Search Results - "CLEMENTI, R."
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Structural racism remains a primary public health risk amidst COVID and beyond in the United Kingdom
Published in Journal of public health (Oxford, England) (18-08-2020)Get full text
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A proportion of patients with lymphoma may harbor mutations of the perforin gene
Published in Blood (01-06-2005)“…Perforin mutations have been demonstrated in a proportion of patients diagnosed with the familial form of hemophagocytic lymphohistiocytosis (HLH). In the…”
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Hemophagocytic lymphohistiocytosis due to germline mutations in SH2D1A, the X-linked lymphoproliferative disease gene
Published in Blood (15-02-2001)“…The hemophagocytic lymphohistiocytoses (HLH) comprise a heterogeneous group of disorders characterized by dysregulated activation of T cells and macrophages…”
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Variations of the perforin gene in patients with multiple sclerosis
Published in Genes and immunity (01-07-2008)“…Perforin is involved in cell-mediated cytotoxicity and mutations of its gene ( PRF1 ) cause familial hemophagocytic lymphohistiocytosis (FLH2). PRF1 sequencing…”
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Six novel mutations in the PRF1 gene in children with haemophagocytic lymphohistiocytosis
Published in Journal of medical genetics (01-09-2001)Get full text
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CSL112 (apolipoprotein A-I [human]) reduces the elevation in neutrophil-lymphocyte ratio (NLR) induced by acute myocardial infarction
Published in European heart journal (09-11-2023)“…Abstract Background CSL112 (apolipoprotein A-I [human]) is a novel therapy designed to reduce the risk of recurrent cardiovascular events following acute…”
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IL-6 inhibition with clazakizumab in patients receiving maintenance dialysis: a randomized phase 2b trial
Published in Nature medicine (01-08-2024)“…Inflammation mediated by interleukin-6 (IL-6) is strongly associated with cardiovascular risk. Here we evaluated clazakizumab, a monoclonal antibody targeting…”
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EuPRAXIA@SPARC_LAB Design study towards a compact FEL facility at LNF
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (12-11-2018)“…On the wake of the results obtained so far at the SPARC_LAB test-facility at the Laboratori Nazionali di Frascati (Italy), we are currently investigating the…”
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Design, realization and test of C-band accelerating structures for the SPARC_LAB linac energy upgrade
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (21-11-2016)“…The energy upgrade of the SPARC_LAB photo-injector at LNF-INFN (Frascati, Italy) has been originally conceived replacing one low gradient (13MV/m) 3m long SLAC…”
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SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells
Published in Blood (01-06-2005)“…The adaptor protein SAP regulates signaling through signaling lymphocytic activation molecule (SLAM)–family receptors expressed on T and natural killer (NK)…”
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Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations
Published in Blood (15-09-2002)Get full text
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Expression of p75 chain of IL‐2 receptor in the early immunological reconstitution after allogeneic bone marrow transplantation
Published in Clinical and experimental immunology (01-09-1994)“…SUMMARY Expression of p55 and p75 chains of IL‐2 receptor (IL‐2R) on the surface of both T and natural killer (NK) circulating lymphocytes was investigated in…”
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Beta-endorphin, insulin, ACTH and cortisol plasma levels during oral glucose tolerance test in obesity after weight loss
Published in Hormone and metabolic research (01-02-1990)“…In order to clarify a possible relationship between opioid peptides and glucose homeostasis in obesity we studied Beta-Endorphin (B-Ep), ACTH, cortisol and…”
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Effect of food on the bioavailability of lisinopril, a nonsulfhydryl angiotensin-converting enzyme inhibitor
Published in Journal of pharmaceutical sciences (01-04-1986)“…A randomized, two-way, crossover study was performed on 18 normal volunteers to assess the influence of food on the bioavailability of lisinopril,…”
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Variations of the perforin gene in patients with autoimmunity/lymphoproliferation and defective Fas function
Published in Blood (01-11-2006)“…Mutations decreasing function of the Fas death receptor cause the autoimmune lymphoproliferative syndrome (ALPS) with autoimmune manifestations, spleen/lymph…”
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Atypical features of familial hemophagocytic lymphohistiocytosis
Published in Blood (15-06-2004)“…Familial hemophagocytic lymphohistiocytosis (FHLH) is a rare, rapidly progressive disorder of early childhood characterized by uncontrolled activation of T…”
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Inherited Perforin and Fas Mutations in a Patient with Autoimmune Lymphoproliferative Syndrome and Lymphoma
Published in The New England journal of medicine (30-09-2004)“…A patient who inherited a mutation in the Fas gene from his father and a mutation in the perforin gene from his mother was found to have autoimmune…”
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Effect of repeated doses of L-5-hydroxytryptophan and carbidopa on prolactin and aldosterone secretion in man
Published in Journal of endocrinological investigation (01-02-1989)“…To evaluate changes in serum prolactin and plasma and urine aldosterone after a serotonergic challenge, 8 healthy men (19 to 42 yr), taking dexamethasone (0.75…”
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