Search Results - "CLUFF, W"

Monophosphoryl lipid A (MPL) as an adjuvant for anti-cancer vaccines: clinical results by Cluff, Christopher W

“…As technological advances allow for the identification of tumor-associated antigens (TAAs) against which adaptive immune responses can be raised, efforts to…”
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Structure-Activity Relationship of Synthetic Toll-like Receptor 4 Agonists by Stöver, Axel G., Da Silva Correia, Jean, Evans, Jay T., Cluff, Christopher W., Elliott, Mark W., Jeffery, Eric W., Johnson, David A., Lacy, Michael J., Baldridge, Jory R., Probst, Peter, Ulevitch, Richard J., Persing, David H., Hershberg, Robert M.

“…Important questions remain regarding the impact of variations in the structure of the lipid A portion of lipopolysaccharide on activation of cells via the…”
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Synthetic Toll-Like Receptor 4 Agonists Stimulate Innate Resistance to Infectious Challenge by CLUFF, Christopher W, BALDRIDGE, Jory R, HERSHBERG, Robert M, PERSING, David H, STÖVER, Axel G, EVANS, Jay T, JOHNSON, David A, LACY, Michael J, CLAWSON, Valerie G, YORGENSEN, Vonnie M, JOHNSON, Craig L, LIVESAY, Mark T

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Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529 by Evans, Jay T, Cluff, Christopher W, Johnson, David A, Lacy, Michael J, Persing, David H, Baldridge, Jory R

“…MPL (Corixa) adjuvant is a chemically modified derivative of lipopolysaccharide that displays greatly reduced toxicity while maintaining most of the…”
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Band structures and shape coexistence in 187Pt by Hojman, D., Cardona, M. A., Roussière, B., Sauvage, J., Riley, M. A., Tabor, S. L., Hoffman, C. R., Aguilar, A., Cluff, W. T., Hinners, T., Lagergren, K., Lee, S., Perry, M., Pipidis, A., Tripathi, V.

“…High-spin states in 187 Pt have been studied by means of γ-ray spectroscopy techniques. Known bands have been significantly extended and new bands have been…”
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Effect of site-directed mutagenic alterations on ADP-ribosyltransferase activity of the A subunit of Escherichia coli heat-labile enterotoxin by LOBET, T, CLUFF, C. W, CIEPLAK, W. JR

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Cyclosporine inhibits macrophage-mediated antigen presentation by Palay, DA, Cluff, CW, Wentworth, PA, Ziegler, HK

“…The influence of cyclosporine on antigen-specific, macrophage-dependent T cell activation was analyzed in vitro. Murine T cell activation by antigens derived…”
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Reactive oxygen and nitrogen intermediates and products from polyamine degradation are Babesiacidal in vitro by Johnson, W C, Cluff, C W, Goff, W L, Wyatt, C R

“…Products released from activated macrophages have been demonstrated to have microbicidal activity against a variety of microorganisms. Reactive oxygen…”
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Intracellular hemolysin-producing Listeria monocytogenes strains inhibit macrophage-mediated antigen processing by CLUFF, C. W, GARCIA, M, ZIEGLER, H. K

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Antiischemic Effect of Monophosphoryl Lipid A in Conscious Rabbits with Hypercholesterolemia and Atherosclerosis by Szilvássy, Zoltán, Ferdinandy, Péter, Cluff, Christopher W, Elliott, Gary T

“…We studied whether monophosphoryl lipid A (MLA), an endotoxin derivative, protected the heart from planned ischemia in hypercholesterolemic conscious rabbits…”
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The ‘Ethereal’ nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics by Bazin, Hélène G., Murray, Tim J., Bowen, William S., Mozaffarian, Afsaneh, Fling, Steven P., Bess, Laura S., Livesay, Mark T., Arnold, Jeffrey S., Johnson, Craig L., Ryter, Kendal T., Cluff, Christopher W., Evans, Jay T., Johnson, David A.

“…The novel ether lipid AGPs 4 and 5 were synthesized by a highly convergent method and evaluated along with their ester counterparts for TLR4 activity in both…”
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Role of listeriolysin-O (LLO) in the T lymphocyte response to infection with Listeria monocytogenes. Identification of T cell epitopes of LLO by Safley, SA, Cluff, CW, Marshall, NE, Ziegler, HK

“…Using a murine model, we investigated the role of the bacterial exotoxin listeriolysin O (LLO) in cellular immunity to Listeria monocytogenes. A correlation…”
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Assessment of bovine mononuclear phagocytes and neutrophils for induced L-arginine-dependent nitric oxide production by Goff, Will L., Carl Johnson, W., Wyatt, Carol R., Cluff, Christopher W.

“…Microbicidal activity of reactive oxygen intermediates and reactive nitrogen intermediates has been described from both murine and human cytokine activated…”
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Babesia bovis Immunity: In Vitro and in Vivo Evidence for IL-10 Regulation of IFN-γ and iNOS by GOFF, W. L., JOHNSON, W. C., CLUFF, C. W.

“…IL-10 has been shown to have profound immunoregulatory attributes and in the bovine appears to downregulate both Th1- and Th2-like responses. Using RT-PCR, we…”
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Differential requirements for the processing and presentation of soluble and particulate bacterial antigens by macrophages by Ziegler, H K, Orlin, C A, Cluff, C W

“…The requirements for antigen processing and presentation by macrophages using various forms of antigens derived from Listeria monocytogenes have been studied…”
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Inhibition of macrophage-mediated antigen presentation by hemolysin- producing Listeria monocytogenes [published erratum appears in J Immunol 1988 Apr 1;140(7):2477] by Cluff, CW, Ziegler, HK

“…T lymphocytes and macrophages from Listeria-infected mice were used to evaluate the processing and presentation of live Listeria monocytogenes in vitro…”
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Astrophysical Reaction Rate for the Neutron-Generator Reaction C 13 ( α , n ) O 16 in Asymptotic Giant Branch Stars by Johnson, E. D., Rogachev, G. V., Mukhamedzhanov, A. M., Baby, L. T., Brown, S., Cluff, W. T., Crisp, A. M., Diffenderfer, E., Goldberg, V. Z., Green, B. W., Hinners, T., Hoffman, C. R., Kemper, K. W., Momotyuk, O., Peplowski, P., Pipidis, A., Reynolds, R., Roeder, B. T.

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An early response to lipopolysaccharide is the elicitation of macrophages specialized for antigen degradation with negative regulatory effects on the induction of specific immune responses by CLUFF, C. W, ZIEGLER, H. K

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Target structure independent 7Li elastic scattering at lowmomentum transfers by Momotyuk, O.A., Keeley, N., Kemper, K.W., Roeder, B.T., Crisp,A.M., Cluff, W., Schmidt, B.G., Wiedeking, M., Marechal, F., Rusek, K., Mezhevych, S.Yu, Liendo, J.

“…Analyzing powers and cross sections for the elastic scattering of polarized 7Li by targets of 6Li, 7Li and 12C are shown to depend only on the properties of…”
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Target structure independent Li→7 elastic scattering at low momentum transfers by Momotyuk, O.A., Keeley, N., Kemper, K.W., Roeder, B.T., Crisp, A.M., Cluff, W., Schmidt, B.G., Wiedeking, M., Maréchal, F., Rusek, K., Mezhevych, S.Yu, Liendo, J.

“…Analyzing powers and cross sections for the elastic scattering of polarized 7Li by targets of 6Li, 7Li and 12C are shown to depend only on the properties of…”
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