Search Results - "CLIFFORD LANE, H"
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Covid-19 — Navigating the Uncharted
Published in The New England journal of medicine (26-03-2020)“…Fauci, Lane, and Redfield comment on the early clinical features and epidemiology of cases reported in Wuhan, China, along with current mortality data, noting…”
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Four Decades of HIV/AIDS — Much Accomplished, Much to Do
Published in The New England journal of medicine (02-07-2020)“…Considering the spectacular scientific advances that have been made over nearly four decades, it is conceivable that with optimal implementation of available…”
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A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics
Published in The New England journal of medicine (12-12-2019)“…Ebola transmission has been ongoing in the Democratic Republic of Congo since August 2018. In this trial of MAb114, REGN-EB3, remdesivir, and ZMapp (as the…”
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DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)
Published in Nucleic acids research (05-07-2022)“…Abstract DAVID is a popular bioinformatics resource system including a web server and web service for functional annotation and enrichment analyses of gene…”
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Research in the Context of a Pandemic
Published in The New England journal of medicine (25-02-2021)“…Clifford Lane and Anthony Fauci comment on the findings of the RECOVERY trial of dexamethasone to treat Covid-19, noting that scientifically robust and…”
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Defective HIV-1 proviruses produce viral proteins
Published in Proceedings of the National Academy of Sciences - PNAS (18-02-2020)“…HIV-1 proviruses persist in the CD4⁺ T cells of HIV-infected individuals despite years of combination antiretroviral therapy (cART) with suppression of HIV-1…”
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DAVID-WS: a stateful web service to facilitate gene/protein list analysis
Published in Bioinformatics (Oxford, England) (01-07-2012)“…The database for annotation, visualization and integrated discovery (DAVID), which can be freely accessed at http://david.abcc.ncifcrf.gov/, is a web-based…”
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SARS-CoV-2 Vaccines: Much Accomplished, Much to Learn
Published in Annals of internal medicine (01-05-2021)“…Over the next weeks and months, physicians will face questions regarding the science, safety, and efficacy of the first wave of severe acute respiratory…”
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COVID-19: towards controlling of a pandemic
Published in The Lancet (British edition) (28-03-2020)“…Most national response strategies include varying levels of contact tracing and self-isolation or quarantine; promotion of public health measures, including…”
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Molecular Imaging of Infections: Advancing the Search for the Hidden Enemy
Published in The Journal of infectious diseases (03-10-2023)“…Abstract Even before the coronavirus disease 2019 pandemic, infections were a major threat to human health, as the third leading cause of death and the leading…”
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Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection
Published in The New England journal of medicine (27-08-2015)“…When to start antiretroviral therapy for HIV infection on the basis of the CD4+ count has been controversial. In a global randomized trial, treatment of…”
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A Longitudinal Study of COVID-19 Sequelae and Immunity: Baseline Findings
Published in Annals of internal medicine (01-07-2022)“…A substantial proportion of persons who develop COVID-19 report persistent symptoms after acute illness. Various pathophysiologic mechanisms have been…”
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Phase 2 Placebo-Controlled Trial of Two Vaccines to Prevent Ebola in Liberia
Published in The New England journal of medicine (12-10-2017)“…Ebola remains a global threat. In a randomized, controlled trial to assess the safety and immunogenicity of two vaccines against Ebola virus disease in…”
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Defective HIV-1 proviruses produce novel protein-coding RNA species in HIV-infected patients on combination antiretroviral therapy
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2016)“…Despite years of plasma HIV-RNA levels <40 copies per milliliter during combination antiretroviral therapy (cART), the majority of HIV-infected patients…”
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Inflammation, coagulation and cardiovascular disease in HIV-infected individuals
Published in PloS one (10-09-2012)“…The SMART study was a trial of intermittent use of antiretroviral therapy (ART) (drug conservation [DC]) versus continuous use of ART (viral suppression [VS])…”
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DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis
Published in BMC bioinformatics (02-11-2007)“…Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases…”
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A Longitudinal Study of Ebola Sequelae in Liberia
Published in The New England journal of medicine (07-03-2019)“…Ebola virus causes severe illness, often leading to death. Little is known about the health sequelae of those who survive infection. In this report, health…”
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The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
Published in Genome biology (04-09-2007)“…The DAVID Gene Functional Classification Tool http://david.abcc.ncifcrf.gov uses a novel agglomeration algorithm to condense a list of genes or associated…”
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DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
Published in Nucleic acids research (01-07-2007)“…All tools in the DAVID Bioinformatics Resources aim to provide functional interpretation of large lists of genes derived from genomic studies. The newly…”
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Inflammatory and coagulation biomarkers and mortality in patients with HIV infection
Published in PLoS medicine (01-10-2008)“…In the Strategies for Management of Anti-Retroviral Therapy trial, all-cause mortality was higher for participants randomized to intermittent, CD4-guided…”
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