Search Results - "CLEMENS, M. R"

Dexmedetomidine versus Midazolam in Procedural Sedation. A Systematic Review of Efficacy and Safety by Barends, Clemens R M, Absalom, Anthony, van Minnen, Baucke, Vissink, Arjan, Visser, Anita

“…To systematically review the literature comparing the efficacy and safety of dexmedetomidine and midazolam when used for procedural sedation. We searched…”
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Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine by Weerink, Maud A. S., Struys, Michel M. R. F., Hannivoort, Laura N., Barends, Clemens R. M., Absalom, Anthony R., Colin, Pieter

“…Dexmedetomidine is an α 2 -adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory…”
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Gemcitabine and oxaliplatin in advanced biliary tract carcinoma: a phase II study by André, T, Reyes-Vidal, J M, Fartoux, L, Ross, P, Leslie, M, Rosmorduc, O, Clemens, M R, Louvet, C, Perez, N, Mehmud, F, Scheithauer, W

“…Advanced biliary tract carcinomas (BTCs) are often diagnosed at an advanced/metastatic stage and have a poor prognosis. The combination of gemcitabine and…”
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Biweekly fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) for patients with metastatic adenocarcinoma of the stomach or esophagogastric junction: a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie by Al-Batran, S.-E., Hartmann, J.T., Hofheinz, R., Homann, N., Rethwisch, V., Probst, S., Stoehlmacher, J., Clemens, M.R., Mahlberg, R., Fritz, M., Seipelt, G., Sievert, M., Pauligk, C., Atmaca, A., Jäger, E.

“…The combination of docetaxel (Taxotere), cisplatin, and fluorouracil improved efficacy in gastric cancer, but was associated with substantial toxicity. This…”
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EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104 by Boeck, S, Jung, A, Laubender, R P, Neumann, J, Egg, R, Goritschan, C, Vehling-Kaiser, U, Winkelmann, C, Fischer von Weikersthal, L, Clemens, M R, Gauler, T C, Märten, A, Klein, S, Kojouharoff, G, Barner, M, Geissler, M, Greten, T F, Mansmann, U, Kirchner, T, Heinemann, V

“…Background: We aimed to identify molecular epidermal growth factor receptor (EGFR) tissue biomarkers in pancreatic cancer (PC) patients treated with the…”
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A randomized double-blind multicenter phase III study of fixed-dose single-administration pegfilgrastim versus daily filgrastim in patients receiving myelosuppressive chemotherapy by Green, M. D., Koelbl, H., Baselga, J., Galid, A., Guillem, V., Gascon, P., Siena, S., Lalisang, R. I., Samonigg, H., Clemens, M. R., Zani, V., Liang, B. C., Renwick, J., Piccart, M. J.

“…Background: We evaluated the efficacy of a single fixed 6 mg dose of pegfilgrastim (a pegylated version of filgrastim) per cycle of chemotherapy, compared with…”
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Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis by Sneyd, J Robert, Absalom, Anthony R, Barends, Clemens R M, Jones, Jordan B

“…Intraoperative and postoperative hypotension occur commonly and are associated with organ injury and poor outcomes. Changes in arterial blood pressure (BP)…”
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Contamination levels of Clostridium estertheticum spores that result in gaseous spoilage of vacuum-packaged chilled beef and lamb meat by Clemens, R.M, Adam, K.H, Brightwell, G

“…To determine the contamination levels of Cl. estertheticum spores that result in gaseous spoilage of vacuum-packaged chilled meats, beef and lamb, stored at…”
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Moderate-to-Deep Sedation Using Target-Controlled Infusions of Propofol and Remifentanil: Adverse Events and Risk Factors: A Retrospective Cohort Study of 2937 Procedures by Barends, Clemens R M, Driesens, Mendy K, van Amsterdam, Kai, Struys, Michel M R F, Absalom, Anthony R

“…In the University Medical Center Groningen in Groningen, the Netherlands, moderate-to-deep sedation is provided by nursing staff trained and supervised by the…”
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Moderate-to-Deep Sedation Using Target-Controlled Infusions of Propofol and Remifentanil: Adverse Events and Risk Factors: A Retrospective Cohort Study of 2937 Procedures by Barends, Clemens R. M., Driesens, Mendy K., van Amsterdam, Kai, Struys, Michel M. R. F., Absalom, Anthony R.

