Search Results - "CLEGG, Jane A."

Antagonists of the Platelet P 2T Receptor:  A Novel Approach to Antithrombotic Therapy by Ingall, Anthony H, Dixon, John, Bailey, Andrew, Coombs, Mandy E, Cox, David, McInally, Judith I, Hunt, Simon F, Kindon, Nicholas D, Teobald, Barry J, Willis, Paul A, Humphries, Robert G, Leff, Paul, Clegg, Jane A, Smith, James A, Tomlinson, Wendy

“…The platelet P 2T receptor plays a major role in platelet aggregation, and its antagonists are predicted to have significant therapeutic potential as…”
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Antagonists of the Platelet P2T Receptor:  A Novel Approach to Antithrombotic Therapy by INGALL, Anthony H., DIXON, John, BAILEY, Andrew, COOMBS, Mandy E., COX, David, MCINALLY, Judith I., HUNT, Simon F., KINDON, Nicholas D., TEOBALD, Barry J., WILLIS, Paul A., HUMPHRIES, Robert G., LEFF, Paul, CLEGG, Jane A., SMITH, James A., TOMLINSON, Wendy

“…The platelet P2T receptor plays a major role in platelet aggregation, and its antagonists are predicted to have significant therapeutic potential as…”
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Comparative biodistribution of methotrexate and monoclonal antibody-methotrexate complexes in mice by Pimm, M V, Caten, J E, Clegg, J A, Jacobs, E, Baldwin, R W

“…The biodistribution of radiolabelled methotrexate and immune complexes of methotrexate and a murine monoclonal anti-methotrexate antibody has been compared in…”
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A phase I/II study of trichosanthin treatment of HIV disease by Byers, V S, Levin, A S, Waites, L A, Starrett, B A, Mayer, R A, Clegg, J A, Price, M R, Robins, R A, Delaney, M, Baldwin, R W

“…Trichosanthin, a ribosomal inhibitor protein, blocks HIV replication in lymphocytes and macrophages. This agent was used to treat 51 patients with advanced HIV…”
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Suppression of antibody responses to ricin A chain (RTA) by monoclonal anti-RTA antibodies by BYERS, V. S, AUSTIN, E. B, CLEGG, J. A, DENTON, G, GUNN, B, HOOI, D, HUDECZ, F, PRICE, M. R, BALDWIN, R. W

“…Balb/c mice treated with an immunotoxin constructed by conjugation of murine monoclonal antibody 791T/36 via a disulfide linker to ricin A chain generate a…”
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Biodistribution and tumour localization of a methotrexate-monoclonal-antibody 791T/36 conjugate in nude mice with human tumour xenografts by Pimm, M V, Clegg, J A, Garnett, M C, Baldwin, R W

“…The blood kinetics and tumour localization of a conjugate of methotrexate (MTX) and MAb 791T/36 were examined in nude mice with human tumour xenografts. The…”
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Biodistribution of a monoclonal antibody-methotrexate conjugate (791T/36-MTX) in patients with colorectal cancer by Ballantyne, K C, Perkins, A C, Pimm, M V, Garnett, M C, Clegg, J A, Armitage, N C, Baldwin, R W, Hardcastle, J D

“…The monoclonal antibody (MAb) 791T/36 which has previously been shown to localise in colorectal cancer has been conjugated to methotrexate (MTX) for potential…”
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