…Purpose: Mesenchymal stem cells isolated from bone marrow (BM-MSC) and periodontal ligament (PLSC) are cells with high proliferative potential and ability to…”
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Boldine and related aporphines: from antioxidant to antiproliferative properties by Muthna, Darina, Cmielova, Jana, Tomsik, Pavel, Rezacova, Martina

“…Plant and folk medicine represent nowadays a source of either new therapeutic substances or substrates for drug synthesis. One such promising group for…”
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The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction by SUCHA, LENKA, HROCH, MILOS, REZACOVA, MARTINA, RUDOLF, EMIL, HAVELEK, RADIM, SISPERA, LUDEK, CMIELOVA, JANA, KOHLEROVA, RENATA, BEZROUK, ALES, TOMSIK, PAVEL

“…In recent years, α-tomatine has been studied for its anticancer activity. In the present study, we focused on the cytotoxic effect of α-tomatine in the MCF-7…”
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Repair pathway crosstalk in genome stability maintenance through BRCA1/2‐mediated homologous recombination (352.1) by Cooper, Priscilla, Trego, Kelly, Groesser, Torsten, Parplys, Ann, Cmielova, Jana, Wiese, Claudia, Sung, Patrick, Campisi, Judith

“…XPG is an endonuclease required for nucleotide excision repair with important non‐enzymatic roles in base excision repair (BER) and transcription‐coupled…”
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Irradiation of adult human dental pulp stem cells provokes activation of p53, cell cycle arrest, and senescence but not apoptosis by Muthna, Darina, Soukup, Tomas, Vavrova, Jirina, Mokry, Jaroslav, Cmielova, Jana, Visek, Benjamin, Jiroutova, Alena, Havelek, Radim, Suchanek, Jakub, Filip, Stanislav, English, Denis, Rezacova, Martina

“…Adult human dental pulp contains stem cells (DPSCs) that are capable of differentiation into osteoblasts, odontoblasts, adipocytes, and neuronal-like cells…”
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The effect of ATM kinase inhibition on the initial response of human dental pulp and periodontal ligament mesenchymal stem cells to ionizing radiation by Cmielova, Jana, Havelek, Radim, Kohlerova, Renata, Soukup, Tomas, Bruckova, Lenka, Suchanek, Jakub, Vavrova, Jirina, Mokry, Jaroslav, Rezacova, Martina

“…Abstract Purpose: This study evaluates early changes in human mesenchymal stem cells (MSC) isolated from dental pulp and periodontal ligament after…”
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p21Cip1/Waf1 protein and its function based on a subcellular localization [corrected] by Cmielová, Jana, Rezáčová, M

“…Protein p21(Cip1/Waf1) is a cyclin-dependent kinase inhibitor, which is important in the response of cells to genotoxic stress and a major transcriptional…”
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Subcellular Localization of Proteins Responding to Mitoxantrone-Induced DNA Damage in Leukaemic Cells by Ćmielová, J, Lesná, M, Řezáčová, M

“…The aim of the present study was to investigate the subcellular localization of proteins participating in the double-strand break response pathway - p53, Mdm2,…”
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