“…BACKGROUND:In the University Medical Center Groningen in Groningen, the Netherlands, moderate-to-deep sedation is provided by nursing staff trained and…”
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Intranasal midazolam for the sedation of geriatric patients with care‐resistant behaviour during essential dental treatment: An observational study by Barends, Clemens R. M., Absalom, Anthony R., Visser, Anita

“…Objectives To describe the efficacy and safety of intranasal midazolam for sedation during essential dental treatment of geriatric patients with major…”
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Pharmacodynamic Interaction of Remifentanil and Dexmedetomidine on Depth of Sedation and Tolerance of Laryngoscopy by Weerink, Maud A S, Barends, Clemens R M, Muskiet, Ernesto R R, Reyntjens, Koen M. E M, Knotnerus, Froukje H, Oostra, Martine, van Bocxlaer, Jan F P, Struys, Michel M. R F, Colin, Pieter J

“…BACKGROUND:Dexmedetomidine is a sedative with modest analgesic efficacy, whereas remifentanil is an opioid analgesic with modest sedative potency. Synergy is…”
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Safety and Considerations of the Anaesthetic Management during Bronchoscopic Lung Volume Reduction Treatments by Roodenburg, Sharyn A, Barends, Clemens R M, Krenz, Grita, Zeedijk, Eelco J, Slebos, Dirk-Jan

“…Different bronchoscopic lung volume reduction approaches are available for a select group of patients with advanced COPD. General anaesthesia is the…”
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Drug selection for ambulatory procedural sedation by Barends, Clemens R M, Absalom, Anthony R, Struys, Michel M R F

“…Ambulatory procedural sedation is used to relieve anxiety, pain and discomfort in a broad spectrum of patients during many types of diagnostic or therapeutic…”
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Effect of dietary phytochemicals on cancer development (review) by Waladkhani, A R, Clemens, M R

“…Vegetables, fruits, and whole grains contain a wide variety of phytochemicals that have the potential to modulate cancer development. There are many…”
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Randomized phase II trial comparing different doses of the bisphosphonate ibandronate in the treatment of hypercalcemia of malignancy by Pecherstorfer, M, Herrmann, Z, Body, J J, Manegold, C, Degardin, M, Clemens, M R, Thürlimann, B, Tubiana-Hulin, M, Steinhauer, E U, van Eijkeren, M, Huss, H J, Thiébaud, D

“…To evaluate the hypocalcemic effect and safety of three different doses of the bisphosphonate ibandronate in tumor-associated hypercalcemia, and to identify…”
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Performance of blow‐by methods in delivering oxygen to pediatric patients during transport: A laboratory study by Barends, Clemens R. M., Yavuz, Pembegul, Molenbuur, Bouwe, Absalom, Anthony R.

“…Summary Background Providing supplemental oxygen with a blow‐by method is used to provide additional oxygen to patients who will not tolerate an oxygen…”
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What’s New in Intravenous Anaesthesia? New Hypnotics, New Models and New Applications by Vellinga, Remco, Valk, Beatrijs I., Absalom, Anthony R., Struys, Michel M. R. F., Barends, Clemens R. M.

“…New anaesthetic drugs and new methods to administer anaesthetic drugs are continually becoming available, and the development of new PK-PD models furthers the…”
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Lipid peroxidation in erythrocytes by Clemens, M R, Waller, H D

“…Erythrocytes might be expected to be highly susceptible to peroxidation. Their membranes are rich in polyunsaturated fatty acids; they are continuously exposed…”
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Serum parathyroid hormone-related protein levels and response to bisphosphonate treatment in hypercalcemia of malignancy by RIZZOLI, R, THIEBAUD, D, DEGARDIN, M, THÜRLIMANN, B, CLEMENS, M. R, EGHBALI, H, BODY, J. J, BUNDRED, N, PECHERSTORFER, M, HERRMANN, Z, HUSS, H. J, RÜCKERT, F, MANEGOLD, C, TUBIANA-HULIN, M, STEINHAUER, E. U

“…The pathogenesis of hypercalcemia of malignancy comprises increased net bone resorption and enhanced renal tubular reabsorption of calcium (Ca). To evaluate…”
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