Search Results - "CLEUTJENS, Jack P"

Cell turnover and detritus production in marine sponges from tropical and temperate benthic ecosystems by Alexander, Brittany E, Liebrand, Kevin, Osinga, Ronald, van der Geest, Harm G, Admiraal, Wim, Cleutjens, Jack P M, Schutte, Bert, Verheyen, Fons, Ribes, Marta, van Loon, Emiel, de Goeij, Jasper M

“…This study describes in vivo cell turnover (the balance between cell proliferation and cell loss) in eight marine sponge species from tropical coral reef,…”
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MicroRNA‐18 and microRNA‐19 regulate CTGF and TSP‐1 expression in age‐related heart failure by van Almen, Geert C., Verhesen, Wouter, van Leeuwen, Rick E. W., van de Vrie, Mathijs, Eurlings, Casper, Schellings, Mark W. M., Swinnen, Melissa, Cleutjens, Jack P. M., van Zandvoort, Marc A. M. J., Heymans, Stephane, Schroen, Blanche

“…Summary To understand the process of cardiac aging, it is of crucial importance to gain insight into the age‐related changes in gene expression in the…”
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Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis by Sluimer, Judith C., MSc, Gasc, Jean-Marie, PhD, van Wanroij, Job L., MD, Kisters, Natasja, BSc, Groeneweg, Mathijs, MSc, Sollewijn Gelpke, Maarten D., MSc, Cleutjens, Jack P., PhD, van den Akker, Luc H., MD, Corvol, Pierre, MD, PhD, Wouters, Bradly G., PhD, Daemen, Mat J., MD, PhD, Bijnens, Ann-Pascale J., PhD

“…Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis Judith C…”
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Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions by Hoeksema, Marten A, Gijbels, Marion JJ, Van den Bossche, Jan, van der Velden, Saskia, Sijm, Ayestha, Neele, Annette E, Seijkens, Tom, Stöger, J Lauran, Meiler, Svenja, Boshuizen, Marieke CS, Dallinga‐Thie, Geesje M, Levels, Johannes HM, Boon, Louis, Mullican, Shannon E, Spann, Nathanael J, Cleutjens, Jack P, Glass, Chris K, Lazar, Mitchell A, de Vries, Carlie JM, Biessen, Erik AL, Daemen, Mat JAP, Lutgens, Esther, de Winther, Menno PJ

“…Macrophages are key immune cells found in atherosclerotic plaques and critically shape atherosclerotic disease development. Targeting the functional repertoire…”
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Limited additive value of the Ki‐67 proliferative index on patient survival in World Health Organization‐classified pulmonary carcinoids by Swarts, Dorian R A, Rudelius, Martina, Claessen, Sandra M H, Cleutjens, Jack P, Seidl, Stefan, Volante, Marco, Ramaekers, Frans C S, Speel, Ernst J M

“…Aims Currently pulmonary carcinoids are separated into typical and atypical based on mitotic count and presence of necrosis, according to the World Health…”
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Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis by Chatrou, Martijn L L, Cleutjens, Jack P, van der Vusse, Ger J, Roijers, Ruben B, Mutsaers, Peter H A, Schurgers, Leon J

“…Vascular calcification is associated with poor cardiovascular outcome. Histochemical analysis of calcification and the expression of proteins involved in…”
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SOX2 expression in the pathogenesis of premalignant lesions of the uterine cervix: its histo-topographical distribution distinguishes between low- and high-grade CIN by Moshi, Jobran M., Ummelen, Monique, Broers, Jos L. V., Smedts, Frank, Van de Vijver, Koen K., Cleutjens, Jack P. M., Litjens, Rogier J. N. T. M., Ramaekers, Frans C. S., Hopman, Anton H. N.

“…SOX2 expression in high-grade cervical intraepithelial neoplasia (CIN3) and cervical squamous cell carcinoma is increased compared to that in the normal…”
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Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction by Schellings, Mark W M, Vanhoutte, Davy, Swinnen, Melissa, Cleutjens, Jack P, Debets, Jacques, van Leeuwen, Rick E W, d'Hooge, Jan, Van de Werf, Frans, Carmeliet, Peter, Pinto, Yigal M, Sage, E Helene, Heymans, Stephane

“…The matricellular protein SPARC (secreted protein, acidic and rich in cysteine, also known as osteonectin) mediates cell-matrix interactions during wound…”
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Microcalcifications in Early Intimal Lesions of Atherosclerotic Human Coronary Arteries by Roijers, Ruben B, Debernardi, Nicola, Cleutjens, Jack P.M, Schurgers, Leon J, Mutsaers, Peter H.A, van der Vusse, Ger J

“…Although calcium (Ca) precipitation may play a pathogenic role in atherosclerosis, information on temporal patterns of microcalcifications in human coronary…”
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Reversal of Hypoxia in Murine Atherosclerosis Prevents Necrotic Core Expansion by Enhancing Efferocytosis by Marsch, Elke, Theelen, Thomas L, Demandt, Jasper A.F, Jeurissen, Mike, van Gink, Mathijs, Verjans, Robin, Janssen, Anique, Cleutjens, Jack P, Meex, Steven J.R, Donners, Marjo M, Haenen, Guido R, Schalkwijk, Casper G, Dubois, Ludwig J, Lambin, Philippe, Mallat, Ziad, Gijbels, Marion J, Heemskerk, Johan W.M, Fisher, Edward A, Biessen, Erik A.L, Janssen, Ben J, Daemen, Mat J.A.P, Sluimer, Judith C

