Search Results - "CM Hutter"

Genetic Causes of Monogenic Heterozygous Familial Hypercholesterolemia: A HuGE Prevalence Review by Austin, Melissa A., Hutter, Carolyn M., Zimmern, Ron L., Humphries, Steve E.

“…The clinical phenotype of heterozygous familial hypercholesterolemia (FH) is characterized by increased plasma levels of total cholesterol and low density…”
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Familial Hypercholesterolemia and Coronary Heart Disease: A HuGE Association Review by Austin, Melissa A., Hutter, Carolyn M., Zimmern, Ron L., Humphries, Steve E.

“…Familial hypercholesterolemia (FH) is an autosomal disorder characterized by increased levels of total cholesterol and low density lipoprotein cholesterol. The…”
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Familial Hypercholesterolemia, Peripheral Arterial Disease, and Stroke: A HuGE Minireview by Hutter, Carolyn M., Austin, Melissa A., Humphries, Steve E.

“…Heterozygous familial hypercholesterolemia (FH) is an autosomal dominant disorder known to be associated with elevated cholesterol levels and increased risk of…”
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Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans by Hutter, Carolyn M., Austin, Melissa A., Farin, Federico M., Viernes, Hannah-Malia, Edwards, Karen L., Leonetti, Donna L., McNeely, Marguerite J., Fujimoto, Wilfred Y.

“…The LIPG gene on chromosome 18 encodes for endothelial lipase, a member of the triglyceride lipase family. Mouse models suggest that variation in LIPG…”
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The mutation rates of di-, tri- and tetranucleotide repeats in Drosophila melanogaster by Schug, M D, Hutter, C M, Wetterstrand, K A, Gaudette, M S, Mackay, T F, Aquadro, C F

“…In a recent study, we reported that the combined average mutation rate of 10 di-, 6 tri-, and 8 tetranucleotide repeats in Drosophila melanogaster was 6.3 x…”
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Microsatellite variation in Drosophila melanogaster and Drosophila simulans: a reciprocal test of the ascertainment bias hypothesis by Hutter, C M, Schug, M D, Aquadro, C F

“…Interspecific comparisons of microsatellite loci have repeatedly shown that the loci are longer and more variable in the species from which they are derived…”
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distribution and frequency of microsatellite loci in Drosophila melanogaster by Schug, M.D, Wetterstrand, K.A, Gaudette, M.S, Lim, R.H, Hutter, C.M, Aquadro, C.F

“…We report the results of a comprehensive search of Drosophila melanogaster DNA sequences in GenBank for di‐, tri‐, and tetranucleotide repeats of more than…”
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Directional evolution of size coupled with ascertainment bias for variation in Drosophila microsatellites by Amos, William, Hutter, Carolyn M, Schug, Malcolm D, Aquadro, Charles F

“…Species-specific differences in microsatellite locus length and ascertainment bias have both been proposed to explain differences in microsatellite variability…”
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Genetic variation and differentiation at microsatellite loci in Drosophila simulans: evidence for founder effects in New World populations by Irvin, S.D. (Cornell University, Ithaca, NY.), Wetterstrand, K.A, Hutter, C.M, Aquadro, C.F

“…Drosophila simulans isofemale lines from Africa, South America, and two locations in North America were surveyed for variation at 16 microsatellite loci on the…”
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Competition between mitochondrial haplotypes in distinct nuclear genetic environments: Drosophila pseudoobscura vs. D. persimilis by Hutter, C.M. (Brown University, Providence, RI.), Rand, D.M

“…A test for coadaptation of nuclear and mitochondrial genomes was performed using the sibling species, Drosophila pseudoobscura and D. persimilis. Two lines of…”
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Characterization of a highly conserved gene (OS4) amplified with CDK4 in human sarcomas by SU, Y. A, LEE, M. M, HUTTER, C. M, MELTZER, P. S

“…Amplification and overexpression of genes involved in cellular growth control occur frequently in human cancers. Here, we report characterization of the full…”
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Mutation and evolution of microsatellites in Drosophila melanogaster by Schug, M D, Hutter, C M, Noor, M A, Aquadro, C F

“…Levels of nucleotide polymorphism in the Drosophila melanogaster genome are correlated with rates of recombination. This relationship may be due to hitchhiking…”
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The Impact Of Violations Of Core Conditions Underlying Mendelian Randomization: A Simulation Study by CM Hutter, Rice, K.M

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Comparison of single-nucleotide polymorphisms and microsatellites in detecting quantitative trait loci for alcoholism: the Collaborative Study on the Genetics of Alcoholism by Kim, Helen, Hutter, Carolyn M, Monks, Stephanie A, Edwards, Karen L

“…The feasibility of effectively analyzing high-density single nucleotide polymorphism (SNP) maps in whole genome scans of complex traits is not known. The…”
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