Search Results - "CLOP, Alex"
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Identification of circular RNAs in porcine sperm and evaluation of their relation to sperm motility
Published in Scientific reports (14-05-2020)“…Circular RNAs (circRNAs) are emerging as a novel class of noncoding RNAs which potential role as gene regulators is quickly gaining interest. circRNAs have…”
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Exploring the ovine sperm transcriptome by RNAseq techniques. I Effect of seasonal conditions on transcripts abundance
Published in PloS one (14-03-2022)“…Understanding the cell molecular changes occurring as a results of climatic circumstances is crucial in the current days in which climate change and global…”
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A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
Published in Nature genetics (01-07-2006)“…Texel sheep are renowned for their exceptional meatiness. To identify the genes underlying this economically important feature, we performed a whole-genome…”
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A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine
Published in Genetics selection evolution (Paris) (08-12-2020)“…Genetic pressure in animal breeding is sparking the interest of breeders for selecting elite boars with higher sperm quality to optimize ejaculate doses and…”
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A RNA-Seq Analysis to Describe the Boar Sperm Transcriptome and Its Seasonal Changes
Published in Frontiers in genetics (16-04-2019)“…Understanding the molecular basis of cell function and ultimate phenotypes is crucial for the development of biological markers. With this aim, several RNA-seq…”
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Micrococcal nuclease sequencing of porcine sperm suggests enriched co-location between retained histones and genomic regions related to semen quality and early embryo development
Published in PeerJ (San Francisco, CA) (21-06-2023)“…The mammalian spermatozoon has a unique chromatin structure in which the majority of histones are replaced by protamines during spermatogenesis and a small…”
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Assessing the levels of intraspecific admixture and interspecific hybridization in Iberian wild goats (Capra pyrenaica)
Published in Evolutionary applications (01-11-2021)“…Iberian wild goats (Capra pyrenaica, also known as Iberian ibex, Spanish ibex, and Spanish wild goat) underwent strong genetic bottlenecks during the 19th and…”
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An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element
Published in PloS one (19-08-2013)“…Psoriasis is an immune-mediated skin disorder that is inherited as a complex genetic trait. Although genome-wide association scans (GWAS) have identified 36…”
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Characterization of the Impact of Density Gradient Centrifugation on the Profile of the Pig Sperm Transcriptome by RNA-Seq
Published in Frontiers in veterinary science (19-07-2021)“…RNA-Seq data from human semen suggests that the study of the sperm transcriptome requires the previous elimination from the ejaculates of somatic cells…”
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A genome-wide association study of female sexual dysfunction
Published in PloS one (11-04-2012)“…Female sexual dysfunction (FSD) is an important but controversial problem with serious negative impact on women's quality of life. Data from twin studies have…”
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A systems model for immune cell interactions unravels the mechanism of inflammation in human skin
Published in PLoS computational biology (01-12-2010)“…Inflammation is characterized by altered cytokine levels produced by cell populations in a highly interdependent manner. To elucidate the mechanism of an…”
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Differential expression of sarcoplasmic proteins in four heterogeneous ovine skeletal muscles
Published in Proteomics (Weinheim) (01-01-2007)“…Fiber‐type distribution is known to vary widely within and between muscles according to differences in muscle functions. 2‐DE and MALDI‐MS were used to…”
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A QTL for intramuscular fat and backfat thickness is located on porcine chromosome 6
Published in Mammalian genome (01-04-2000)“…The use of molecular markers is an accessible technology with wide applications. One of them is the construction of genetic maps and the location of…”
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Genomic, transcriptomic and epigenomic analysis towards the understanding of porcine semen quality traits. Past, current and future trends
Published in Animal reproduction science (01-10-2024)“…The importance of boar reproductive traits, including semen quality, in the sustainability of pig production system is increasingly being acknowledged by…”
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Insights into the importance of miRNA-related polymorphisms to heart disease
Published in Human mutation (01-08-2009)Get full text
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A compendium of genetic regulatory effects across pig tissues
Published in Nature genetics (01-01-2024)“…The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock,…”
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PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs
Published in Nucleic acids research (05-01-2024)“…Abstract To fully unlock the potential of pigs as both agricultural species for animal-based protein food and biomedical models for human biology and disease,…”
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Low mitochondrial diversity in native Italian pig breeds is consistent with the occurrence of strong population bottlenecks
Published in Animal genetics (01-12-2017)Get full text
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A pilot RNA-seq study in 40 pietrain ejaculates to characterize the porcine sperm microbiome
Published in Theriogenology (01-11-2020)“…The microbiome plays a key role in homeostasis and health and it has been also linked to fertility and semen quality in several animal species including swine…”
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A technical assessment of the porcine ejaculated spermatozoa for a sperm-specific RNA-seq analysis
Published in Systems biology in reproductive medicine (04-07-2018)“…The study of the boar sperm transcriptome by RNA-seq can provide relevant information on sperm quality and fertility and might contribute to animal breeding…”
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