Search Results - "CLARKSON, Thomas W"
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The Toxicology of Mercury and Its Chemical Compounds
Published in Critical reviews in toxicology (01-09-2006)“…This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern. Human…”
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The Toxicology of Mercury — Current Exposures and Clinical Manifestations
Published in The New England journal of medicine (30-10-2003)“…Mercury poisoning still occurs as a result of accidental and occupational exposure. For the general population, however, the main concern is the possible…”
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Mechanisms of mercury disposition in the body
Published in American journal of industrial medicine (01-10-2007)“…Today the most widespread human exposures to mercury are to mercury vapor emitted from amalgam tooth fillings, to ethylmercury as a preservative in vaccines,…”
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4
Fish consumption and prenatal methylmercury exposure: Cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development study
Published in Neurotoxicology (Park Forest South) (01-12-2011)“…People worldwide depend upon daily fish consumption as a major source of protein and other nutrients. Fish are high in nutrients essential for normal brain…”
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The Chemical Nature of Mercury in Human Brain Following Poisoning or Environmental Exposure
Published in ACS chemical neuroscience (15-12-2010)“…Methylmercury is among the most potentially toxic species to which human populations are exposed, both at high levels through poisonings and at lower levels…”
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Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study
Published in The Lancet (British edition) (17-05-2003)“…Exposure to methylmercury (MeHg) before birth can adversely affect children's neurodevelopment. The most common form of prenatal exposure is aternal fish…”
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Associations of maternal long-chain polyunsaturated fatty acids, methyl mercury, and infant development in the Seychelles Child Development Nutrition Study
Published in Neurotoxicology (Park Forest South) (01-09-2008)“…Fish consumption during gestation can provide the fetus with long-chain polyunsaturated fatty acids (LCPUFA) and other nutrients essential for growth and…”
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Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy
Published in Neurotoxicology (Park Forest South) (01-09-2008)“…Fish contain nutrients that promote optimal brain growth and development but also contain methylmercury (MeHg) that can have toxic effects. The present study…”
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Postnatal exposure to methyl mercury from fish consumption: A review and new data from the Seychelles Child Development Study
Published in Neurotoxicology (Park Forest South) (01-05-2009)“…Fish is an important source of nutrition worldwide. Fish contain both the neurotoxin methyl mercury (MeHg) and nutrients important for brain development. The…”
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Transport of a neurotoxicant by molecular mimicry: the methylmercury-L-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2
Published in Biochemical journal (01-10-2002)“…Methylmercury (MeHg) readily crosses cell membrane barriers to reach its target tissue, the brain. Although it is generally assumed that this rapid transport…”
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Prenatal exposure to dental amalgam Evidence from the Seychelles Child Development Study main cohort
Published in The Journal of the American Dental Association (1939) (01-11-2011)“…Dental amalgams contain approximately 50 percent metallic mercury and emit mercury vapor during the life of the restoration. Controversy surrounds whether…”
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Nutritional factors may modify the toxic action of methyl mercury in fish-eating populations
Published in The Journal of nutrition (01-05-2003)“…The historical record of clinical cases of methyl mercury poisoning dates back to the 19th century when the first chemical synthesis occurred. The potent…”
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Accelerated urinary excretion of methylmercury following administration of its antidote N-acetylcysteine requires Mrp2/Abcc2, the apical multidrug resistance-associated protein
Published in The Journal of pharmacology and experimental therapeutics (01-07-2007)“…N-Acetylcysteine (NAC) is a sulfhydryl-containing compound that produces a dramatic acceleration of urinary methylmercury (MeHg) excretion in poisoned mice,…”
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Validity of methyl mercury hair analysis: mercury monitoring in human scalp/nude mouse model
Published in Journal of applied toxicology (01-05-2008)“…Objective. The grafting of human scalp hair was used as a new application of this method to explore methyl mercury incorporation into human hair and to…”
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Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development study
Published in Neurotoxicology (Park Forest South) (01-05-2008)“…The Seychelles Child Development Study was designed to test the hypothesis that prenatal exposure to MeHg from maternal consumption of a diet high in fish is…”
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The Three Modern Faces of Mercury
Published in Environmental health perspectives (01-02-2002)“…The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam…”
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Overview of the clinical toxicity of mercury
Published in Annals of clinical biochemistry (01-07-2006)“…Mercury is ubiquitous in the environment and therefore every human being, irrespective of age and location, is exposed to one form of mercury or another. The…”
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Seychelles Child Development Study: many more avenues for scientific collaboration
Published in Neurotoxicology (Park Forest South) (01-12-2020)Get full text
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Benchmark concentrations for methyl mercury obtained from the 9-year follow-up of the Seychelles Child Development Study
Published in Neurotoxicology (Park Forest South) (01-09-2006)“…Methyl mercury (MeHg) is highly toxic to the developing nervous system. Human exposure is mainly from fish consumption since small amounts are present in all…”
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Methylmercury and neurodevelopment: Longitudinal analysis of the Seychelles child development cohort
Published in Neurotoxicology and teratology (01-09-2006)“…Background: The Seychelles Child Development Study (SCDS) has been longitudinally following a cohort of over 700 children enrolled in 1989. Their mothers…”
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