“…OBJECTIVE—Advanced murine and human plaques are hypoxic, but it remains unclear whether plaque hypoxia is causally related to atherogenesis. Here, we test the…”
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Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model by Jetten, Nadine, Donners, Marjo M P C, Wagenaar, Allard, Cleutjens, Jack P M, van Rooijen, Nico, de Winther, Menno P J, Post, Mark J

“…Enhancement of collateral development in coronary or peripheral artery disease is a therapeutic target, but it has proven difficult to achieve. Macrophages are…”
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Chorioamnionitis induces changes in ovine pulmonary endogenous epithelial stem/progenitor cells in utero by Widowski, Helene, Ophelders, Daan R. M. G., van Leeuwen, Anaïs J. C. N., Nikkels, Peter G. J., Severens-Rijvers, Carmen A. H., LaPointe, Vanessa L. S., Cleutjens, Jack P. M., Hütten, Matthias C., Kemp, Matthew W., Payne, Matthew S., Saito, Masatoshi, Usuda, Haruo, Newnham, John P., Jobe, Alan H., Kramer, Boris W., Delhaas, Tammo, Wolfs, Tim G. A. M., Reynaert, Niki L.

“…Background Chorioamnionitis, an intrauterine infection of the placenta and fetal membranes, is a common risk factor for adverse pulmonary outcomes in premature…”
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Mouse strain determines the outcome of wound healing after myocardial infarction by van den Borne, Susanne W.M., van de Schans, Veerle A.M., Strzelecka, Agnieszka E., Vervoort-Peters, Helena T.M., Lijnen, Peter M., Cleutjens, Jack P.M., Smits, Jos F.M., Daemen, Mat J.A.P., Janssen, Ben J.A., Blankesteijn, W. Matthijs

“…Aims Our objective was to study the effect of the genetic background on the wound healing process after myocardial infarction (MI) in mice. Methods and results…”
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Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep by Jellema, Reint K, Lima Passos, Valéria, Zwanenburg, Alex, Ophelders, Daan R M G, De Munter, Stephanie, Vanderlocht, Joris, Germeraad, Wilfred T V, Kuypers, Elke, Collins, Jennifer J P, Cleutjens, Jack P M, Jennekens, Ward, Gavilanes, Antonio W D, Seehase, Matthias, Vles, Hans J, Steinbusch, Harry, Andriessen, Peter, Wolfs, Tim G A M, Kramer, Boris W

“…Hypoxic-ischemic encephalopathy (HIE) is one of the most important causes of brain injury in preterm infants. Preterm HIE is predominantly caused by global…”
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Cardiac hypertrophy is enhanced in PPARα−/− mice in response to chronic pressure overload by Smeets, Pascal J.H., Teunissen, Birgit E.J., Willemsen, Peter H.M., van Nieuwenhoven, Frans A., Brouns, Agnieszka E., Janssen, Ben J.A., Cleutjens, Jack P.M., Staels, Bart, van der Vusse, Ger J., van Bilsen, Marc

“…Aims Peroxisome proliferator-activated receptor-α (PPARα) is a nuclear receptor regulating cardiac metabolism that also has anti-inflammatory properties. Since…”
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Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial by Goossens, Gijs H, Moors, Chantalle C M, van der Zijl, Nynke J, Venteclef, Nicolas, Alili, Rohia, Jocken, Johan W E, Essers, Yvonne, Cleutjens, Jack P, Clément, Karine, Diamant, Michaela, Blaak, Ellen E

“…Blockade of the renin-angiotensin system (RAS) reduces the incidence of type 2 diabetes mellitus. In rodents, it has been demonstrated that RAS blockade…”
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Rapid insulin-mediated increase in microvascular glycocalyx accessibility in skeletal muscle may contribute to insulin-mediated glucose disposal in rats by Eskens, Bart J M, Mooij, Hans L, Cleutjens, Jack P M, Roos, Jozef M A, Cobelens, Johanna E, Vink, Hans, Vanteeffelen, Jurgen W G E

“…It has been demonstrated that insulin-mediated recruitment of microvascular blood volume is associated with insulin sensitivity. We hypothesize that insulin…”
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Early Loss of Peritubular Capillaries after Kidney Transplantation by STEEGH, Floortje M. E. G, GELENS, Marielle A. C. J, NIEMAN, Fred H. M, VAN HOOFF, Johannes P, CLEUTJENS, Jack P. M, JAN VAN SUYLEN, Robert, DAEMEN, Mat J. A. P, VAN HEURN, Ernst L. W, CHRISTIAANS, Maarten H. L, PEUTZ-KOOTSTRA, Carine J

“…Inflammation, interstitial fibrosis (IF), and tubular atrophy (TA) precede chronic transplant dysfunction, which is a major cause of renal allograft loss…”
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Are Periprosthetic Tissue Reactions Observed After Revision of Total Disc Replacement Comparable to the Reactions Observed After Total Hip or Knee Revision Surgery? by PUNT, Ilona M, AUSTEN, Shennah, CLEUTJENS, Jack P. M, KURTZ, Steven M, TEN BROEKE, Rene H. M, VAN RHIJN, Lodewijk W, WILLEMS, Paul C, VAN OOIJ, Andre

“…Comparative study. To compare periprosthetic tissue reactions observed after total disc replacement (TDR), total hip arthroplasty (THA), and total knee…”
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Clinical, radiological, histological and retrieval findings of Activ-L and Mobidisc total disc replacements: a study of two patients by Austen, Shennah, Punt, Ilona M., Cleutjens, Jack P. M., Willems, Paul C., Kurtz, Steven M., MacDonald, Daniel W., van Rhijn, Lodewijk W., van Ooij, André

“…Introduction This study evaluates the short-term clinical outcome, radiological, histological and device retrieval findings of two patients with second…”
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