Search Results - "CLAUSS, MATTHIAS"
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Extracellular vesicles: novel communicators in lung diseases
Published in Respiratory research (08-07-2020)“…The lung is the organ with the highest vascular density in the human body. It is therefore perceivable that the endothelium of the lung contributes…”
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Human Endogenous Retrovirus, SARS-CoV-2, and HIV Promote PAH via Inflammation and Growth Stimulation
Published in International journal of molecular sciences (01-04-2023)“…Pulmonary arterial hypertension (PAH) is a pulmonary vascular disease characterized by the progressive elevation of pulmonary arterial pressures. It is…”
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Critical role of endoplasmic reticulum stress in chronic endothelial activation−induced visual deficits in tie2‐tumor necrosis factor mice
Published in Journal of cellular biochemistry (01-11-2018)“…Diabetic retinopathy (DR) is the leading cause of vision loss among working‐age adults. The interplay between hyperglycemia and endothelial activation in…”
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Viral Bad News Sent by EVAIL
Published in Viruses (18-06-2021)“…This article reviews the current knowledge on how viruses may utilize Extracellular Vesicle Assisted Inflammatory Load (EVAIL) to exert pathologic activities…”
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Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2019)“…Proapoptotic and monocyte chemotactic endothelial monocyte-activating protein 2 (EMAPII) is released extracellularly during cigarette smoke (CS) exposure. We…”
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Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia
Published in Scientific reports (24-01-2020)“…One current concept suggests that unchecked proliferation of clonally selected precursors of endothelial cells (ECs) contribute to severe pulmonary arterial…”
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Analysis of MicroRNA Cargo in Circulating Extracellular Vesicles from HIV-Infected Individuals with Pulmonary Hypertension
Published in Cells (Basel, Switzerland) (21-05-2024)“…The risk of developing pulmonary hypertension (PH) in people living with HIV is at least 300-fold higher than in the general population, and illicit drug use…”
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Mice with humanized immune system as novel models to study HIV-associated pulmonary hypertension
Published in Frontiers in immunology (05-08-2022)“…People living with HIV and who receive antiretroviral therapy have a significantly improved lifespan, compared to the early days without therapy…”
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Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction
Published in PloS one (07-03-2014)“…With effective antiretroviral therapy (ART), cardiovascular diseases (CVD) are emerging as a major cause of morbidity and death in the aging HIV-infected…”
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An angiogenic role for the human peptide antibiotic LL-37/hCAP-18
Published in The Journal of clinical investigation (01-06-2003)“…Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human cathelicidin…”
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Pentoxifylline, inflammation, and endothelial function in HIV-infected persons: a randomized, placebo-controlled trial
Published in PloS one (09-04-2013)“…Untreated HIV may increase the risk of cardiovascular events. Our preliminary in vitro and in vivo research suggests that pentoxifylline (PTX) reduces vascular…”
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A pilot trial of pentoxifylline on endothelial function and inflammation in HIV-infected patients initiating antiretroviral therapy
Published in AIDS (London) (24-08-2016)Get full text
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An angiogenic role for the human peptide antibiotic LL-37/hCAP-18
Published in The Journal of clinical investigation (01-06-2003)“…Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human cathelicidin…”
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Impact of human immunodeficiency virus on pulmonary vascular disease
Published in Global Cardiology Science & Practice (30-06-2021)“…With the advent of anti-retroviral therapy, non-AIDS-related comorbidities have increased in people living with HIV. Among these comorbidities, pulmonary…”
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IFATS Collection: Adipose Stromal Cell Differentiation Is Reduced by Endothelial Cell Contact and Paracrine Communication: Role of Canonical Wnt Signaling
Published in Stem cells (Dayton, Ohio) (01-10-2008)“…Adipose stromal cells (ASC) are multipotential mesenchymal progenitor cells that are readily induced to undergo adipogenic differentiation, and we have…”
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Blood monocyte concentration is critical for enhancement of collateral artery growth
Published in American journal of physiology. Heart and circulatory physiology (01-12-2002)“…Arteriogenesis has been associated with the presence of monocytes/macrophages within the collateral vessel wall. We tested the hypothesis that arteriogenesis…”
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TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)
Published in Atherosclerosis plus (01-12-2022)“…TACE/ADAM17 is a membrane bound metalloprotease, which cleaves substrates involved in immune and inflammatory responses and plays a role in coronary artery…”
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Molecular biology of the VEGF and the VEGF receptor family
Published in Seminars in thrombosis and hemostasis (2000)“…Vascular endothelial growth factor (VEGF) is the founding member of a still growing family of endothelial cell growth factors. The diverse functions of VEGF…”
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Pro-inflammatory angiogenesis is mediated by p38 MAP kinase
Published in Journal of cellular physiology (01-03-2011)“…Chronic inflammation is tightly linked to diseases associated with endothelial dysfunction including aberrant angiogenesis. To better understand the…”
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